image2_Myostatin Promotes Osteoclastogenesis by Regulating Ccdc50 Gene Expression and RANKL-Induced NF-κB and MAPK Pathways.tif by Xin Zhi (1829224)

“…Specifically, myostatin increased the phosphorylation of Smad2, which led to the activation of NF-κB and MAPK pathways to activate osteoclastogenesis. Ccdc50 was identified as a gene whose expression was highly decreased in osteoclastogenesis upon myostatin treatment, and it could inhibit the function of myostatin in osteoclastogenesis by blocking NF-κB and MAPKs pathways. …”

<i>fshr-1</i> mutants have decreased synaptic vesicle release accompanied by accumulation of some synaptic vesicle and active zone proteins. by Morgan Buckley (20291334)

Down-regulation of Rfng and overexpression of Lfng or Mfng decreased their ability to promote Th2 subsets but elevated the ability to promote Th1 subsets. by Wen Gu (129075)

Standardized mean effect differences between wet-lab experiment and model simulations. by Rachael Miller Neilan (10678614)

“…<p>Hedges’ <i>g</i> standardized mean effect differences were calculated between different groups from our wet-lab experiments and three models (60:40, 50:50, and 30:70) which differed based on the PKC<i>δ</i>:SOM ratio. …”

The expression of <i>Collagen II</i> and <i>Collagen X</i> in cartilage cells were significantly decreased after siRNA treatment. by Fei Ye (339913)

<i>glr-1</i> mRNA and GLR-1::GFP levels are not decreased in <i>ces-1</i> loss-of-function mutants. by Lidia Park (3146751)

Leptin decreases NPY mRNA and increases POMC mRNA in rats on a CHOW diet, but not in rats on a fcHFHS diet. by José K. van den Heuvel (518005)

Peritonitis model of inflammatory response to immune complexes shows that RLS-0071 (also known as PIC1) inhibits MPO activity and decreases NETosis. by Adrianne Enos (4523560)

Effect of AE on Aβ-increased phosphorylation of IRS-1-Ser307 and Tau, and Aβ-decreased phosphorylation of GSK-3β. by Chien-Ning Huang (1739806)

Decreased expression of <i>TLR4</i>, <i>TLR21</i> and <i>TLR2-1</i> genes in susceptible chickens. by Zhongyong Gou (329295)

EWAT phospho-ACC (Ser79), phospho-AMPKα (Thr172) and phospho-PPARγ (Ser273) were decreased in LBW. by Ousseynou Sarr (577782)

Systemic administration of rAAV6-μDys enhances the structural properties of EDL muscles in dystrophic mice. by Joshua Park (719780)

<i>Nrf2</i> expression in <i>Hesr1</i>/<i>Hesr3</i>-double null primary myoblasts is decreased. by Masahiko Yamaguchi (801411)

Fluorofenidone decreased p22^phox expression in the kidney of <i>db/db</i> mice at earlier stages of DN development. by Xuan Xiong (649607)

Distribution of mean ∑PAHs (ng‧L⁻¹) in water samples from various watersheds: areas surrounding TP (a), areas surrounding China (b), and areas around the worl... by Xinyu Wen (3693)

Adiposity is increased and osteoblast-occupied bone surface is decreased within the external fracture callus during late stage healing in HFD-fed mice. by Matthew L. Brown (431187)

Systemic administration of rAAV6-μDys improves some functional properties of EDL muscles in dystrophic mice. by Joshua Park (719780)

Serum estradiol concentrations in study (n = 9) and control (n = 5) bitches during the luteal phase, from days 8 to 27 after the estimated LH peak. by Kamil Kacprzak (713647)

Protein-protein interaction modeling reveals a putative CXCL10 binding site on GP63 that closely approximates the GP63 active site and CXCL10 cleavage site. by Alejandro L. Antonia (7147739)

“…(C) The mean Zdock score, an energy-based scoring function, is plotted for the top 10 model predictions for each condition. …”

Serum progesterone concentrations in study (n = 9) and control (n = 5) bitches during the luteal phase, from days 8 to 27 after the estimated LH peak. by Kamil Kacprzak (713647)