Image_4_Comprehensive Flow Cytometric Characterization of Bronchoalveolar Lavage Cells Indicates Comparable Phenotypes Between Asthmatic and Healthy Horses But Functional Lymphocyt... by A. Elisabeth Gressler (11174997)

“…Cytokine production differences of BAL lymphocytes from horses with sEA compared to healthy horses’ cells point towards a functional difference, namely increased local type 3 responses in sEA.…”

Table_2_Elevated triglyceride-glucose index associated with increased risk of diabetes in non-obese young adults: a longitudinal retrospective cohort study from multiple Asian coun... by Jian Han (211805)

“…A non-linear relationship was observed with an inflection point at 7.3. …”

Table_3_Elevated triglyceride-glucose index associated with increased risk of diabetes in non-obese young adults: a longitudinal retrospective cohort study from multiple Asian coun... by Jian Han (211805)

“…A non-linear relationship was observed with an inflection point at 7.3. …”

Table_1_Elevated triglyceride-glucose index associated with increased risk of diabetes in non-obese young adults: a longitudinal retrospective cohort study from multiple Asian coun... by Jian Han (211805)

“…A non-linear relationship was observed with an inflection point at 7.3. …”

Table_4_Elevated triglyceride-glucose index associated with increased risk of diabetes in non-obese young adults: a longitudinal retrospective cohort study from multiple Asian coun... by Jian Han (211805)

“…A non-linear relationship was observed with an inflection point at 7.3. …”

Change in foldability during evolution for subsets of chain size: Distribution of domain length for domains appearing a) 3.8-1.5 Gya and b) 1.5-0 Gya. by Cédric Debès (102067)

“…<p>Abundancies were colored according to the average SMCO, the difference between the end points of the polynomial regression of SMCO in this dataset, for the specified initial (a) and later (b) time period. …”

Image_3_Pro Nerve Growth Factor and Its Receptor p75NTR Activate Inflammatory Responses in Synovial Fibroblasts: A Novel Targetable Mechanism in Arthritis.jpeg by Luciapia Farina (12194915)

“…The blocking of NGF binding to p75NTR using specific inhibitors led instead to the disruption of this pro-inflammatory loop, reducing activation of the p38 and JNK intracellular pathways and decreasing inflammatory cytokine production. Overall, our data demonstrate that an active proNGF/p75NTR axis promotes pro-inflammatory responses in synovial fibroblasts, thereby contributing to chronic synovial inflammation, and point to the possible use of p75NTR inhibitors as a novel therapeutic approach in chronic arthritis.…”

Image_4_Pro Nerve Growth Factor and Its Receptor p75NTR Activate Inflammatory Responses in Synovial Fibroblasts: A Novel Targetable Mechanism in Arthritis.jpeg by Luciapia Farina (12194915)

“…The blocking of NGF binding to p75NTR using specific inhibitors led instead to the disruption of this pro-inflammatory loop, reducing activation of the p38 and JNK intracellular pathways and decreasing inflammatory cytokine production. Overall, our data demonstrate that an active proNGF/p75NTR axis promotes pro-inflammatory responses in synovial fibroblasts, thereby contributing to chronic synovial inflammation, and point to the possible use of p75NTR inhibitors as a novel therapeutic approach in chronic arthritis.…”

Image_2_Pro Nerve Growth Factor and Its Receptor p75NTR Activate Inflammatory Responses in Synovial Fibroblasts: A Novel Targetable Mechanism in Arthritis.jpeg by Luciapia Farina (12194915)

“…The blocking of NGF binding to p75NTR using specific inhibitors led instead to the disruption of this pro-inflammatory loop, reducing activation of the p38 and JNK intracellular pathways and decreasing inflammatory cytokine production. Overall, our data demonstrate that an active proNGF/p75NTR axis promotes pro-inflammatory responses in synovial fibroblasts, thereby contributing to chronic synovial inflammation, and point to the possible use of p75NTR inhibitors as a novel therapeutic approach in chronic arthritis.…”

Image_1_Pro Nerve Growth Factor and Its Receptor p75NTR Activate Inflammatory Responses in Synovial Fibroblasts: A Novel Targetable Mechanism in Arthritis.jpeg by Luciapia Farina (12194915)

