Toxicological Effects of the Different Substances in Tobacco Smoke on Human Embryonic Development by a Systems Chemo-Biology Approach by Bruno César Feltes (407939)

“…Our analysis showed a relationship between nicotine and 50 additional harmful substances involved in a variety of biological process that can cause abnormal proliferation, impaired cell differentiation, and increased oxidative stress. …”

Table1_A capillary flow-driven microfluidic device for point-of-care blood plasma separation.DOCX by William Brakewood (14189291)

“…The impact of input sample hematocrit percentage on flow rate through the device was also examined, with samples with hematocrits greater than 45% decreasing plasma flow rate. Lastly, we evaluated the ability of this device to produce plasma with a high protein concentration and found no significant difference between protein levels in samples from the device compared to samples produced via centrifugation. …”

The Number of Patients and Events Required to Limit the Risk of Overestimation of Intervention Effects in Meta-Analysis—A Simulation Study by Kristian Thorlund (149383)

“…For each scenario, we calculated the probability of observing overestimates of RRR>20% and RRR>30% for each cumulative 500 patients and 50 events. …”

Gene set enrichment analysis revealed NF-κB signaling as a potential downstream regulator of Efp. by Wataru Sato (149080)

Table_7_The m6A methylation landscape, molecular characterization and clinical relevance in prostate adenocarcinoma.docx by Chao Li (145513)

DataSheet_1_The Efficacy and Safety of Probiotics for Allergic Rhinitis: A Systematic Review and Meta-Analysis.pdf by Chao Luo (343569)

Sensitivity analysis reveals a unique contribution for all damage mechanisms, but simulated tissue is most sensitive to oxygen. by Cordelia Ziraldo (221649)

Structure–Activity Relationships of Neplanocin A Analogues as <i>S</i>‑Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities by Girish Chandra (1309602)

“…In this study, 6′-fluoroneplanocin A (<b>2</b>) was the most potent inhibitor of AdoHcy hydrolase (IC₅₀ = 0.24 μM). …”

p75^NTR small molecule ligands protect neurons from Aβ-induced death. by Tao Yang (184280)

“…<p>6–7 DIV hippocampal, cortical and septal neurons were exposed to: culture medium alone (CM); CM containing 10 µM Aβ(S), a control peptide containing Aβ(1-42) residues in a scrambled sequence; 10 µM Aβ alone or with NGF (100 ng/ml , ∼4 nM), LM11A-24, -31, or -36 (100 nM). …”

Incidence and relative risk of stroke in the diabetic and the non-diabetic population between 1998 and 2014: A community-based stroke register by Andrea Icks (282944)

What Is Needed to Eradicate Lymphatic Filariasis? A Model-Based Assessment on the Impact of Scaling Up Mass Drug Administration Programs by Randee J. Kastner (811800)

Table_1_A gaming app developed for vestibular rehabilitation improves the accuracy of performance and engagement with exercises.DOCX by Linda J. D’Silva (17444991)

“…Vestibular rehabilitation is the gold standard recommendation to decrease symptoms and improve postural stability. The Clinical Practice Guidelines for vestibular hypofunction suggest home exercises 3–5 times daily, but patient adherence is a problem, with compliance rates often below 50%.…”

Data_Sheet_2_A Link Between Methylglyoxal and Heart Failure During HIV-1 Infection.XLSX by Prasanta K. Dash (5258294)

“…Histopathological and biochemical analyses of cardiac tissues from Hu-mice 17 weeks post-infection affirmed MG increase with a concomitant decrease in expression of the MG-degrading enzyme glyoxalase-1 (Glo1). …”

Data_Sheet_1_A Link Between Methylglyoxal and Heart Failure During HIV-1 Infection.PDF by Prasanta K. Dash (5258294)

“…Histopathological and biochemical analyses of cardiac tissues from Hu-mice 17 weeks post-infection affirmed MG increase with a concomitant decrease in expression of the MG-degrading enzyme glyoxalase-1 (Glo1). …”

Data Sheet 1_Efficacy and safety of Tanshinone capsule in Acne vulgaris: a systematic review and meta-analysis.docx by Yutong Deng (20908982)

“…We found that Tanshinone capsules can reduce acne recurrence rates [risk ratio (RR) 0.44, 95% confidence interval (CI): 0.34 to 0.57, p < 0.00001]; downregulate levels of necrosis factor-alpha (TNF-α) [ mean difference (MD) 0.44, −10.18, 95% CI: −13.57 to −8.04, p < 0.00001], interleukin (IL) 4 (MD -6.46, 95%CI: −7.14 to −5.77, p < 0.00001), IL-6 (MD -16.14, 95%CI: −30.10 to −2.18, p = 0.02), IL-8 (MD -4.48, 95%CI: −8.30 to −0.65, p = 0.02) and testosterone (MD -14.50, 95%CI: −17.59 to −11.40, p < 0.00001); lower Global Acne Grading System (GAGS) score (MD -4.71, 95%CI: −7.62 to −1.80, p = 0.002); decrease sebum secretion rates (MD -0.29, 95%CI: −0.49 to −0.10, p = 0.003), but the regulation of Luteinizing hormone (LH), Follicle-stimulating hormone (FSH), Estradiol (E₂) is not obvious. …”

Presentation_1_Pressure changes in the endotracheal tube cuff in otorhinolaryngologic surgery: a prospective observational study.pdf by Sujung Park (5999498)

“…</p>Conclusion<p>In otorhinolaryngologic surgery, cuff pressure increased or decreased outside the appropriate range due to various factors. …”

Quantum Mechanical Enhancement of Rate Constants and Kinetic Isotope Effects for Water-Mediated Proton Transfer in a Model Biological System by James W. Mazzuca (3664111)

“…Deuteration of the donor and acceptor proton are shown to decrease the reaction rate constant by a factor of 50, and this is another indicator that tunneling plays an important role in this proton transfer mechanism.…”

Quantum Mechanical Enhancement of Rate Constants and Kinetic Isotope Effects for Water-Mediated Proton Transfer in a Model Biological System by James W. Mazzuca (3664111)

“…Deuteration of the donor and acceptor proton are shown to decrease the reaction rate constant by a factor of 50, and this is another indicator that tunneling plays an important role in this proton transfer mechanism.…”

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic by Aaron Mobley (412870)

“…We found that ∼50% of respondents had experienced at least one episode of the inability to reproduce published data; many who pursued this issue with the original authors were never able to identify the reason for the lack of reproducibility; some were even met with a less than “collegial” interaction.…”

Biochar Decelerates Soil Organic Nitrogen Cycling but Stimulates Soil Nitrification in a Temperate Arable Field Trial by Judith Prommer (517077)

“…We found that biochar increased total soil organic carbon but decreased the extractable organic C pool and soil nitrate. …”