Functional metabolism pathways present at ≥ 0.5% mean relative abundance in Control calves (n = 15) and High-Se treatment calves (n = 15) after weaning (baseline; week 0), at the e... by Jean A. Hall (289030)

Effect of contamination on animal food-contact zone and their types after porcine epidemic diarrhea virus (PEDV) inoculated animal food manufacturing^†. by Loni L. Schumacher (3666775)

Effect of different doses of FA-SnO₂ NPs (50 mg/kg for group B, 100 mg/kg for group C and 200 mg/kg for group D) on biochemical profiling of the tested male Wistar rats... by Demiana H. Hanna (11512956)

Effect of different doses of FA-SnO₂ NPs (50 mg/kg for group B, 100 mg/kg for group C and 200 mg/kg for group D) on hematological parameters of the tested male Wistar ra... by Demiana H. Hanna (11512956)

Stable overexpression of PFKFB3-5 in HEK-293 and U87 cells leads to decreased cell viability and proliferation while leaving transcriptional profile of PFKFB3-1 and -11 unaltered. by Ulli Heydasch (11091062)

Diet composition of porcine epidemic diarrhea virus (PEDV) inoculated animal food, as fed basis. by Loni L. Schumacher (3666775)

TG6-44 treatment decreases IFN-β levels in A/X31-infected THP-1 cells. by Juan A. De La Cruz (11154187)

Layout of research facility. by Loni L. Schumacher (3666775)

Number of pulmonary endothelial cells decreased upon infection and started to proliferate during resolution to restore their number by 15 dpi accompanied by decreased endothelial a... by Emilie Pollenus (10147748)

The involvement of ERK5 in fluvastatin-induced Nrf2 signaling in VSMCs. by Ae-Rang Hwang (4040408)

Figure S2: Depletion of RASSF1A alone or with RASSF1C results in disappearance of tight junctions and decrease of adherens junction, replaced by diffuse adherent junctions. from RA... by Fatéméh Dubois (5846192)

Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases by Xiao Li (107004)

“…In this study, we first identified several hit compounds against CARM1 by structure-based virtual screening (IC₅₀ = 35.51 ± 6.68 to 68.70 ± 8.12 μM) and then carried out chemical structural optimizations, leading to six compounds with significantly improved activities targeting CARM1 (IC₅₀ = 18 ± 2 to 107 ± 6 nM). …”

Estimation of Purkinje neurons in mid-sagittal slices of the cerebellum of control and <i>Giardia intestinalis</i> parasitized gerbils by Cresyl violet staining (Normal) and the TU... by Angélica González Maciel (18946369)

IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors by Alexandra Cousido-Siah (777034)

“…Next, by means of IC₅₀ measurements, X-ray crystallography, WaterMap analysis, and advanced binding free energy calculations with a quantum-mechanical (QM) approach, we have studied their structure–activity relationship (SAR) against both enzymes. …”

Gene clustering identifies up- and down-regulated groups that control development, pluripotency, and cell division. by Michael Shelton (382572)

“…<p>Pluripotent H9 hESCs were differentiated for 50 days as previously described [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0222946#pone.0222946.ref012" target="_blank">12</a>], beginning with high (7.5 μM or 10 μM) CHIR99021 concentrations. mRNA samples from the indicated time points were subjected to gene expression profiling. …”

<i>M</i>. <i>leprae</i> was detected in the liver of a multibacillary patient and can decrease ApoA-I expression in HepG2 cells. by Robertha Mariana R. Lemes (8635935)

DN Rab1 and Rab8 decrease plasma membrane expression of KCa3.1 in polarized epithelia. by Claudia A. Bertuccio (309866)

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... by Hiroyuki Koami (3878434)

“…</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …”

Flow diagram of the study. by Yoonjee Cho (15453454)

“…A total of 162 patients were included. The SOFA score on POD 5 was significantly higher in the High-decrease group compared with the Low-decrease group (5.2 ± 2.6 vs. 4.1 ± 2.3; mean difference: 1.1, 95% CI: 0.3 to 1.8; P = 0.005). …”

Baseline characteristics of patients. by Yoonjee Cho (15453454)

“…A total of 162 patients were included. The SOFA score on POD 5 was significantly higher in the High-decrease group compared with the Low-decrease group (5.2 ± 2.6 vs. 4.1 ± 2.3; mean difference: 1.1, 95% CI: 0.3 to 1.8; P = 0.005). …”