Data Sheet 1_Efficacy and safety of Tanshinone capsule in Acne vulgaris: a systematic review and meta-analysis.docx by Yutong Deng (20908982)

“…We found that Tanshinone capsules can reduce acne recurrence rates [risk ratio (RR) 0.44, 95% confidence interval (CI): 0.34 to 0.57, p < 0.00001]; downregulate levels of necrosis factor-alpha (TNF-α) [ mean difference (MD) 0.44, −10.18, 95% CI: −13.57 to −8.04, p < 0.00001], interleukin (IL) 4 (MD -6.46, 95%CI: −7.14 to −5.77, p < 0.00001), IL-6 (MD -16.14, 95%CI: −30.10 to −2.18, p = 0.02), IL-8 (MD -4.48, 95%CI: −8.30 to −0.65, p = 0.02) and testosterone (MD -14.50, 95%CI: −17.59 to −11.40, p < 0.00001); lower Global Acne Grading System (GAGS) score (MD -4.71, 95%CI: −7.62 to −1.80, p = 0.002); decrease sebum secretion rates (MD -0.29, 95%CI: −0.49 to −0.10, p = 0.003), but the regulation of Luteinizing hormone (LH), Follicle-stimulating hormone (FSH), Estradiol (E₂) is not obvious. …”

The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review by Sarah Elshahat (8587107)

“…Mean EuroQol-5D index scores ranged from 0.80 to 0.86 for CKD stages 1–3, and decreased to 0.73–0.79 for CKD stages 4–5. …”

Micro RNAs expression analysis of right atrial biopsies from AF patients compared to controls (SR). by Joana Larupa Santos (8822501)

Results of the DSA for the number of referrals to TVS. by Benjamin Ruban-Fell (10791208)

Iron elevation and adipose tissue remodeling in the epididymal depot of a mouse model of polygenic obesity by Xiaoya Ma (536145)

Results of the DSA for the number of diagnosed VP cases. by Benjamin Ruban-Fell (10791208)

Docking results of effective compounds in TFDM. by Xu Hu (23350)

“…</p><p>Results</p><p>21 active components were screened, 158 potential drug targets for the prevention and treatment of CIRI were obtained, 53 main targets were further screened in the protein-protein interaction network, and 106 signal pathways, 76 biological processes, 26 cell components and 50 molecular functions were enriched (P<0.05). Through the compound-target-pathway network, the key compounds that play a role in the prevention and treatment of CIRI, such as acacetin, apigenin and other flavonoids, as well as the corresponding key targets and key signal pathways, such as AKT1, SRC and EGFR were obtained. …”

Active compounds screened from TFDM. by Xu Hu (23350)

“…</p><p>Results</p><p>21 active components were screened, 158 potential drug targets for the prevention and treatment of CIRI were obtained, 53 main targets were further screened in the protein-protein interaction network, and 106 signal pathways, 76 biological processes, 26 cell components and 50 molecular functions were enriched (P<0.05). Through the compound-target-pathway network, the key compounds that play a role in the prevention and treatment of CIRI, such as acacetin, apigenin and other flavonoids, as well as the corresponding key targets and key signal pathways, such as AKT1, SRC and EGFR were obtained. …”

Network of compound-target-pathway. by Xu Hu (23350)

“…</p><p>Results</p><p>21 active components were screened, 158 potential drug targets for the prevention and treatment of CIRI were obtained, 53 main targets were further screened in the protein-protein interaction network, and 106 signal pathways, 76 biological processes, 26 cell components and 50 molecular functions were enriched (P<0.05). Through the compound-target-pathway network, the key compounds that play a role in the prevention and treatment of CIRI, such as acacetin, apigenin and other flavonoids, as well as the corresponding key targets and key signal pathways, such as AKT1, SRC and EGFR were obtained. …”

ERDRP-0519 potently inhibits <i>de novo</i> RNA synthesis. by Robert M. Cox (8029568)

“…<p><b>A-F)</b> Purified recombinant WT MeV L-P complexes or complexes harboring the L_T776A or L_H589Y resistance mutations were incubated with either a 16-nt RNA template (A) and the represented NTPs to assess <i>de novo</i> RNA synthesis or a 16-nt RNA template (B), a 5’-phosphorylated 4-nt primer, and the represented NTPs to assess primer extension. …”

Results of the PSA for the difference versus no screening (number of referrals to TVS and number of diagnosed VP cases). by Benjamin Ruban-Fell (10791208)

Supplementary Material for: Endovascular thrombectomy with or without bridging thrombolysis in acute ischemic stroke: A cost-effectiveness analysis by Morsi R.Z. (17739816)

“…Background There is unclear added benefit of intravenous thrombolysis (IVT) with endovascular thrombectomy (EVT). We performed a cost-effectiveness analysis to assess the cost-effectiveness comparing EVT with IVT versus EVT alone. …”

Climate and seed size of a dry forest species: influence on seed production, physiological quality, and tolerance to abiotic stresses by Samara Elizabeth Vieira Gomes (4718994)

“…The predicted increase in temperature will not impair germination, however, the time available for seedling establishment will decrease due to lacking rainfall. The increase in the amount of small-sized seeds produced in drought years is a strategy for coping with harsh environments, rather than a decrease in seed quality.…”

Clinical effectiveness and cost-effectiveness as a function of PrEP adherence, HIV prevalence and behavioral disinhibition. by Anders Chen (640309)

Serum lipoxin A4 (LXA4) and resolvin D1 (RvD1) deficiency in patients with sleep-disordered breathing. by Yung-Che Chen (381913)

“…<p>(A) Serum RvD1 and (B) LXA4 levels were both decreased in patients with primary snoring (PS), treatment-naïve OSA, and severe OSA on CPAP treatment as compared with that in the healthy subjects (HS). …”

Mapping the properties of cells in relation to their local neighborhood. by Matthew French (13007466)

“…<b>D:</b> Heightened TBXT and TBX6 CV to the NMP region and decreases into the mesodermal PS. Lines indicate the fit of a non-parametric multiple regression curve and shading indicates 0.05 and 0.95 confidence intervals calculated as (mean ± 1.96 * (<i>σ</i>/(√<i>n</i>)). …”

Image_1_Efficacy and safety of Iguratimod as an add-on therapy for refractory lupus nephritis: A preliminary investigational study.pdf by Qingran Yan (637573)

“…The CRR rate was 42.3% (11/26) at month 6. With a median follow-up of 52 weeks (range: 23-116 weeks), the CRR rate at the last visit was 50% (13/26) and 73.1% (19/26) of patients had UPCR decrease of over 50%. …”

Involvement of the BMP pathway. by Pascale Plaisancié (13531638)

TMS recapitulates epigenetic age predictions and tissue-dependent effects identified via other technologies. by Amy Longtin (21409957)

Debt maturity, financial crisis and corporate performance in GCC countries: A dynamic-GMM approach by Zeitun, Rami

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