IDN5706 reduces phosphorylation in S2448 of mTOR. by Viviana A. Cavieres (500139)

Efficacy and Acceptability of Glycemic Control of Glucagon-Like Peptide-1 Receptor Agonists among Type 2 Diabetes: A Systematic Review and Network Meta-Analysis by Zhixia Li (2736331)

“…Dulaglutide, exenatide long-acting release (exe_lar), liraglutide and taspoglutide had significant lowering effect when compared with sitagliptin (HbA1c<7.0%) and insulin (HbA1c<6.5%). Finally, according to SUCRAs, placebo, thiazolidinediones and albiglutide had the best decrease effect on hypoglycemia; sulphanylureas, sitagliptin and insulin decrease the incidence of treatment discontinuation most; exe_lar and dulaglutide had the highest impact on glycemic level among 13 treatments.…”

Effects of IDN5706 on APP turnover at the ER. by Viviana A. Cavieres (500139)

Expression of selected genes at PG and PV stages in <i>bmp15</i> mutant. by Yue Zhai (3141960)

Changes in neuronal morphology after 150 nM sAPP-Fc added to 5DIV neurons. by Stéphanie Chasseigneaux (231744)

“…<p>Morphometric analysis 96 hours after the addition of 150 nM sAPP-Fc to 5DIV neurons shows that: (<b>A</b>) sAPP-Fc induces a significant decrease of primary dendrite number (control (Ctrl) vs sAPP-Fc: p<0.0276). …”

Highest potential mean-to-standard deviation ratio (MSDR) for each single outcome measure at different weightings with all possible weight combinations of the other metrics. by Stanley Lambertus (3779344)

Apoptosis is enhanced in DCE- or CS-treated keratinocytes. by Claudia Scarponi (205759)

Effect of partial Glo-I inhibition by EP on LPS-induced production of TNF-α, collagen-I and α-SMA in HSC. by Marcus Hollenbach (376231)

“…Presence of LPS and treatment with low-level concentrations of MGO (indicating partial inhibition of Glo-I activity without complete enzyme inhibition) showed significant decrease of LPS-induced release of TNF-α (absence vs. presence of 10mM MGO: 371.8±22.7 vs. 60.9±11.2 pg/ml; p<0.001), collagen-I (10.0±0.3 vs. 1.8±0.5 ng/ml; p<0.001) and α-SMA (68.6±3.6 vs. 43.8±2.2 ng/ml; p<0.001) <b>(A2, B2, C2)</b>. …”

Activity of 7DW8-5 on DCs and <i>i</i>NKT cells in rhesus macaques. by Neal N. Padte (476908)

“…Each column indicates the mean value for 5 animals per group; errors bars denote SEM. * = p < 0.05 and ** = p <0.01 when compared to control group receiving AdPfCA + 0 µg 7DW8-5. …”

Anatomical confirmation of drug injection sites. by Diana Amorim (662998)

“…Limb withdrawal threshold is presented as mean + SEM. (**<i>P</i><0.01, t-test for paired data). gf—gram force.…”

Diannexin (DA5) reduces leukocyte influx 3 days after I/R. by Kimberley E. Wever (180536)

“…(C) When compared to vehicle-treated mice, leukocyte influx in renal tissue of DA5-treated mice was decreased on day 3 after IRI induction. …”

Intra- & Inter-assay Variance for the flow cytometric analysis of STAT5Ptyr in human peripheral blood monocytes. by Erin Garrigan (473998)

“…However, this significant difference decreased to 5.4-fold at 48 hr (*p = 0.013), due to the increased inter-assay variability seen in control samples after storage.…”

Hel2 and Asc1 attenuate gene expression from stall-containing mRNAs only at high initiation rates. by Heungwon Park (3859507)

IDN5706 inhibits proteolytic processing of APP to CTFs, and production of Aβ species. by Viviana A. Cavieres (500139)

IDN5706 reduces the levels of EDEM1 in a time-dependent manner. by Viviana A. Cavieres (500139)

Working model for REG-O3 mechanism of action. by Rodrick Montjean (400649)

Both WD and AD shift OD in the binocular V1 in fully adult mice. by Manuel Teichert (6443960)

“…<p>(<b>a, b</b>) V1 activity evoked by visual stimulation of the contra or ipsilateral eye in untreated control mice (n = 5) remained unchanged at 0, 3 and 7 days. …”

Table_5_Mycobiome of Fraxinus excelsior With Different Phenotypic Susceptibility to Ash Dieback.docx by Marta Agostinelli (10268201)

Attenuation of CDK expression and cyclin D-CDK4/6 activity by androgen in PC3-Lenti-AR. by Young-Chae Kim (163381)

“…(E) In comparison to control samples, DHT treatment for 24 hours significantly decreased CDK4 and CDK6 mRNAs and pre-mRNAs 1.5 fold or more and increased CDKN1A mRNA and pre-mRNA 2 fold or more, suggesting AR-mediated regulation of transcription at these genes, n = 3. …”

SILD increases renal expression of TEMs pro-angiogenic macrophages. by Mary Anna Venneri (737094)