Image_2_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

“…</p>Discussion<p>These findings demonstrate that 50% reduction in SIRT1 is sufficient to induce the hallmarks of skeletal aging namely, decreased cortical thickness and increased porosity in female mice, highlighting the role of SIRT1 as a regulator of cortical bone quantity and quality. …”

Image_1_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

“…</p>Discussion<p>These findings demonstrate that 50% reduction in SIRT1 is sufficient to induce the hallmarks of skeletal aging namely, decreased cortical thickness and increased porosity in female mice, highlighting the role of SIRT1 as a regulator of cortical bone quantity and quality. …”

Three variants lower the rheobase and increase firing frequency of Ca_V3.3, while the A398V variant shows the opposite effect. by Yousra El Ghaleb (22075892)

Cerebral edema and clinical signs of CM are decreased in α_D ^-/- mice infected with <i>P</i>. <i>berghei</i> ANKA. by Isaclaudia G. de Azevedo-Quintanilha (8173734)

Analysis of MD simulations for the SP domain of native PC and its mutant structures (L305R, W342C, G403R, V420E, and W444C) over 200 ns simulations. by Mahvash Farajzadeh-Dehkordi (17468232)

SMC-specific knockout of Klf5 (smcKlf5^−/−) exacerbates the progression of Ang II–induced AAA by facilitating ROS formation. by Dong Ma (584680)

PSG-specific <i>Fzr</i> mutation decreases the expression of silk protein genes. by Wenliang Qian (639395)

“…For the significance test: *<i>P</i> < 0.05, **<i>P</i> < 0.01, and ***<i>P</i> < 0.001 versus the control. Scale bar, 1cm. WT, wild type. L5D3, the third day of the fifth larval instar; L5D5, the fifth day of the fifth larval instar; W0, just wandering.…”

Decreased expression of Rho in the <i>nrl</i>-KO retinas as detected by dot blotting. by Fei Liu (21082)

WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression. by Ayana E. Morales (17756335)

“…<b>C.</b> RT-qPCR of WT1, p<0.05(*), vFLIP(ns), LANA, p<0.0001(****), K8.1, p<0.0001(****), and BCL2 p<0.05(*) in the setting of WT1 knockdown in ISLK BAC-16 with WT1 siRNA in comparison to a control siRNA using two-sided, unpaired student’s t-tests. …”

Prey establishment and decrease in inter-population contacts protects T6SS sensitive lineages. by Marta Rudzite (15991136)

“…Images of whole microcolonies taken after 48h incubation at 37°C on LB with (2% w/v) agar, a representative image of 3 biological repeats is shown.…”

Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production. by Bei Wang (116772)

MRI imaging and analysis, revealing decreased volume and thickness of placentas exposed to intrauterine inflammation. by Solange N. Eloundou (6551627)

Activating cAMP synthesis decreases liberation of propionyl-CoA from cholesterol. by Kaley M. Wilburn (12060476)

Overexpression of mC4 decreased membrane capacitance without altering overall excitability. by Ashley L. Comer (8299128)

Response of I_Ca,L to IBMX in WT and AMPKα2-/- mice AVMs. by Anne Garnier (130125)

Subjects:

Image 1_Exploration of the diagnostic and prognostic roles of decreased autoantibodies in lung cancer.tif by Ying Ye (72583)

Distinct effects on calcium channel activation of <i>CACNA1I</i> disease-associated amino acid substitutions A398E/V and M1425V/I. by Yousra El Ghaleb (22075892)

All-cause gastroenteritis hospitalisations of children decreased after the introduction of rotavirus vaccine in Stockholm by Selma Olsson-Åkefeldt (11500789)

Image_1_Electroencephalographic Evidence for Individual Neural Inertia in Mice That Decreases With Time.JPEG by Andrzej Z. Wasilczuk (11945885)

“…EEG was measured after induction of and emergence from isoflurane administered near the EC₅₀ dose for loss of righting in genetically inbred mice on a timescale that minimizes pharmacokinetic confounds. …”

Image_1_Decreased Systemic and Airway Sirtuin 1 Expression in Adults With Bronchiectasis.TIF by Xiao-rong Han (8470563)