Image_1_BML-111 Reduces Neuroinflammation and Cognitive Impairment in Mice With Sepsis via the SIRT1/NF-κB Signaling Pathway.TIF by Shangwen Pan (5648291)

“…Boc-2 (50 μg/kg) was administered intracerebroventricularly 30 min before CLP, and EX527 (10 μg) was administered every 2 days for a total of three times before CLP, also intracerebroventricularly. …”

Methodology flow chart. by Sidra Aman Rana (14167473)

“…<div><p>Domestic water availability is intricately linked with a growing population, urbanization, and associated land use/land cover change (LULCC). …”

Ad26.COV2.S vaccination attenuates signatures of complement system activation and coagulation cascade associated with severe COVID-19. by Malika Aid (7303874)

“…<b>(B)</b> Heatmaps of the normalized expression of the leading genes contributing to the enrichment of thrombosis-associated pathways increased by SARS-CoV-2 in sham animals (in green) and decreased in Ad26 vaccinated hamsters (in pink and blue) at 4 dpi. …”

eIF3f regulated rRNA stability through hnRNP K. by Fushi Wen (175725)

“…(D) Silencing of hnRNP K decreased rRNA. Predesigned hnRNP K siRNA (50 nM, Eurogentec) was transfected into MiaPaCa-2 cells using Lipofectamine. rRNA and hnRNP K mRNA fold changes compared to control RNAi cells were assessed by real time RT-PCR after 48 hours. …”

Fig 10 - by Narasimha M. Beeraka (12189587)

“…BT-474 cells with cisplatin/oxaliplatin treatment: expression of FN3K, Nrf2, and Keap1 was not completely declined with cisplatin but NQO1, and HO-1 expression was mitigated at higher concentrations; interestingly, oxaliplatin downregulated the expression of FN3K and Nrf2 consequently mitigated expression of antioxidant proteins such as NQO1 and HO-1. 1-deoxy-1-morpholinofructose (DMF) (dissolved in 50% ethanol), a competitive inhibitor of FN3K, was used as a positive control which could only inhibit ∼10% of total FN3K activity but the FN3K expression was not decreased upon DMF treatment [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0283705#pone.0283705.ref012" target="_blank">12</a>]. …”

Peripheral Blood Proteins Distinguish IPF Patients from Controls by Ivan O Rosas (91093)

“…Every protein level was divided by the geometric mean of values for the same proteins for all patients and log based 2 transformed. …”

Knockdown of IGFBP7 restored the TGF-β1-induced EMT in HRPTECs. by Jun Watanabe (403029)

“…HRPTECs were transfected with control or IGFBP7 siRNAs (25 nM final concentrations) and subsequently stimulated with TGF-β1 (2.5 ng/ml, 48 h). Lowering the expressions of IGFBP7 proteins reduced the TGF-β1-induced α-SMA expression, but failed to restore the TGF-β1-decreased E-cadherin expression. …”

Intrinsic properties of CNNs. by Cathrin B. Canto (3350390)

“…Therefore, values above 1 indicate post-inhibitory rebound, while values lower than 1 indicate a decreased firing rate after the inhibition. The color coding in B-F corresponds to the neurons presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0165887#pone.0165887.g001" target="_blank">Fig 1A</a> (different colours of purple; dots are also encircled), to the neurons presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0165887#pone.0165887.g002" target="_blank">Fig 2B</a> (red, black and blue neuron; crosses are encircled), and finally all morphologically identified neurons presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0165887#pone.0165887.g003" target="_blank">Fig 3</a> (the colours of the dots have the same colour as the reconstructions of the neurons). …”

Supplementary Material for: Atypical Presentation of an Ovarian Yolk Sac Tumor in an 80-Year-Old Woman: A Case Report and Review of the Literature by Maldonado V. (14559080)

Supplementary Figure 1: Antibodies validated for routinely processed tissue unpredictably stain frozen tissue sections by Giorgio Cattoretti (568042)

“…Antigen retrieval (AR) was performed by placing the sections in a 800 ml glass container filled with the retrieval solutions (10 mM EDTA in Tris-buffer pH 8, Merck), irradiate in a household microwave oven at full speed for 8 min, followed by intermittent electromagnetic radiation to maintain constant boiling for 1min., 5 min. or 20 min., and cooling the sections to about 50Co before use. …”

Factors associated to the practice of physical activity by Brazilian workers by Ana Marcia Rodrigues da Silva (6299831)

“…It is a descriptive, analytical, cross-sectional, quantitative study conducted with 82,019,207 workers by means of the National Survey by Household Sample of 2015. …”

The important variables for random forests (RF). by Deokjin Joo (476851)

“…<p>Two measures of accuracy and Gini index were plotted for each variable used for classification with random forests in a rank order from top to bottom. Meaning of abbreviations of shape variables: ProcCoord_5y, Procrustes <i>y</i> coordinate of landmark position 5; ProcCoord_2x, Procrustes <i>x</i> coordinate of landmark position 2; the number represents landmark position as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0077686#pone.0077686.s001" target="_blank">Figure S1</a>. …”

Luminescent Hydrido-Carbonyl Clusters of Rhenium Containing Bridging 1,2-Diazine Ligands by Monica Panigati (1734016)

“…In the case of <b>4a</b>, a blue shift and an increase of the emission intensity were observed upon decreasing the solvent polarity.…”

Effects of miR-31 on cell number, apoptosis and proliferation of ES cell lines. by Bianca Karnuth (542758)

“…<p>(A) miR-31 decreases the proliferation of ES cell lines. Four ES cell lines were transiently transfected with 100 nM miR-31 mimics. …”

Model sensitivity analysis to parameters: <i>k</i>_<i>τ</i>, <i>τ</i>_<i>max</i>, <i>F</i>_<i>p</i>, <i>F</i>_<i>c</i>, <i>K</i><sub><i>r</i... by Dharsan K. Soundarrajan (11632145)

“…<i>e</i>., 50% of a BV of 1.5 μM would simulate a value of 0.75 μM). …”

Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs. by Ignacio E. Schor (120406)

“…S5</a>). Orange boxes mark regions with peaks appearing at 2 h TSA and not further increasing, or even decreasing, at 6 h (MALAT1 peaks). …”

Long-term BRAFi treatment uncouples Wnt-mediated transcription from Wnt-mediated enhancement of apoptosis. by Andy J. Chien (433600)

Survivorship percentage of <i>Ae</i>. <i>aegypti</i> in field tests from eight operational areas at different distances. by Jonathan R. Hernandez (11648426)

Supplemental_Figures_AJPendo by Nathan Winn (11033022)

<b>Changes to plant traits of two functional types across a soil water content gradient in a tropical dry forest impact tree growth rates</b> (Data sheet and R-code) by Ravi Chaturvedi (17312020)