Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

A long-term "memory" of HIF induction in response to chronic mild decreased oxygen after oxygen normalization-5 by Chandrashekhar D Kamat (60176)

“…<p><b>Copyright information:</b></p><p>Taken from "A long-term "memory" of HIF induction in response to chronic mild decreased oxygen after oxygen normalization"</p><p>BMC Cardiovascular Disorders 2007;7():4-4.…”

Activation of axonal GABA_A receptors decreases AP-induced Ca²⁺ transients. by Yang Xia (104600)

“…<p>A, Left, projection of 2-photon fluorescence images of a recorded pyramidal neuron filled with Alexa Fluor 594 (50 µM) and OGB-1 (200 µM). …”

Decreased MRPS34 levels cause a reduction in mitochondrial protein synthesis and steady state levels of mitochondrial proteins. by Tara R. Richman (713532)

Loss of primary cilia and decreased nephron number in mice with Tamoxifen-induced <i>Kif3a</i> deficiency. by Lijun Chi (196000)

“…(H) Quantitation of the number of cells with a primary cilium. Tamoxifen administration to <i>Kif3a™</i> embryos decreases cilia number by approximately 50% in both ureteric and metanephric mesenchyme cells (***, P<0.001). …”

Chromosomal Translocations in the Parasite <i>Leishmania</i> by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism by Marie-Claude N. Laffitte (669627)

“…Attempts to generate <i>RAD50</i> null mutants in a wild-type background failed and we provide evidence that this gene is essential. …”

A-p50 affects tumor cell survival through inhibition of NF-κB-mediated transcriptional activation by Jing Mi (18654)

“…</p><p>© 2006 The Author(s)</p> () MTT assay of cell viability. Ad-A-p50-infected A549 cells show a significant decrease in cell viability (Ad-A-p50) compared to Ad-siNT-infected cells, = 3–5 per group, = 0.0001. () Hoechst 33342 staining of apoptotic nuclei. …”

<i>Nf1</i> OPG mice exhibit decreased hole poking in response to a novel holeboard apparatus. by David F. Wozniak (78177)

“…(C) <i>Nf1</i> OPG mice also showed a trend toward decreased general ambulatory activity although this difference was also not significant (p = 0.053). …”

Decreased aqueous humor outflow rate in sGCα₁^−/− mice. A by Emmanuel S. Buys (392112)

Targeted point mutation (F639A) in the GluN1 subunit decreases ethanol sensitivity of NMDA receptors. by Carolina R. den Hartog (484817)

A homozygous missense variant in <i>VWA2</i>, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux by Amelie T. van der Ven (4782093)

“…We identified a homozygous missense mutation (c.1336C>T, p.Arg446Cys) in the gene <i>Von Willebrand factor A domain containing 2</i> (<i>VWA2</i>). …”

HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. by Michael Anthony Ruiz (726055)

“…<b>C,D:</b> In HRMECs transfected with EZH2 siRNA in HG, miR-200b and VEGF were not significantly different from HG+control siRNA but decreased compared to NG+control siRNA. In HRMECs transfected with SUZ12 siRNA in HG, miR-200b was significantly increased with decreased levels of VEGF compared to HRMECs transfected with control siRNA, with levels similar to NG+control siRNA. …”

Kat60 lacking the MIT domain or the MIT domain and linker region detectably colocalizes with only a few, if any, microtubules in cells. by Kyle D. Grode (725568)

50% Reduction of dynein perturbs the movement of APP vesicles. by Gary J. Iacobucci (192833)

“…<p>(<b>A</b>) A representative movie montages from a single neuron is shown from a primary neuronal culture expressing APP-YFP in the context of 100% dynein (APP-YFP) or 50% dynein (APP-YFP; robl^K −/+). …”

CHIKV-CZC-LAMP detected <50 PFU CHIKV. by Kyoko Hayashida (281242)

Lipid consumption of epimastigotes supplemented with 10 or 50% FCS. by Miria G. Pereira (212119)

“…Note that in both initial culture conditions, the fluorescence decreases along time in parasites from 10% FCS or 50% FCS. …”

IL-15 decreased early apoptosis of α-GalCer-treated iNKT cells in SLE patients. by Chien-Ya Hsu (11868746)

The pSK_CRISPRi_<i>hla</i> vector can decrease <i>hla</i> expression when induced. by Javiera Norambuena (137228)

Adaptive radiotherapy for locally advanced non-small cell lung cancer, can we predict when and for whom? by Patrick Berkovic (808056)

“…A linear relationship between GTV-T-F1 volume and absolute volume decrease was found for both groups. …”