Mutational scanning of autologous virus. by Collin Joyce (16469212)

“…The top panel shows fold increase/decrease while the bottom shows IC₅₀ (μg/ml). …”

Image_1_Mesenchymal Stem Cell Secretion of SDF-1α Modulates Endothelial Function in Dilated Cardiomyopathy.JPEG by Courtney Premer (7420643)

“…SDF-1α and plasma TNFα negatively correlated with EPC-CFUs in both treatment groups (R = −0.7, P = 0.0004). ECs treated with 20 ng SDF-1α expressed lower levels of TNFα mRNA than cells treated with 100 ng (0.7 ± 0.2 vs. 2.1 ± 0.3, P = 0.0008). …”

Effect of replacing beef fat with safflower oil on physicochemical, nutritional and oxidative stability characteristics of wieners by Emel KAYNAKCI (10463779)

“…Incorporation of SO increased CIE L* and b* values, whereas it caused a decrease in CIE a* values of wieners (P < 0.05). …”

Label-free real-time multi-parametric monitoring enables high content analysis. by Heinz-Georg Jahnke (122745)

“…The effect on the APD was determined for one hour after doxorubicin application and revealed a concentration dependent response with an EC₅₀ value of 17 µM (n  = 3 hCMC), (B) The impedance analysis revealed a concentration- and time-dependent decrease where IC₅₀ values could be determined for each time point (n  = 5 hCMC). …”

Proliferation and demyelination in the early stages after crush injury. by Anna Henzi (9635793)

“…Scale bar: 50 μM. (b) Ki67-proliferation index (% ki67-positive nuclei) as quantified from IF images was highest at 5 d.p.c. and decreased at later stages post crush injury. …”

Supplementary file 1_Modulatory effects of transcranial direct current stimulation on sensory gating in Fibromyalgia Syndrome.docx by Juan L. Terrasa (5506691)

“…</p>Results<p>Whereas P50 and N100 components were unaltered, a significant modulatory effect on the difference S1 – S2-which is commonly considered an index of sensory gating-in the Late Positive Complex component was found. …”

Inhibitory effect of FGF10 on Graves′ orbitopathy (GO) and non-GO orbital fibroblasts. by Sun Young Jang (7252301)

“…<p>After treatment with 100 ng/mL of rhFGF10 for 0, 6, 24, and 48 h, fibronectin, collagen IIIa (COL3A) and collagen Iα (COL1A) protein expression was significantly decreased at 24 h or 48 h. …”

Kinases are recruited to the signaling complex by alternative N-t localization domains. by Paloma M. Sato (672126)

“…In most cases, mutations that disrupt specific recruitment interactions decrease pathway activation between 40%–50%. MUT Ste20[N]-Ste50[C] might still localize to the signaling complex, as Ste50's RA domain binds Cdc42 independently of Ste20's PBD domain <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002012#pbio.1002012-Truckses1" target="_blank">[53]</a>. …”

CRT silencing improved FZD-induced injury of mitochondria and cardiomyocytes. by Ming Zhang (9736)

“…When transfected NRCMs were stimulated with 50 µM FZD for 24 h, real-time PCR revealed that CRT silencing significantly inhibited the decrease of MnSOD mRNA expression (E), and western blot was used to determine the protein levels of CRT, phosphorylated and total STAT3, and MnSOD in the whole cell lysates. β-actin was used as a loading control. …”

Tau knockout prevents sensitivity to Kainic acid–mediated stress in AICD-Tg mice. by Kaushik Ghosal (244754)

“…*p<0.05, **p<0.01, ***p<0.001, one way ANOVA (all data expressed as Mean ± SEM). n = 5 for all groups (D-G). Scale bar = 50 μm (D) and100 μm (F).…”

Datasheet1_Polynitroxylated PEGylated hemoglobin protects pig brain neocortical gray and white matter after traumatic brain injury and hemorrhagic shock.pdf by Jun Wang (5906)

“…The number of cortical neuron long dendrites enriched in microtubules (length >50 microns) decreased in neocortex by 41 ± 24% after LR resuscitation but was not significantly changed after PNPH resuscitation. …”

Table 1_Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings.do... by Mostafa M. Rady (14004633)

“…<p>Abiotic stress significantly damages crops, reducing global yields by over 50%. Among these challenges, salt stress poses a critical constraint that severely affects the growth, productivity, and quality of soybeans in various regions worldwide. …”

Changes in human intervertebral disc biochemical composition and bony end plates between middle and old age by Delio Eulalio Martins (5759282)

“…</p><p>Results</p><p>The old-aged group showed a decrease in content of sulphated and non-sulphated glycosaminoglycans relative to middle-aged and there were also alterations in the proportion of GAG disaccharides and a decrease of collagen fiber size. …”

Donor and Geometry Optimization: Fresh Perspectives for the Design of Polyoxometalate Charge Transfer Chromophores by Bethany R. Hood (20396768)

Brivanib inhibits liver fibrosis induced by thioacetamide. by Ikuo Nakamura (548298)

“…(B) The number of bands of bridging fibrosis per high power field were counted in images obtained at 100× magnification after Sirius red staining. There was a significant decrease in the number of bands in both the 25 mg/kg and 50 mg/kg brivanib groups, compared to placebo. …”

Collagen XVI overexpression leads to an increase of ILK/kindlin-1 interaction. by Konstanze B. Bedal (513309)

“…<p>(<b>A</b>) Proximity ligation assay for the analysis of ILK/kindlin-1 interaction in COLXVI and mock control cells (scale bar equals 50 µm). …”

The effect of dopamine on Δψ_m and [Ca²⁺]_c in midbrain neurons and astrocytes. by Sonia Gandhi (49260)

“…Furthermore this increase in [Ca²⁺]_c is associated with a reduction in ΔΨ_m. Application of 50 mM KCl induces a further rise in [Ca²⁺]_c and profound mitochondrial depolarisation. …”

Hv1 increases colorectal cell migration and invasion. by Yifan Wang (380120)

“…Down-regulation Hv1 expression by siRNA or inhibition of Hv1 activity by 100 µM ZnCl₂ clearly decrease the migratory ability of the highly metastatic SW620 cells. …”

Histopathological lesions in SFTSV-Infected humanized mice. by Shijie Xu (3324546)

“…Areas of interest (AOI) are enlarged, and quantitative graphs are presented at the right. (A) Decreased cellularity and obvious lymphocyte depletion in the red pulp (RP) of the spleen at sacrificed day. …”

8oxoG inhibits TRF1 binding to telomeric DNA by Patricia L. Opresko (7493)

“…Substrates (2.5 nM) were incubated alone (−) or together with decreasing concentrations of purified TRF1 (200, 100, 50 or 25 nM) (lanes 2–5, 7–10, and 12–15, 17–20, 22–25 and 27–30) for 20 min at 4°C in TEL buffer. …”