Effect of dexmedetomidine (5 μg∙kg⁻¹ or 50 μg∙kg⁻¹) at experimental recording (Protocol 1). by Yoichiro Kitajima (4319455)

Subjects:

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Activation of axonal GABA_A receptors decreases AP-induced Ca²⁺ transients. by Yang Xia (104600)

“…<p>A, Left, projection of 2-photon fluorescence images of a recorded pyramidal neuron filled with Alexa Fluor 594 (50 µM) and OGB-1 (200 µM). …”

Decreased MRPS34 levels cause a reduction in mitochondrial protein synthesis and steady state levels of mitochondrial proteins. by Tara R. Richman (713532)

Mean sediment transport (g m^-2 day^-1) by grazing condition (Grazed, Some Graze, and No Graze). by Andrew Kulmatiski (833256)

Predicted mean number (trend) of all sand flies and <i>Phlebotomus spp</i>. sand flies in the intervention site pre- and post- intervention using negative binomial regression, Taya... by Samer Sawalha (5890535)

Loss of primary cilia and decreased nephron number in mice with Tamoxifen-induced <i>Kif3a</i> deficiency. by Lijun Chi (196000)

“…(H) Quantitation of the number of cells with a primary cilium. Tamoxifen administration to <i>Kif3a™</i> embryos decreases cilia number by approximately 50% in both ureteric and metanephric mesenchyme cells (***, P<0.001). …”

Chromosomal Translocations in the Parasite <i>Leishmania</i> by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism by Marie-Claude N. Laffitte (669627)

“…Attempts to generate <i>RAD50</i> null mutants in a wild-type background failed and we provide evidence that this gene is essential. …”

<i>Nf1</i> OPG mice exhibit decreased hole poking in response to a novel holeboard apparatus. by David F. Wozniak (78177)

“…(C) <i>Nf1</i> OPG mice also showed a trend toward decreased general ambulatory activity although this difference was also not significant (p = 0.053). …”

Decreased aqueous humor outflow rate in sGCα₁^−/− mice. A by Emmanuel S. Buys (392112)

A homozygous missense variant in <i>VWA2</i>, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux by Amelie T. van der Ven (4782093)

“…We identified a homozygous missense mutation (c.1336C>T, p.Arg446Cys) in the gene <i>Von Willebrand factor A domain containing 2</i> (<i>VWA2</i>). …”

Electrocardiographic Abnormalities in Hypertension Models by Ana Gabriela Conceição-Vertamatti (8401224)

Activation of hippocampal granule and pyramidal neurons by ambiguously conditioned cues is altered in mice lacking adult neurogenesis. by Lucas R. Glover (3912628)

Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism - Fig 3 by Qing-Yun Guo (2007082)

The flavanone homoeriodictyol increases SGLT-1-mediated glucose uptake but decreases serotonin release in differentiated Caco-2 cells - Fig 3 by Barbara Lieder (3743008)