Showing 301 - 320 results of 18,916 for search '(( 50 ((we decrease) OR (a decrease)) ) OR ( 10 ((nm decrease) OR (nn decrease)) ))', query time: 0.64s Refine Results
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    DataSheet_1_IL-40: A New B Cell-Associated Cytokine Up-Regulated in Rheumatoid Arthritis Decreases Following the Rituximab Therapy and Correlates With Disease Activity, Autoantibod... by Adela Navrátilová (11589532)

    Published 2021
    “…As B cells play a pivotal role in autoimmunity, we investigated the function of IL-40 in rheumatoid arthritis (RA).…”
  6. 306

    Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

    Published 2024
    “…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”
  7. 307

    Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

    Published 2024
    “…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”
  8. 308

    Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

    Published 2024
    “…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”
  9. 309

    Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

    Published 2024
    “…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”
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    High resolution structures visible with the 25 nm zone plate objective. by Kamal L. Nahas (13014698)

    Published 2022
    “…<p>139 CryoSXT tomograms were recorded from 107 cells using a 25 nm zone plate objective and several structures that were unrelated to HSV-1 infection were observed, including some that were not visible using the 40 nm zone plate objective. …”
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    Supramolecular DNA Photonic Hydrogels for On-Demand Control of Coloration with High Spatial and Temporal Resolution by Yixiao Dong (2174902)

    Published 2021
    “…We solve this problem by creating a DNA hydrogel system that shows a 50 000-fold decrease in modulus upon heating by ∼10 °C. …”
  18. 318

    Supramolecular DNA Photonic Hydrogels for On-Demand Control of Coloration with High Spatial and Temporal Resolution by Yixiao Dong (2174902)

    Published 2021
    “…We solve this problem by creating a DNA hydrogel system that shows a 50 000-fold decrease in modulus upon heating by ∼10 °C. …”
  19. 319

    Supramolecular DNA Photonic Hydrogels for On-Demand Control of Coloration with High Spatial and Temporal Resolution by Yixiao Dong (2174902)

    Published 2021
    “…We solve this problem by creating a DNA hydrogel system that shows a 50 000-fold decrease in modulus upon heating by ∼10 °C. …”
  20. 320

    Supramolecular DNA Photonic Hydrogels for On-Demand Control of Coloration with High Spatial and Temporal Resolution by Yixiao Dong (2174902)

    Published 2021
    “…We solve this problem by creating a DNA hydrogel system that shows a 50 000-fold decrease in modulus upon heating by ∼10 °C. …”