Section A represents a randomised trial of IL6RA therapy with both normal IL-6 signalling and the effect of intervention. by Fergus W. Hamilton (10724401)

Overexpression of miR-129-5p alleviated the depressive-like phenotypes of CRS and LPS treated mice. by Qiaozhen Qin (13159201)

Neuronal cell cultures derived from embryos injected with APPb-MO had decreased neurite length. by Ping Song (169215)

“…The neurons from the embryos injected with 8 ng of APPb-MO showed a decrease in neurite length compared to neurons from the control embryos (un-injected). …”

Analysis of parasites expressing ddFKBPmyc-Rab5A(N158I) and ddFKBPmyc-Rab5C(N153I). by Katrin Kremer (386602)

Supplementary Material for: Inverse and Direct Cancer Comorbidity in People with Central Nervous System Disorders: A Meta-Analysis of Cancer Incidence in 577,013 Participants of 50... by Catalá-López F. (4142920)

“…<b><i>Results:</i></b> The presence of CNS disorders was associated with a reduced co-occurrence of cancer (ES = 0.92; 95% confidence interval, CI: 0.87-0.98; I² = 94.5%). …”

Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α_1A-Adrenoceptor Antagonists by Fei Zhao (183673)

“…In this study, two highly selective and potent α_1A-AR antagonists, compounds (<i>R</i>)-<b>14r</b> (IC₅₀ = 2.7 nM, α_1B/α_1A = 640.1, α_1D/α_1A = 408.2) and (<i>R</i>)-<b>23l</b> (IC₅₀ = 1.9 nM, α_1B/α_1A = 1506, α_1D/α_1A = 249.6), which exhibited similar activities and better selectivities in cell-based calcium assays as compared with the marketed drug silodosin (IC₅₀ = 1.9 nM, α_1B/α_1A = 285.9, α_1D/α_1A = 14.4), were identified. …”

CD4 and CCR5 utilization efficiency of individual virus. by Yiying Zhang (198443)

R₇-fused peptides inhibit FMDV production in BHK-21 cells. by Mónica González-Magaldi (638526)

Effect of <i>bipA</i> deletion on biofilm formation in <i>E. coli</i> and <i>S</i>. Typhimurium. by Eunsil Choi (8271039)

Adjusted analyses of the odds of a child aged 6–59 months being anaemic in Cambodia (N = 10,051). by Samnang Um (14990562)

(A) FC and VIP bubble plots of the Model.vs.SHR; (B) Hierarchical clustering results of differential metabolites in the Model.vs.SHR (only the top 50 metabolites with the highest V... by Xiao Zhang (152326)

Lysosome function, as assessed by Lamp1 levels, are unchanged in the <i>GBA1</i> D409V KI mouse model. by Nicole K. Polinski (10947787)

Introduction of the D409V point mutation to the <i>GBA1</i> gene does not affect <i>GBA1</i> mRNA transcription or GCase protein translation. by Nicole K. Polinski (10947787)

Western blot experiments demonstrating that TGF-β1 decreases CFTR protein abundance in HBE cells. by Steven M. Snodgrass (587391)

“…(<b>B</b>) Representative experiment demonstrating that TGF-β1 decreases WCL CFTR in a time-dependent manner. TGF-β1 (15 ng/ml) or vehicle control (CTRL) was added to the basolateral medium and cells were incubated for 24 h. …”

Excel spreadsheet containing, in separate sheets (for each figure), the underlying numerical datas for Figure panels 1A, 1B, 1C, 2B, 3A, 3B, 3C, 4C, 4D, 4E, 4F, 4G, 5B, 8C and 8D. by Acharya Balkrishna (5640038)

Bubble plots showing differences in the proportions of bacterial taxa as a percentage of the entire bacteria population detected during consumption of 5.0 g (A) and 10.0 g (B) when... by Lauren M. G. Davis (275267)

Multiple agents are able to induce CLL B cell differentiation and subsequent decrease in LEF-1 expression. by Albert Gutierrez Jr. (342562)

Supplementing 5% PEG increases the end-to-end flow-stretched DNA length and reduces fluctuations. by Fatema Tuz Zohra (11378812)

Association of SDOH scores with attitudes, practices and mental health outcomes among Arkansans overall and by race and ethnicity ^a^,^b^,<s... by Jenil R. Patel (3639451)

Population dynamics modeling of split^50cM <i>ClvR</i> V1 drive introduced at different release percentages, and an example illustrating the role that LOF alleles play in... by Georg Oberhofer (3401438)

“…A large number of individuals WT at each of these loci is now introduced into the modified population (release of 50%). …”