Supplemental Movies Paulo Caldas PhD thesis by Paulo Caldas (7883579)

“…Increasing concentrations of ZapA progressively increased the thickness of the FtsZ filament bundles and decreased its curvature. …”

SWR-associated increase in neuronal firing rates is weakened in APP/PS1 mice in both dCA1 and vCA1. by Udaysankar Chockanathan (18510288)

“…(M) In vCA1, the SWR log₁₀(modulation index) was significantly decreased in APP/PS1 mice relative to C57BL/6 controls (mean ± std: C57BL/6 = 3.50 ± 1.49, APP/PS1 = 2.28 ± 1.70 Hz, p < 10⁻⁶, two-sided Wilcoxon rank-sum test, n_C57BL/6 = 689 neurons, n_APP/PS1 = 651 neurons).…”

Chronic hyperpolarization of dFB^23E10Ո^84C10 neurons promotes sleep and impairs sleep homeostasis. by Joseph D. Jones (13883524)

“…<p><b>(A)</b> Box plots of total sleep (in minutes) for control and <i>dFB-Split>Kir2.1</i> female flies. …”

<i>Foxo</i> mediates the effects of <i>PI3K</i> on motor neuron excitability. by Eric Howlett (268817)

“…For all LTF experiments, the bath solution contained 0.15 mM [Ca²⁺] and 100 µM quinidine. A) Representative traces showing the decreased rate of onset of LTF (I) and decreased ejp amplitude (II) in <i>Foxo²¹/Foxo²⁵</i> larvae compared to wildtype at the indicated [Ca²⁺], and the increased rate of onset of LTF and ejp amplitude in larvae overexpressing <i>Foxo</i>. …”

C2CD3 regulates spatial organization of centriole architecture. by Eloïse Bertiaux (5309927)

“…For CEP162-positive centrioles: siCTRL = 100% ± 0, siC2CD3 = 50.83% ± 4.31. Overall CEP162 fluorescence decreased in siC2CD3 (<i>n</i> = 31, 1.47 ± 0.39 AU.) vs. siCTRL (<i>n</i> = 35, 1.68 ± 0.51 AU), unpaired <i>t</i> test *** <i>P</i> value = 0.0008. …”

Single-cell-resolution analysis of RPE flatmounts revealed only minor changes to cellular morphology. by Viola Kretschmer (485828)

“…Analysis of cell size revealed a modest increase in cell size in the mutant starting from P29 onwards, while AR was decreasing. …”

C2CD3 is crucial for the localization of the LDR and DISCO complexes. by Eloïse Bertiaux (5309927)

“…<p><b>(A)</b> Expanded centrioles from control (siCTRL) and C2CD3-depleted (siC2CD3) cells stained for C2CD3 (green) and tubulin (magenta). …”