Combining stabilizing point mutations from different Env variants produces a hyperstable virus, comb-mut. by Daniel P. Leaman (105329)

“…(<b>B</b>) The relative resistance of comb-mut to ligand-induced infectivity decay is shown as a function of the fold decrease in IC50 after 20 hour pre-incubation relative to 1 hour pre-incubation as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003184#ppat-1003184-g008" target="_blank"><b>Figure 8</b></a>. …”

Effects of rutile-TiO2 nanoparticles on accelerated weathering degradation of poly(Lactic Acid) by Antunes, A.

“…Thermal stability decreased in the presence of TiO2 and a double melting peak was observed for the PLA/TiO2 nanocomposite. …”
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Recombinant 3xK-C100Flag monomer increased longer Aβ peptides. by Joo In Jung (650746)

“…Molecular mass (m/z) of monomeric 3xK-C100Flag for Aβ40 is 4588.43 (calculated m/z: 4589.27), for Aβ42 is 4773.07 (calculated m/z: 4773.51), and for Aβ45 is 5084.52 (calculated m/z: 5086.90). 3xK-C100Flag dimer and trimer showed decreased Aβ levels compared to the monomer. …”

The Effect of Intravenous Immunoglobulin Combined with Corticosteroid on the Progression of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Meta-Analysis by Liang-ping Ye (3370709)

“…<div><p>Background</p><p>Intravenous immunoglobulin (IVIG) treatment is commonly used to treat Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) with controversial therapeutic effect.</p><p>Methods</p><p>We conducted a comprehensive meta-analysis through combining the published eligible studies to evaluate the effectiveness of IVIG on SJS and TEN treatment.…”

Purified recombinant WT-C100Flag dimer and trimer showed reduced Aβ production. by Joo In Jung (650746)

“…Aβ38, Aβ40 and Aβ42 levels decreased in dimer compared to monomer, and the Aβ levels for trimer were under detection limits. …”

Demonstration of a Direct Interaction between β₂-Adrenergic Receptor and Insulin Receptor by BRET and Bioinformatics by Maja Mandić (662591)

“…In heterologous competition assays, a transient increase in the BRET² signal with a subsequent hyperbolical decrease was observed, suggesting higher-order heteromer formation. …”

Phenoxodiol protects against Cisplatin induced neurite toxicity in a PC-12 cell model-2 by Reuben Klein (78663)

“…</p><p></p>XD for 24 hrs then fixed and immunostained for the neuronal marker βIII-tubulin. A) Control cultures showed a large percentage of cells with long neurites, which were also present in B) 100 nM PXD and C) 1 μM PXD. …”

NOS inhibition with LNNA enhances tone in response to intramural pressure changes but not in the presence of a constant pressure. by Katrin Reimann (290872)

“…Note that the vascular diameter at 60 cmH₂O decreased in vessel segments that were exposed to pressure variations but not in vessel segments that were exposed to a constant pressure and that the diameter in Ca²⁺ free solution was similar in both groups. …”

Far-UV CD spectra of pEAβ(3–40) and Aβ(1–40). by Christina Dammers (803567)

“…(a) CD spectra of 25 μM pEAβ(3–40) in 25%, 23%, 22%, 21% and 20% TFE showed a shift from α-helical structure towards β-sheets with decreasing TFE concentrations. …”

DataSheet1_Resveratrol has an Overall Neuroprotective Role in Ischemic Stroke: A Meta-Analysis in Rodents.docx by Jianyang Liu (9632387)

“…In the stratified analysis, a significant decrease of infarct volume and the neurobehavioral score was achieved in resveratrol sub-groups with a dosage of 20–50 mg/kg. …”

Structural and Functional Effect of an Oscillating Electric Field on the Dopamine-D3 Receptor: A Molecular Dynamics Simulation Study by Zohreh Fallah (3342287)

“…Computing the correlation coefficient parameter showed that increasing the field frequency can weaken the interaction between dopamine and D3R and may decrease the Arg128{3.50}-Glu324{6.30} distance. Because of high stability of α helices along the z-direction, applying an oscillating electric field in this direction with an amplitude 10-time higher did not have a considerable effect. …”

Image_1_Molecular mechanisms regulating natural menopause in the female ovary: a study based on transcriptomic data.jpeg by Quan Liu (486219)

“…Increased contents of terminally differentiated HMGB1+ Granulosa and GSTA1+ Granulosa were observed in the ovaries of individuals aged 50-69. Signaling pathway activity analysis indicated a gradual decrease in TGFb and MAPK pathway activity with menopause progression, while p53 pathway activity increased. …”

Western blot analyses of pull-down assays for the whole Rac protein and a Rac effector domain. by Yudai Matsuoka (9986881)

“…<p>The extent of decreased Rac activity in OSC-19 and HOC313 cells was more significant than that in OSC-20 cells and fibroblasts. …”

The correlation between external apical root resorption and electric pulp test responses: a prospective clinical trial by Farnaz YOUNESSIAN (12853367)

Resveratrol reduces PC-3M-MM2 cell viability by increasing apoptosis. <i>A,</i> by Sandeep Sheth (112040)

“…<b><i>C,</i></b> Resveratrol (25 and 50 µM) increased apoptosis of PC-3M-MM2 cells in a time-dependent manner, as determined by Annexin V-FITC and PI staining. …”

Synergistic effects and optimization of nitrogen and phosphorus concentrations on the growth and nutrient uptake of a freshwater Chlorella vulgaris by Alketife, Ahmed M.

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NeoA inhibits cellular adhesion and causes the disassembly of focal adhesions in MDA-MB-231 cells. by Pamela Austin (248283)

“…(C) Cells pre-attached on fibronectin begin to lose adherence between 10 to 25 min after the start of treatment with 6.5 µM NeoA. Scale bar, 50 µm.</p>…”

Datasheet1_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.pdf by Elena Chiappini (304802)

A new family of boost active neutral point clamped inverter topology with reduced switch count by Siddique, Marif Daula

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Data Sheet 1_Honeysuckle extracts as a potential inhibitor of SARS-CoV-2 infection.docx by Ping-Chang Lin (2848379)

“…We performed a cell viability assay, median tissue culture infection dose (TCID₅₀) assay, and qRT‒PCR, and calculated the virus titers using the Reed-Muench method to evaluate the inhibitory effects of aqueous and alcohol HSEs on SARS‒CoV‒2 and explore the possible underlying mechanisms.…”