“…The blocking of NGF binding to p75NTR using specific inhibitors led instead to the disruption of this pro-inflammatory loop, reducing activation of the p38 and JNK intracellular pathways and decreasing inflammatory cytokine production. Overall, our data demonstrate that an active proNGF/p75NTR axis promotes pro-inflammatory responses in synovial fibroblasts, thereby contributing to chronic synovial inflammation, and point to the possible use of p75NTR inhibitors as a novel therapeutic approach in chronic arthritis.…”

Phenotype of Ad5-specific CD8⁺ T-cells. by Natalie A. Hutnick (234410)

“…Black bars represent a significant difference between the serogroups at that time point. …”

DataSheet_1_Revitalizing quality of life: a case report on the beneficial impact of comprehensive rehabilitation therapy in treating upper-limb lymphedema following breast cancer s... by Yan-Fang Sui (16381908)

“…The patient’s quality of life was also significantly improved, as evidenced by the increase in the Activities of Daily Living score from 95 to 100 points, the increase in the the Functional Assessment of Cancer Therapy: Breast score from 53 to 79 points, and the decrease in the Kessler Psychological Distress Scale score from 24 to 17 points.…”

Supplementary materials: Real-world clinical outcomes and rationale for initiating abatacept as a first-line biologic for patients with anticitrullinated protein antibody- and rheu... by Alexandrina Balanean (20282985)

“…<b>Conclusion:</b> In this analysis of patients with ACPA+ and RF+ RA treated with abatacept as a firstline bDMARD in a clinical practice setting, clinical outcomes and remission rates were improved at all time points, providing real-world evidence to further support the use of abatacept in this patient population.…”

Supplementary file 1_Association between the hemoglobin-to-red cell distribution width ratio and three-month unfavorable outcome in older acute ischemic stroke patients: a prospect... by Huang Luwen (20861381)

“…Each 1-unit increase in HRR on the left side of the infection point was associated with a 24.0% decrease in the likelihood of adverse outcomes (OR = 0.76, 95% CI: 0.66–0.86, p < 0.001). …”

Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (<i>N</i> = 19) by Carlijn de Roos (8061239)

“…These symptoms can cause severe impairment to a child’s functioning and, if left untreated, have negative long-term consequences. …”

DataSheet1_The integrated analysis of gut microbiota and metabolome revealed steroid hormone biosynthesis is a critical pathway in liver regeneration after 2/3 partial hepatectomy.... by Runbin Sun (141863)

“…Targeting specific gut bacterial strains, especially increasing the abundance of Akkermansia and decreasing the abundance of Enterobacteriaceae, may be a promising beneficial strategy to modulate systemic metabolism such as amino acid and nucleotide metabolism and promote liver regeneration.…”

Data_Sheet_1_The impact of Helicobacter pylori eradication with vonoprazan-amoxicillin dual therapy combined with probiotics on oral microbiota: a randomized double-blind placebo-c... by Ruolin Peng (17078266)

“…Beta diversity and LEfSe analysis revealed distinct structures, and KEGG analysis showed distinct signaling pathways of tongue coating flora at three time points. There was a significant reduction of Firmicutes and Lactobacillus after H. pylori erdication. …”

Supplementary file 1_Global burden of childhood otitis media attributable to secondhand smoke from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.pd... by Bei Li (90587)

“…</p>Conclusion<p>While there has been a general decrease in the global burden of childhood otitis media linked to secondhand smoke exposure. …”

Analysis of Splenic Hematopoietic Cells in MCMV Infected Mice by Chris A Benedict (27786)

“…The higher percentage of cells expressing GFP as fraction of the total splenocytes observed at 72 h after infection (9.9%) compared with 48h (1.6%) is considered in the context of the increased lymphocyte death at this time point (shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.0020016#ppat-0020016-g004" target="_blank">Figure 4</a>B). …”

Charge Distribution in Cationic Molybdenum Imido Alkylidene <i>N</i>‑Heterocyclic Carbene Complexes: A Combined X‑ray, XAS, XES, DFT, Mössbauer, and Catalysis Approach by Mathis Benedikter (9726148)

“…Single-crystal X-ray data were used as a starting point for the optimization of the geometries of the catalysts at the PBE0-D3BJ/def2-SVP level of theory; the obtained data were compared to those obtained from X-ray absorption (XAS) and emission spectroscopy (XES). …”