DataSheet_1_Icanbelimod (CBP-307), a next-generation Sphingosine-1-phosphate receptor modulator, in healthy men: pharmacokinetics, pharmacodynamics, safety, and tolerability in a r... by Jason Lickliter (18073228)

“…After single-dose 0.5 mg, although a high-fat breakfast versus fasting did not affect maximal decrease, lymphocyte counts tended to be lower after breakfast across most timepoints up to 72 hours. …”

CPI-1612 represses a subset of enhancers which are linked to differentially expressed genes. by Archana Bommi-Reddy (4104961)

“…RNA-seq, H3K27ac ChIP-seq, and ATAC-seq tracks are plotted at the bottom, with H3K27ac and ATAC-seq peaks showing at least a 2-fold decrease marked with a *. The inset shows the differential ATAC-seq peaks in the <i>ELF3</i> enhancer.…”

Raw data. by Guohui Zhao (4668682)

“…Using the YSV dynamic acceleration signal acquisition system and a portable radar speed gun collect data on racket acceleration, stress-strain signals, and ball speed from 15 male athletes. …”

The participants information. by Guohui Zhao (4668682)

“…Using the YSV dynamic acceleration signal acquisition system and a portable radar speed gun collect data on racket acceleration, stress-strain signals, and ball speed from 15 male athletes. …”

A high seroprevalence of antibodies to pertussis toxin among Japanese adults: Qualitative and quantitative analyses by Takumi Moriuchi (4237807)

TBI accelerated extracellular Aβ deposits in the cortex of AD mice that received TBI. by Naoki Tajiri (106215)

“…Immunofluorescence for the detection of extracellular Aβ deposits and MAP2 (Panel C). Scale bars = 50 µm. …”

A low threshold K⁺ current determines the long refractory period. by Javier Nogueira (348174)

“…E) Pair pulses applied at different delays shows a long lasting refractory period. F) As expected for a low threshold K⁺ conductance, refractoriness was shortened after the application of 50 microMolar 4-aminopyridine to the bath.…”

Temporal Sensitivity of Protein Kinase A Activation in Late-Phase Long Term Potentiation by MyungSook Kim (65534)

Evolution of hepatitis A virus seroprevalence among HIV-positive adults in Taiwan by Yu-Lin Lee (4515169)

“…<div><p>Objectives</p><p>The study aimed to describe the seroprevalence of hepatitis A virus (HAV) in HIV-positive adult patients in Taiwan between 2012 and 2016 and to examine the evolution of HAV seroprevalence between 2004–2007 and 2012–2016.…”

Data Sheet 1_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... by Shi-Bing Liang (10200806)

“…Evidence supports the use of TXL plus WM for reducing angina frequency [SMD −2.50, 95% CI (−3.53, −1.48)], improving seattle angina questionnaire scores (P < 0.05), decreasing nitroglycerin dose [SMD −1.63, 95% CI (−2.26, −1.00)], and shortening angina duration [MD −1.50 min/once, 95% CI (−1.98, −1.02)]. …”

Data Sheet 2_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... by Shi-Bing Liang (10200806)

“…Evidence supports the use of TXL plus WM for reducing angina frequency [SMD −2.50, 95% CI (−3.53, −1.48)], improving seattle angina questionnaire scores (P < 0.05), decreasing nitroglycerin dose [SMD −1.63, 95% CI (−2.26, −1.00)], and shortening angina duration [MD −1.50 min/once, 95% CI (−1.98, −1.02)]. …”

Data Sheet 3_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... by Shi-Bing Liang (10200806)

“…Evidence supports the use of TXL plus WM for reducing angina frequency [SMD −2.50, 95% CI (−3.53, −1.48)], improving seattle angina questionnaire scores (P < 0.05), decreasing nitroglycerin dose [SMD −1.63, 95% CI (−2.26, −1.00)], and shortening angina duration [MD −1.50 min/once, 95% CI (−1.98, −1.02)]. …”

Data Sheet 4_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... by Shi-Bing Liang (10200806)

“…Evidence supports the use of TXL plus WM for reducing angina frequency [SMD −2.50, 95% CI (−3.53, −1.48)], improving seattle angina questionnaire scores (P < 0.05), decreasing nitroglycerin dose [SMD −1.63, 95% CI (−2.26, −1.00)], and shortening angina duration [MD −1.50 min/once, 95% CI (−1.98, −1.02)]. …”

Fungal DenA developmental functions are independent of Nedd8 processing activity. by Martin Christmann (280300)

“…(E) Human DEN1 cleaved human Nedd8 C-terminally fused with GFP while <i>A. nidulans</i> DenA did not. Nedd8-GFP substrate was combined with decreasing amounts of recombinant DEN1 or DenA, respectively (8–0.5 µM). …”

Further optimisation and <i>in vitro</i> characterization of influenza A reporter viruses. by Monique I. Spronken (779529)

“…Silent mutations were introduced into the PA packaging region present in the PA CDS (mPR) and the dPR was decreased from 149 to 50 nucleotides (sPR). (B) Virus titres of the wild-type and eGFP reporter viruses based on data from three individually rescued viruses. …”

Efficacy and safety of a single radiofrequency ablation of solid benign non-functioning thyroid nodules by Roberto Cesareo (4676131)

EFFECT OF PHENOL AS A CONTAMINANT ON THE WILD PEARL OYSTER PINCTADA IMBRICATA RADIATA IN QATAR: ECOTOXICOLOGICAL APPROACH AND USE OF OYSTER SHELL STRUCTURE AS A POTENTIAL MITIGATIO... by BARAH, FARAHNAZ GHOLAMREZA

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DataSheet1_Quantification of CYP3A and Drug Transporters Activity in Healthy Young, Healthy Elderly and Chronic Kidney Disease Elderly Patients by a Microdose Cocktail Approach.pdf by Punyabhorn Rattanacheeworn (11447329)

“…AUC and C_max GMR (95%CI) of atorvastatin, another CYP3A substrate, was increased 2.14 (1.52–3.02) fold in healthy elderly and 4.15 (2.98–5.79) fold in elderly patients with CKD, indicating decreased CYP3A activity related to ageing. …”

A COX inhibitor does not prevent the development of tactile allodynia after nerve injury. by Shigeo Hasegawa (249454)

“…Scale bar, 50 µm. B. The COX-1 inhibitor SC-560 (20 nmol/10 µl) administered through a catheter whose tip was positioned near the L5 DRG once daily for 14 days did not suppress the development of nerve injury-induced a decrease in the paw withdrawal threshold of tactile stimulation using von Frey filaments. …”

Cervical Cancer Screening in Partly HPV Vaccinated Cohorts – A Cost-Effectiveness Analysis by Steffie K. Naber (2175986)

“…</p><p>Methods</p><p>We used the MISCAN-Cervix model to determine the optimal screening strategy for a pre-vaccination population and for vaccinated women (~80% decreased risk), assuming a willingness-to-pay of €50,000 per quality-adjusted life year gained. …”