DataSheet1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.docx by Jose M. Ferrero (6705797)

“…In order to investigate these mechanisms, we developed a novel computational model of acute myocardial ischemia which couples a) an electrophysiologically detailed human cardiomyocyte model that incorporates modifications to account for ischemia-induced changes in transmembrane currents, with b) a model of cardiac tissue and extracellular K⁺ transport. …”

Loss of <i>bmm</i> function in the somatic cells of the gonad with an independent GAL4 line affects whole-body triglyceride breakdown in males but not females. by Lianna W. Wat (8339454)

“…(C) Between 0 and 12 hours STV, the magnitude of triglyceride breakdown in <i>tj>UAS-bmm-RNAi</i> was similar to <i>tj>+</i> and <i>+>UAS-bmm-RNAi</i> control males; however, between 12 and 24 hours STV, there was no significant decrease in triglyceride levels in <i>tj>UAS-bmm-RNAi</i> males, in contrast to <i>tj>+</i> and <i>+>UAS-bmm-RNAi</i> control males, in which we observed a significant decrease in triglyceride storage STV (<i>p</i> = 9.7 × 10⁻⁴, 0.0018, and 0.099 for 0–12 hours and 0.37, 1.9 × 10⁻⁵, and 0.028 for 12–24 hours, respectively; one-way ANOVA followed by Tukey HSD test). …”

Image_1_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Image_2_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Image_3_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Response kinetics and relationship to Weber’s law in the m7 controller (Fig 5). by Jonas V. Grini (15374504)

“…<p>The set-point of <i>A</i> is 3.0. (a) Step-wise increase of <i>k</i>₁ from 1.0 to 5.0 at time <i>t</i>=100 at different and constant background perturbations <i>k</i>₃ (0–128.0, applied in phases 1 and 2). …”

53 proteins change in abundance with age. by Stephanie M. Zimmerman (449532)

<i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality... by Ashwani Kumar (55732)

“…The mechanistic interpretation of developed models explains the role of different structural attributes in predicting the pIC₅₀ of pyrazole sulfonamides extracted from the crystal structure of Leishmania major N-myristoyltransferase (NMT) along with co-crystallized myristoyl-CoA and ligands NMT106, NMT157, NMT187 and NMT236 (PDB ID: 4A2Z, 4A30, 4A32, 2WSA). …”

The Protein <i>O</i>-glucosyltransferase Rumi Modifies Eyes Shut to Promote Rhabdomere Separation in <i>Drosophila</i> by Amanda R. Haltom (664189)

“…The intracellular accumulation of Eys and the IRS defect worsen in <i>rumi</i> mutants raised at a higher temperature, and are accompanied by a ∼50% decrease in the total level of Eys. …”

Presentation_1_Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans.pdf by Emilia Boiadjieva Knöpfel (6795341)

“…We show that neutral amino acid antiporter LAT2 (Slc7a8) and uniporter TAT1 (Slc16a10) are expressed on mouse ciliary epithelium and LAT2 also in lens epithelium. …”

Image_2_The impact of genetic modified Ma bamboo on soil microbiome.pdf by Kai Wang (21246)

“…<p>Evaluating the potential alteration of microbial communities is a vital step for biosafety of genetic modified plants. …”

Data_Sheet_2_The impact of genetic modified Ma bamboo on soil microbiome.fasta by Kai Wang (21246)

“…<p>Evaluating the potential alteration of microbial communities is a vital step for biosafety of genetic modified plants. …”

Image_1_The impact of genetic modified Ma bamboo on soil microbiome.pdf by Kai Wang (21246)

“…<p>Evaluating the potential alteration of microbial communities is a vital step for biosafety of genetic modified plants. …”

Data_Sheet_1_The impact of genetic modified Ma bamboo on soil microbiome.fasta by Kai Wang (21246)

“…<p>Evaluating the potential alteration of microbial communities is a vital step for biosafety of genetic modified plants. …”

Data Sheet 1_Milciclib-mediated CDK2 inhibition to boost radiotherapy sensitivity in colorectal cancer.pdf by Junjie Ma (730463)

“…When combined with irradiation, Milciclib led to a 20% increase in the proportion of cells in the G1 phase and a 10% decrease in the G2 phase, suggesting an alteration in cell cycle distribution. …”

DataSheet_1_Systematic review and meta-analysis of the current literature on tocilizumab in patients with refractory Takayasu arteritis.docx by Limei Kang (14584889)

“…Approximately 76% (95% CI 58-87%) of patients achieved a decrease in glucocorticoid dosage. Meanwhile, patients with TAK had a remission rate of 79% (95% CI 69-86%), a relapse rate of 17% (95% CI 5-45%), an imaging progress rate of 16% (95% CI 9-27%), and a retention rate of 68% (95% CI 50-82%). …”

Table_1_The Impact of COVID-19 Confinement on Tinnitus and Hearing Loss in Older Adults: Data From the LOST in Lombardia Study.DOCX by Carlotta Micaela Jarach (12203687)

“…In 2020 compared to 2019, among individuals with tinnitus, those with increasing severity (5.0%) were similar to those decreasing it (5.3%). …”

Crz signaling influences osmotic and ionic stresses. by Meet Zandawala (491178)

Evidence for Substrate Preorganization in the Peptidylglycine α-Amidating Monooxygenase Reaction Describing the Contribution of Ground State Structure to Hydrogen Tunneling by Neil R. McIntyre (2249155)

“…The primary deuterium KIE displays a linear decrease with respect to acyl chain length for straight-chain <i>N</i>-acylglycine substrates. …”

Evidence for Substrate Preorganization in the Peptidylglycine α-Amidating Monooxygenase Reaction Describing the Contribution of Ground State Structure to Hydrogen Tunneling by Neil R. McIntyre (2249155)

“…The primary deuterium KIE displays a linear decrease with respect to acyl chain length for straight-chain <i>N</i>-acylglycine substrates. …”