Active compounds screened from TFDM. by Xu Hu (23350)

“…</p><p>Results</p><p>21 active components were screened, 158 potential drug targets for the prevention and treatment of CIRI were obtained, 53 main targets were further screened in the protein-protein interaction network, and 106 signal pathways, 76 biological processes, 26 cell components and 50 molecular functions were enriched (P<0.05). Through the compound-target-pathway network, the key compounds that play a role in the prevention and treatment of CIRI, such as acacetin, apigenin and other flavonoids, as well as the corresponding key targets and key signal pathways, such as AKT1, SRC and EGFR were obtained. …”

Network of compound-target-pathway. by Xu Hu (23350)

“…</p><p>Results</p><p>21 active components were screened, 158 potential drug targets for the prevention and treatment of CIRI were obtained, 53 main targets were further screened in the protein-protein interaction network, and 106 signal pathways, 76 biological processes, 26 cell components and 50 molecular functions were enriched (P<0.05). Through the compound-target-pathway network, the key compounds that play a role in the prevention and treatment of CIRI, such as acacetin, apigenin and other flavonoids, as well as the corresponding key targets and key signal pathways, such as AKT1, SRC and EGFR were obtained. …”

Results of the PSA for the difference versus no screening (number of referrals to TVS and number of diagnosed VP cases). by Benjamin Ruban-Fell (10791208)

Iron elevation and adipose tissue remodeling in the epididymal depot of a mouse model of polygenic obesity by Xiaoya Ma (536145)

Supplementary Material for: Endovascular thrombectomy with or without bridging thrombolysis in acute ischemic stroke: A cost-effectiveness analysis by Morsi R.Z. (17739816)

“…Background There is unclear added benefit of intravenous thrombolysis (IVT) with endovascular thrombectomy (EVT). We performed a cost-effectiveness analysis to assess the cost-effectiveness comparing EVT with IVT versus EVT alone. …”

Climate and seed size of a dry forest species: influence on seed production, physiological quality, and tolerance to abiotic stresses by Samara Elizabeth Vieira Gomes (4718994)

“…The predicted increase in temperature will not impair germination, however, the time available for seedling establishment will decrease due to lacking rainfall. The increase in the amount of small-sized seeds produced in drought years is a strategy for coping with harsh environments, rather than a decrease in seed quality.…”

Serum lipoxin A4 (LXA4) and resolvin D1 (RvD1) deficiency in patients with sleep-disordered breathing. by Yung-Che Chen (381913)

“…<p>(A) Serum RvD1 and (B) LXA4 levels were both decreased in patients with primary snoring (PS), treatment-naïve OSA, and severe OSA on CPAP treatment as compared with that in the healthy subjects (HS). …”

Clinical effectiveness and cost-effectiveness as a function of PrEP adherence, HIV prevalence and behavioral disinhibition. by Anders Chen (640309)

Image_1_Efficacy and safety of Iguratimod as an add-on therapy for refractory lupus nephritis: A preliminary investigational study.pdf by Qingran Yan (637573)

“…The CRR rate was 42.3% (11/26) at month 6. With a median follow-up of 52 weeks (range: 23-116 weeks), the CRR rate at the last visit was 50% (13/26) and 73.1% (19/26) of patients had UPCR decrease of over 50%. …”

Effect of TritonX-100 on the mAbs binding to purified lung ACE. A-C. by Sergei M. Danilov (118956)

“…The coloring is as in the legend to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0209861#pone.0209861.g002" target="_blank">Fig 2</a>, and, in addition, values decreased more than by 50% are highlighted in deep blue.…”

The effect of cPTIO pre-treatment on cell death rate. by Bushra Ijaz (4353385)

“…<p>Cell death rate as measured in tolerant (a) and sensitive (b) cell cultures after 50uM cPTIO pre-treatment and 100 and 150mM NaCl stress. …”

FPR1/2/3 expressions of human monocytic THP-1 cells exposed to normoxia (NOX), 2 days of persistent hypoxia (PH), or 2 days of intermittent hypoxia with re-oxygenation (IHR). by Yung-Che Chen (381913)

“…<p>The box plots show the 25th, 50th, 75th percentiles, maximum, and minimum. IHR treatment resulted in increased (A) FPR1 and (B) FPR2 expressions on M2a cells. …”

The in vitro and in vivo effect of a chemokine inhibitor CTCE-9908 in combination with Kynurenine metabolites on tumour adhesion by Danielle Tatchum (16946574)

“…In the non-cancerous cell lines HaCaT and EA. hy926, there was a decrease in percentage cell number after treatment with L-kyn, phorbol 12-myristate 13-acetate (PMA), a positive control for adhesion, and CTCE-9908, suggesting a decrease in cell adhesion in the non-cancerous cell lines.…”

DataSheet_1_A comparison of rat models that best mimic immune-driven preeclampsia in humans.pdf by Fahmida Jahan (17057388)

“…Of the three rodent models tested, we found that Poly I:C and LPS decreased both fetal weight and survival; and correlated with a reduction in region specific placenta growth. …”

Use of Anti-Retroviral Therapy in Tuberculosis Patients on Second-Line Anti-TB Regimens: A Systematic Review by Matthew Arentz (122414)

“…These associations remained significant in patients with a CD4 less than 200 cells/mm³ and less than 50 cells/mm³, and when correcting for drug resistance pattern.…”

Formyl peptide receptor (FPR) 1/2/3 expressions of blood innate immune cells in patients with sleep disordered breathing and healthy subject without snoring. by Yung-Che Chen (381913)

“…(E) Decreased FPR3 expression of M2a monocyte in treatment-naïve OSA versus HS group. …”

Agonistic activity of tamoxifen, a selective estrogen-receptor modulator (SERM), on arthritic ovariectomized mice by L.A.S. Silva (4617988)

“…<div><p>Arthritis is positively associated with the decline of sex hormones, especially estrogen. Tamoxifen (TMX) is a selective estrogen receptor modulator, possessing agonist or antagonistic activity in different tissues. …”

<i>Tg(slc17a6b)</i>-positive pretectal neurons are required for AF7 formation. by Alexandra R. Schmidt (18452108)

“…The ablated RPr showed statistically significant decreases in <i>slc17a6b-positive</i> neurons compared to LPr side (n = 7), <i>t</i>(13) = 0.96, <i>p</i><0.001. …”

Cardiorespiratory/sedative effects of a peptide identified in crotalic venom compared to acepromazine and xylazine in horses by C. J. X. Abimussi (16562532)

“…Six mares, aged 8 years and weighing 415kg underwent three different treatments in a crossover design: TA (acepromazine: 50μg.kg-1), TC (crotalphine: 0.01μg.kg-1) and TX (xylazine: 1000μg.kg-1), intravenously. …”

SOX2⁺ cells act as a glial progenitor <i>in vivo</i>. by Jorge Oliver-De La Cruz (573045)

“…<p><b>A–B</b>. After the spontaneous differentiation protocol of small spheres, the number of SOX2⁺ cells decreased, accompanied by the emergence of O4⁺ cell processes, which correspond to 58.35% ±21.11% of total cells. …”