The Proteasome as a Drug Target in the Metazoan Pathogen, <i>Schistosoma mansoni</i> by Betsaida Bibo-Verdugo (4273624)

“…After 24 h, bortezomib and carfilzomib decreased worm motility by more than 85% and endogenous proteasome activity by >75%, and after 72 h, they increased caspase activity by >4.5-fold. …”

The Proteasome as a Drug Target in the Metazoan Pathogen, <i>Schistosoma mansoni</i> by Betsaida Bibo-Verdugo (4273624)

“…After 24 h, bortezomib and carfilzomib decreased worm motility by more than 85% and endogenous proteasome activity by >75%, and after 72 h, they increased caspase activity by >4.5-fold. …”

Total neutrophil and total macrophage concentrations for inflammatory mediator inhibition at different time points. by Sridevi Nagaraja (833270)

“…We simulated chronic inflammation by increasing the initial platelet concentration by 100 fold, increasing the macrophage influx rate parameter by 1.5 fold, and simultaneously decreasing the platelet degradation rate parameter by 1.5 fold. …”

Table_1_Correlation of HBV DNA and Hepatitis B Surface Antigen Levels With Tumor Response, Liver Function and Immunological Indicators in Liver Cancer Patients With HBV Infection U... by Shida Pan (12696593)

Sleep deprivation by payam saidie (20329440)

“…Furthermore, in the NSP group, a significant decrease was observed at BASE compared to 60 min-PS (P ≤ 0.05) (20.72%).…”

Erk and PI3K signal patterns determine Myc temporal behaviors. by Tae Lee (42532)

National Land Cover Database (NLCD) Tree Canopy Cover (TCC) Puerto Rico USVI by U.S. Forest Service (17476914)

“…Data for this record includes the following resources:</div><ul><li> <a href="https://www.arcgis.com/sharing/rest/content/items/50ad050c2cd44598a9bee2b4990de85e/info/metadata/metadata.xml?…”

Figure 2 by Kazuo Konishi (195884)

“…<p>A) DNA methylation status of thirteen cancer-specific or age-related genes/CpG islands in 16 primary CRCs and matched liver metastasis. …”

Mitochondrial fatty acid uptake and complex IV inhibition by palmitoylcarnitine in early type-2 diabetic hearts. by Phing-How Lou (198977)

“…Complex IV inhibition is given as relative decrease in oxygen consumption. IC₅₀, concentration of palmitoylcarnitine that reduces the respiration rate by 50%. …”

Model for active compensation by feedback and shared regulation. by Pétra Vande Zande (17628246)

Stratification to predict the response to antioxidant by Cristiane Ritter (296603)

Evaluation of anionic surfactant removal by anaerobic degradation of commercial laundry wastewater and domestic sewage by Clara Vieira de Faria (4682032)

“…The reactor was operated in three stages, all under mesophilic conditions and with a hydraulic retention time of 36 h. At stage I, the laundry wastewater was diluted with tap water (influent: 15.3 ± 4.9 mg LAS/L); at stage II, 50% of the feed volume was domestic sewage and 50% was a mixture of tap water and laundry wastewater (influent: 15.8 ± 4.9 mg LAS/L); and at stage III, only domestic sewage was used as a diluent of the laundry wastewater (influent: 24.1 ± 4.1 mg LAS/L). …”

Description analysis of the main variables. by Li Siyao (18510148)

Oct4 actively enhances the proliferation of ATSC cells along with the overexpression of pluripotency related genes and telomerase activation. by Jung Hwan Kim (259298)

Caddisfly biodiversity in Pernambuco state, Brazil: overcoming the biodiversity knowledge shortfall and insights into the effects of climate change by Rafael Pereira (6635264)

“…Climate projections indicate a significant decrease in the temperature range, shifting from the current 13.2–33.6 °C to 17.9–33.6 °C, and precipitation range will decrease from 507 to 1948 mm³/year to 528–1428 mm³/year. …”

Curcumin boosts activities of endogenous enzymatic antioxidants that were depleted with chronic iron overload. by Farid A. Badria (448269)

“…<p><b>A, B)</b> Fold change in catalase (CAT) activity (U/g tissue) in liver and spleen relative to that of normal control, which was assigned a value of 1; <b>C, D)</b> Fold change in Superoxide dismutase (SOD) activity (U/g tissue) in liver and spleen relative to that of normal control which was assigned a value of 1. …”

Table_1_Synergistic Antibacterial Activity of Designed Trp-Containing Antibacterial Peptides in Combination With Antibiotics Against Multidrug-Resistant Staphylococcus epidermidis.... by Dejing Shang (8037545)

“…Among the antibiotics that we studied, penicillin, ampicillin and erythromycin showed a distinct synergistic effect in combination with all of the Trp-containing AMPs, represented by a fractional inhibitory concentration index (FICI) of <0.5. The antibacterial activities were noticeably improved, with 32-to 64-fold reductions in the MIC values for ampicillin and 16- to 32-fold reductions in the MIC values for erythromycin and penicillin. …”

Image_2_Synergistic Antibacterial Activity of Designed Trp-Containing Antibacterial Peptides in Combination With Antibiotics Against Multidrug-Resistant Staphylococcus epidermidis.... by Dejing Shang (8037545)

“…Among the antibiotics that we studied, penicillin, ampicillin and erythromycin showed a distinct synergistic effect in combination with all of the Trp-containing AMPs, represented by a fractional inhibitory concentration index (FICI) of <0.5. The antibacterial activities were noticeably improved, with 32-to 64-fold reductions in the MIC values for ampicillin and 16- to 32-fold reductions in the MIC values for erythromycin and penicillin. …”

Image_4_Synergistic Antibacterial Activity of Designed Trp-Containing Antibacterial Peptides in Combination With Antibiotics Against Multidrug-Resistant Staphylococcus epidermidis.... by Dejing Shang (8037545)

“…Among the antibiotics that we studied, penicillin, ampicillin and erythromycin showed a distinct synergistic effect in combination with all of the Trp-containing AMPs, represented by a fractional inhibitory concentration index (FICI) of <0.5. The antibacterial activities were noticeably improved, with 32-to 64-fold reductions in the MIC values for ampicillin and 16- to 32-fold reductions in the MIC values for erythromycin and penicillin. …”

Image_3_Synergistic Antibacterial Activity of Designed Trp-Containing Antibacterial Peptides in Combination With Antibiotics Against Multidrug-Resistant Staphylococcus epidermidis.... by Dejing Shang (8037545)

“…Among the antibiotics that we studied, penicillin, ampicillin and erythromycin showed a distinct synergistic effect in combination with all of the Trp-containing AMPs, represented by a fractional inhibitory concentration index (FICI) of <0.5. The antibacterial activities were noticeably improved, with 32-to 64-fold reductions in the MIC values for ampicillin and 16- to 32-fold reductions in the MIC values for erythromycin and penicillin. …”