Data_Sheet_1_Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7.docx by Ana Dios-Esponera (6422411)

“…Lymphocyte homing to lymph nodes requires that they cross endothelial barriers present in blood vessels and lymphatics. This multi-step process requires a remodeling of the lymphocyte plasma membrane, which is mediated by the dynamic re-arrangement of the actin cytoskeleton. …”

Effect of FAAH inhibition on depressive-like behavior in WKY rats. by K. Yaragudri Vinod (323103)

“…<p>Treatment with URB597 (0.3 mg/kg, i.p. for 7 days) elicited a significant decrease in total time spent in immobility (50%, p<0.01; A) and a marked increase in sucrose intake (48%, p<0.05; B) without any effect on the spontaneous locomotor activity in the open field (C) in WKY rats compared to vehicle treated WKY rats.…”

c-MET Protects Breast Cancer Cells from Apoptosis Induced by Sodium Butyrate by Bo Sun (177052)

Lack of off-target silencing of other keratins by lead inhibitor for K12 Leu132Pro mutation, siRNA K12-L132P-9. by Haihui Liao (192426)

Soy isoflavones genistein and daidzein protect primary cortical cultures from Tat neurotoxicity. by Sheila M. Adams (322032)

“…<p>Primary cortical neurons were exposed to estrogen (0.1, 2.0 and 10 nM), or isoflavones (0.05, 0.2 and 1 µM) 24 hr prior to the start of Tat_1–86 B (50 nM) treatment. Cell viability was assessed by Live/Dead assay. …”

Table_1_The Metabolic Changes and Immune Profiles in Patients With COVID-19.pdf by Bing He (135034)

“…<p>To explore the metabolic changes and immune profiles in patients with COVID-19, we analyzed the data of patients with mild and severe COVID-19 as well as young children with COVID-19. …”

Synthesis and properties of fluorinated copolymerized polyimide films by Chuanhao Cao (10396166)

“…With the increase of 6FDA in the proportion of dianhydride, the tensile strength of the polyimide film showed a decreasing trend. This work provided a high performance film. …”

Lkb1-deficiency alters the expression of Notch signalling components and leads to the abnormal intestinal secretory cell differentiation. by Boris Y. Shorning (232815)

“…D, Delta ligand (Dll1) immunostaining at day 6 in induced <i>Cre</i>-negative Lkb1 <i>fl/fl</i> (+/+) and Lkb1-deficient (‘−/−’) intestines displaying a decrease in Dll1 expression in Paneth and goblet cells of Lkb1-deficient intestines. …”

Changes in expression of epithelial and mesenchymal proteins in primary human small airway epithelial cells (SAEC) and large airway epithelial cells (LAEC) stimulated with TGFβ1 <i... by Balarka Banerjee (107946)

“…(A) Initial immunoblots suggested a marked increase in mesenchymal markers and corresponding decrease in epithelial markers after 96 h of stimulation. …”

Phenotypic analyses of tumour cells in co-culture experiments. by Victor Trevino (8900)

“…The presence of normal cells are seen to (A) increase the population doubling time (PDT), (B) decrease the total cell number, (C) have no significant effect on apoptosis, (D) decrease the number and (E) size of the cell clusters and (F) increase the number of single cells. …”

RPL37, RPS15, and RPS20 bind to and regulate MdmX levels. by Lilyn Daftuar (433919)

“…Endogenous proteins were detected by immunoblotting with the indicated antibodies. (g) Decrease in MdmX mRNA by RPL37. U2OS cells were seeded in 60 mM tissue culture plates and transfected with Myc-RP (0–5.0 µg). …”

Conditions required for, supporting, and suppressing, interferon induction in the absence of NS1. by Alison C. Vicary (15307178)

“…In brief, we find that both replication and export are required for maximal interferon induction in the absence of the NS1 antagonist, and that, additionally, the presence of replicating defective viral genomes greatly enhances the interferon response. The boxed step is absolutely required for the increase in interferon in the absence of NS1, whereas nonboxed steps modulate the process. …”

<em>Trypanosoma vivax</em> Infections: Pushing Ahead with Mouse Models for the Study of <em>Nagana</em>. II. Immunobiological Dysfunctions by Marie Christine Blom-Potar (244113)

“…More precisely, after an initial increase that primarily involves CD4⁺ T cells and macrophages, the number of splenic B cells decreases in a step-wise manner. Our results show that while infection triggers the activation and proliferation of Hematopoietic Stem Cells, Granulocyte-Monocyte, Common Myeloid and Megacaryocyte Erythrocyte progenitors decrease in number in the course of the infection. …”

Evidence for selection on SARS-CoV-2 RNA translation revealed by the evolutionary dynamics of mutations in UTRs and CDSs by Lin Zhu (192179)

“…<p>RNA translation is the rate-limiting step when cells synthesize proteins. Elevating translation efficiency (TE) is intuitively beneficial. …”

Functional characterization of differentiated astrocytes. by In Ki Cho (6494564)

“…<p>(A) Representative traces of ionic currents evoked by ramp protocol (left) and voltage-step protocol (right) in cultured WT, HD, and shHD astrocytes. …”

Effect of depletion or inactivation of PAR-2 on Erk1/2 phosphorylation and cell proliferation. by Song Han (470055)

Quality measures of the reconstructed hierarchies for the “hard” synthetic data set. by Gergely Tibély (504070)

Immunoblot expressions of TTR levels in HepG2 cells exposed to low (1.0 µg/mL) and high (10 ug/mL) concentrations of warfarin for 24 hrs. by Ramasamy Saminathan (358756)

Permeability Changes in LLC-PK₁ Cell Layers Induced by Nutraceutical Compounds. by Joanna Mercado (484241)

Chronic intermittent ethanol (CIE) exposure alters the time course of STDP. by Sven Kroener (321008)

“…This was due both to a decrease in potentiation at the late time-point and to the continued increase in LTP in both CIE-exposed groups of mice. …”