BC CLC-Pred: a freely available web-application for quantitative and qualitative predictions of substance cytotoxicity in relation to human breast cancer cell lines by A.A. Lagunin (810465)

“…The mean accuracies of prediction <i>r</i>², RMSE, Balance Accuracy for the selected (Q)SAR models calculated by 5F CV were 0.599, 0.679 and 0.875, respectively. As a result, BC CLC-Pred provides simultaneous quantitative and qualitative predictions of IC₅₀ and IG₅₀ values for most of the nine breast cancer cell lines, which may be helpful in selecting promising compounds and optimizing lead compounds during the development of new antineoplastic agents against breast cancer.…”

Unique challenges required reassessment and alterations to critical reagents to rescue a neutralizing antibody assay by Blake A Rowe (19589318)

“…</p> <p><b>Results & conclusion:</b> A larger dynamic range, high inhibition and higher drug tolerance were achieved by adding an acid dissociation step to the assay, performing atypical biotin labeling of Drug 1 and switching to a detection target that contained an Fc linker to increase steric hinderance and decrease its binding affinity to Drug 1.…”

Comparison of choroidal thickness in normal eyes and different ocular pathologies in a Brazilian population by Murilo U. Polizelli (10371024)

“…A total of 74 eyes were included in the normal control group, 50 eyes in the nvAMD group, 44 eyes in the DME group and 13 eyes in the high myopia group. …”

CNF1-treated astrocytes provide a more efficient substrate to neuritogenesis and synaptogenesis. by Fiorella Malchiodi-Albedi (326279)

“…The exposure of astrocytes to CNF1 causes a decrease in GFAP staining (A) whereas hippocampal neurons, growing on CNF1-treated astrocytes but in absence of direct CNF1 influence, produce a much more abundant dendritic network, as shown by MAP2 immunolabeling (A,B, bars  = 200 μm). …”

Data and code from: Ecosystem functional response across precipitation extremes in a sagebrush steppe by Andrew Tredennick (99797)

“…</div><div>Goal is to quantify the impact of a 50% increase/decrease of precipitation on:</div><div><br></div><div>* ANPP through time</div><div>* Relationship of ANPP to soil moisture</div><div>* Species composition</div><div><br></div><div><b>Running the code</b><br></div><div><br></div><div>To fully run this code you will need R and a number of R packages.…”

Branching behavior of a N = 10 units network at Trial T (case of strong inhibition = 0.60) by Elif Köksal-Ersöz (20378631)

“…For a medium punishment (50% decrease in gain), this ratio decreases to 1%. …”

Diffusion of saturated hydrocarbons in low density polyethylene (LDPE) films by Asfour, A.-F. A.

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Comparative Proteomic Profiling of 3T3-L1 Adipocyte Differentiation Using SILAC Quantification by Sunkyu Choi (2141545)

Supplementary Material for: Phosphodiesterase-5 Inhibitors and Dementia Risk: A Real-World Study by Gronich N. (18892231)

“…Similar results were obtained in a competing risk analysis, and in a sensitivity analysis in which we restricted the cohort to patients older than 60 years at cohort entry. …”

A Method for Selectively Enriching Microbial DNA from Contaminating Vertebrate Host DNA by George R. Feehery (477312)

“…We report enrichment of DNA samples from human saliva, human blood, a mock malaria-infected blood sample and a black molly fish. …”

Efficacy of inhibition depends on spatial and temporal features of GABA_AR input. by Nicolas Doyon (344567)

“…Note that this is the optimal frequency for activation of a single “test” synapse; optimal input frequency would necessarily decrease as the number of activated synapses increased, although the exact relationship would depend on the spatial distribution of those active synapses (see <b>A</b>) as well as the level of background synaptic activity.…”

The effect of phenotype switching on ILEI expression. by Ken Noguchi (255943)

Diastolic Left Ventricular Function in Relation to Urinary and Serum Collagen Biomarkers in a General Population by Zhen-Yu Zhang (458621)

“…Our objective was to gain insight in serum and urinary biomarkers reflecting collagen turnover and associated with asymptomatic diastolic LV dysfunction. We randomly recruited 782 Flemish (51.3% women; 50.5 years). …”

Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes by François Dion (3990335)

“…Second, in a rat model of metabolic syndrome (Zucker Lepr^fa/fa), chronic kidney disease caused a 50% increased fasting hyperglycemia (p<0.0001) and an exacerbated glycemic response (p<0.0001) during glucose challenge. …”

DataSheet1_Examining the paradoxical effects of kratom: a narrative inquiry.PDF by Kirsten E. Smith (10716529)

Supplementary Material for: Cigarette Smoking and the Risk of Cutaneous Melanoma: A Case-Control Study by Sondermeijer L. (7362845)

“…<b><i>Objective:</i></b> Previous studies regarding cigarette smoking causing a lower risk of melanoma are inconclusive. Here, we re-examined melanoma risk in relation to cigarette smoking in a large, case-control study. …”

<b>Safety evaluation of matrine and its impact as a feed additive on the production performance of piglets</b> by Zhigang Cao (15458561)

“…<p dir="ltr">Our findings imply that the LD50 of matrine in mice was 202.54 mg/kg, and matrine didn’t cause any hazardous effects when administered to rats within the range of 24.5-50 mg/kg for 180 days. …”

Effect of IL-17A, IL-17F or IL-22 on TER of cultured ARPE-19 monolayer. by Ying Chen (9697)

“…Incubation of ARPE-19 monolayers with 50 ng/ml IL-17A or IL-17F induced a gradual decrease of TER, and a significant effect occurred 5 days (p = 0.019, p = 0.045) after stimulation. …”

Table_1_Daily Intake of a Phaseolus vulgaris L. Snack Bar Attenuates Hypertriglyceridemia and Improves Lipid Metabolism-Associated Plasma Proteins in Mexican Women: A Randomized Cl... by Aurea K. Ramírez-Jiménez (12750107)

“…A modest body weight (5%) reduction was also found. …”

Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study by Houssein H., Ayoub

“…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …”
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