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web decrease » mean decrease (Expand Search), teer decrease (Expand Search), step decrease (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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4341
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4342
Change of the immune microenvironment in MC38 S.C. tumors of <i>S100a4-Cre; Ext1</i><sup><i>f/f</i></sup> mice.
Published 2023“…Data represent mean ± SEM (N = 6 for each cohort, unpaired t-test). Scale bar = 50 μm. (C) Microarray analysis of MC38 S.C. tumor of <i>S100a4-Cre; Ext1</i><sup><i>f/f</i></sup> and control mice (N = 4 for each cohort). …”
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4343
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4344
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4345
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4346
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4347
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4348
Flow chart for patients inclusion.
Published 2025“…Following this, antibiotic prescription was associated with a decreased 28-day mortality rate (2.3% vs. 3.6%) and in-hospital mortality rate (4.0% vs. 5.0%) compared with the control group. …”
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4349
The outcome measures in IPTW analysis.
Published 2025“…Following this, antibiotic prescription was associated with a decreased 28-day mortality rate (2.3% vs. 3.6%) and in-hospital mortality rate (4.0% vs. 5.0%) compared with the control group. …”
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4350
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4351
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4352
Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis
Published 2024“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”
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4353
Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis
Published 2024“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”
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4354
Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis
Published 2024“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”
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4355
Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis
Published 2024“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”
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4356
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4357
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4358
Mucin deglycosylase activity of ChiA2.
Published 2014“…A 50-fold decrease in the % area density of the spot was observed for ChiA2-treated rabbit mucin compared to the untreated one. …”
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4359
GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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4360