Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Growth curve of a representative patient. by Dalit Modan-Moses (307368)

Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies by Brianna D. Mackie (9212677)

“…Its cell-permeable analogue <b>DC432</b> (IC₅₀ of 54 ± 4 nM) decreases the N-terminal methylation level of the regulator of chromosome condensation 1 and SET proteins in HCT116 cells. …”

Variable importance plot. by Mariana S. Silva-Alves (3615719)

Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes by Wipawee Wongchana (5367968)

“…A similar impact on IL-10 production was observed when Notch signaling was inhibited with a gamma-secretase inhibitor (GSI). …”

Evaluation of Efficiency of Liposome-Entrapped Iridium(III) Complexes Inhibiting Tumor Growth In Vitro and In Vivo by Huiyan Hu (9376570)

“…In addition, we also found that 3alip, 3blip, and 3clip triggered ferroptosis and autophagy. …”

Begg’s funnel plot for publication bias test. by Yupeng Luo (527348)

Rotational Periodicity Display of the Tunable Wettability Pattern in a Photoswitch Based on a Response Bilayer Photonic Crystal by Yong Qi (429532)

A structure of single hidden layers. by Zulqurnain Sabir (12269556)

Hemodynamic changes and baroreflex equilibrium diagram during administration of SNP. by Aimi Yokoi (16819464)

Hemodynamic changes and baroreflex equilibrium diagram during administration of vericiguat. by Aimi Yokoi (16819464)

Summary of the effect of maternal immune activation on serotonin and dopamine. by Pei-Tan Hsueh (752475)

“…Moreover, the total number and distribution of tph2-expressing 5-HTergic neurons, and the diameter of the 5-HTergic axon hillocks were decreased at the age of 8 weeks. We concluded that maternal immune activation induced by exposure to a low dose of LPS decreased cerebral 5-HT in parallel with the down-regulation of 5-HT-related genes (tph2 and slc6a4), resulting in anxiety-like behavior in the female offspring.…”

Dinucleotide A/T and G/C patterns. by Sheila M. Reynolds (245934)

“…<p>These figures show the frequency of dinucleotides composed exclusively of A/T (red) and G/C (blue). The <i>H. sapiens</i> patterns show no evidence of bp periodicity, while the <i>S. cerevisiae</i> patterns do, with peaks in the A/T pattern at 13, 24, 36, 47, 58, and 68, and peaks in the C/G pattern at 0, 20, 32, 42, 50, 61, and 72 bp from the dyad. …”

Normalized avalanche size with respect to changes in (<i>t</i>/<i>f</i>) value. by Heesuk Kang (18086720)

“…However, the number of countries (yellow) that experience sudden failure increases from (D) to (E). A red node indicates the country in which the failure originated, orange nodes indicate countries to which the failure was transmitted at an intermediate stage, and yellow nodes indicate countries to which the failure was transmitted at the critical point.…”

Apo A-1 expression analysis. by Chiara Fania (4117279)

Lsd1 is abundantly expressed in osteoblasts and important for osteoblast differentiation. by Petri Rummukainen (4247122)

Data_Sheet_1_Bather Shedding as a Source of Human Fecal Markers to a Recreational Beach.pdf by Dong Li (212687)

“…Offshore sources appeared unlikely, since FIB and fecal markers decreased along a spatial gradient from the surf zone toward nearshore and offshore ocean waters. …”

Bayesian framework for global RT alignment and matching spectra to peptides. by Albert Tian Chen (6900215)

ßNGF expression. by Cédric Mauprivez (819048)

“…When mast cells are activated, their granule content is released outside the cell, thus the immunostaining for the marker progressively decreases within the cell. Magnification bars, <b>A</b> to <b>E</b>: 50 μm; <b>F</b> to <b>I</b>: 10 μm. …”

Proper Notch signaling is required for the differentiation of <i>agr2</i>^<i>+</i> epidermal mucous cells and <i>pvalb8</i>-positive cells. by Yu-Fen Lu (171691)

“…<b>(C).</b> Substantial decreases in <i>agr2</i>^<i>+</i> EMC numbers in the trunks and yolks were detected in embryos treated with 50 μM of MK0752 from 10–14 hpf or 11–15 hpf but not from 10–13 hpf or 11–14 hpf, as compared to respective DMSO-treated embryos during 10–14 hpf or 11–15 hpf. …”