Table_3_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Introduction<p>The differentiation of B cells into antibody-secreting plasma cells depends on cell division-coupled, epigenetic and other cellular processes that are incompletely understood.</p>Methods<p>We have developed a CRISPR/Cas9-based screen that models an early stage of T cell-dependent plasma cell differentiation and measures B cell survival or proliferation versus the formation of CD138+ plasmablasts. …”

Evaluation of a Dengue NS1 Antigen Detection Assay Sensitivity and Specificity for the Diagnosis of Acute Dengue Virus Infection by Laura L. Hermann (638244)

“…We found significant variation in the sensitivity of the InBios NS1 ELISA kit depending on the serotype of the dengue virus and also found decreasing sensitivity the longer after the onset of illness, showing 100% sensitivity early during illness, but dropping below 50% by Day 7.…”

Table_2_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Introduction<p>The differentiation of B cells into antibody-secreting plasma cells depends on cell division-coupled, epigenetic and other cellular processes that are incompletely understood.</p>Methods<p>We have developed a CRISPR/Cas9-based screen that models an early stage of T cell-dependent plasma cell differentiation and measures B cell survival or proliferation versus the formation of CD138+ plasmablasts. …”

Table_4_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Introduction<p>The differentiation of B cells into antibody-secreting plasma cells depends on cell division-coupled, epigenetic and other cellular processes that are incompletely understood.</p>Methods<p>We have developed a CRISPR/Cas9-based screen that models an early stage of T cell-dependent plasma cell differentiation and measures B cell survival or proliferation versus the formation of CD138+ plasmablasts. …”

Table_1_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Introduction<p>The differentiation of B cells into antibody-secreting plasma cells depends on cell division-coupled, epigenetic and other cellular processes that are incompletely understood.</p>Methods<p>We have developed a CRISPR/Cas9-based screen that models an early stage of T cell-dependent plasma cell differentiation and measures B cell survival or proliferation versus the formation of CD138+ plasmablasts. …”

Table_1_Tipping point of plant functional traits of Leymus chinensis to nitrogen addition in a temperate grassland.DOCX by Guojiao Yang (12158151)

“…However, it remains unclear whether there are critical transitions or tipping points for the response of plant growth or traits to N enrichment, and how these responses differ to different N forms. We chose the native, perennial clonal grass, Leymus chinensis in Inner Mongolia steppe, and conducted a field experiment, in which six N addition rates (0, 2, 5, 10, 20, and 50 g N m^–2 year^–1) and five N compound types [NH₄NO₃, (NH₄)₂SO₄, NH₄HCO₃, CO(NH₂)₂, slow-release CO(NH₂)₂] are considered. …”

Data_Sheet_1_Aging and hypertension in kidney function decline: A 10 year population-based study.DOCX by David A. Jaques (13913718)

“…Multivariate linear regressions were used with KFD as the outcome and age as the main predictor. HT was tested as a modifying factor.</p>Results<p>We included 4,163 participants with mean age 52.2 ± 10.4, 44.7% men, 31.9% HT, and 5.0% diabetics. …”

Data_Sheet_1_Causal Relationship Between Parathyroid Hormone and the Risk of Osteoarthritis: A Mendelian Randomization Study.docx by Guiwu Huang (11183319)

“…</p>Conclusion<p>MR analysis supported a potential causative relationship between decreased serum circulating PTH and a higher risk of hip and knee OA.…”

Table_1_Prevalence and effect on survival of pre-treatment sarcopenia in patients with hematological malignancies: a meta-analysis.doc by Jianzhu Xiong (17106295)

“…Background & aims<p>Evidence regarding the prevalence of pre-treatment sarcopenia and its impact on survival in patients with hematological malignancies (HM) varies across studies. We conducted a systematic review and meta-analysis to summarize this discrepancy.…”

Data_Sheet_1_Causal Association Between Tea Consumption and Bone Health: A Mendelian Randomization Study.docx by Song Chen (69646)

“…To determine the causal relationship between genetically predicted tea intake and OA, RA, and OP, we performed a two-sample Mendelian randomization (MR) study based on large samples.…”

Laboratory Diagnostics Market in East Africa: A Survey of Test Types, Test Availability, and Test Prices in Kampala, Uganda by Lee F. Schroeder (356832)

“…This is especially true in resource-limited settings such as sub-Saharan Africa. We present a first-of-its-kind report of diagnostic test types, availability, and prices in Kampala, Uganda.…”

Table_1_Predictive Value of Geriatric Nutritional Risk Index in Patients With Coronary Artery Disease: A Meta-Analysis.pdf by Yu Fan (111503)

Supplementary Material for: Assessment of the Corticospinal Tract Profile in Pure Lower Motor Neuron Disease: A Diffusion Tensor Imaging Study by Sarica A. (7851320)

Inhibition of Enterovirus 71 (EV-71) Infections by a Novel Antiviral Peptide Derived from EV-71 Capsid Protein VP1 by Chee Wah Tan (167218)

“…The <em>in vitro</em> inhibitory effect of SP40 exhibited a dose dependent concentration corresponding to a decrease in infectious viral particles, total viral RNA and the levels of VP1 protein. …”

Table_1_The Groove Enhancement Machine (GEM): A Multi-Person Adaptive Metronome to Manipulate Sensorimotor Synchronization and Subjective Enjoyment.DOCX by Lauren K. Fink (12875291)

“…In predicting enjoyment, we found an interaction between auditory feedback and metronome adaptivity, with increased enjoyment at optimal levels of adaptivity only with auditory feedback and a severe decrease in enjoyment at higher levels of adaptivity, especially without feedback. …”

Data_Sheet_1_The influence of precipitation timing and amount on soil microbial community in a temperate desert ecosystem.pdf by Yao Xiao (227567)

“…The study included five precipitation pattern treatments: a control group (C), as well as groups receiving 50 and 100% of the local mean annual precipitation amount (145 mm) during either the early growing season (E50 and E100) or the late growing season (L50 and L100). …”

A role for <i>bmm</i> function in the somatic cells of the gonad in the regulation of whole-body triglyceride storage and breakdown in males. by Lianna W. Wat (8339454)

“…(I–K) Using an LD-GFP, we found that a subset of the LipidTOX-positive lipid droplets in the testis (arrowheads) represent droplets in the somatic cells of the gonad. …”

Analysis of host and interferon-induced responses in glucose/galactose infected with vaccinia virus. by Tyron Chang (9922533)

Table_1_The responses of soil microbial characteristics to nitrogen addition and biochar amendment in a Larix kaempferi plantation.docx by Chen Hu (317374)

“…However, the impacts of biochar on the microbial characteristics of soil after short-term N deposition in subtropical plantations remain poorly understood. Here, we investigated the effects of biochar application (0, 5, 10 t ha⁻¹) on soil chemical traits and microbial characteristics (extracellular enzyme activities, microbial community and microbial biomass) in a Larix kaempferi plantation in Shennongjia, China, under N addition (0, 50, 100 kg N ha⁻¹ yr⁻¹) during two growing seasons. …”

Identification of Chalcones as <i>Fasciola hepatica</i> Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach by Florencia Ferraro (3146766)

“…One of the compounds, <b>C34</b>, tightly bounds to juvenile specific <i>Fh</i>CL3 with an IC₅₀ of 5.6 μM. We demonstrated that <b>C34</b> is a slow-reversible inhibitor that interacts with the Cys-His catalytic dyad and key S₂ and S₃ pocket residues, determinants of the substrate specificity of this family of cysteine proteases. …”