Table_1_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Trichopsistides A and B: Two Highly Oxygenated Pentacyclic Polyketides with Promising Inhibitory Effects on the NF-κB Signaling Pathway from the Fungus <i>Trichoderma koningiopsis<... by Li Feng (77923)

“…Two highly oxygenated pentacyclic polyketides with two new carbon skeletons, trichopsistide A (<b>1</b>) and trichopsistide B (<b>2</b>), were isolated from the plant endophyte <i>Trichoderma koningiopsis</i> WZ-196 derived from the leaf of <i>Rubia podantha</i> Diels. …”

Table_1_Guanidine acetic acid exhibited greater growth performance in younger (13–30 kg) than in older (30–50 kg) lambs under high-concentrate feedlotting pattern.docx by Wen-Juan Li (1444948)

“…In a brief, the results obtained in the present study suggested that GAA (UGAA and CGAA; 1 g/kg DM) could be applied to improve growth performance in younger (13–30 kg) instead of older (30–50 kg) lambs in high-concentrate feedlotting practice.…”

Discovery of PMSA Derivative <b>11</b> as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis <i>In Vitro</i> and <i>In Vivo</i> by Zhihao Chen (513264)

“…Additionally, <b>11</b> blocked the formation of F-action belts and bone resorption in a concentration-dependent manner. Mechanistically, <b>11</b> decreased the expression of genes required for osteoclastogenesis by blocking NFATc1 translocation from the cytoplasm to nucleus. …”

Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO by Qing-Yuan Wang (11571890)

“…The hypothetical biosynthetic pathways for <b>1</b> and <b>2</b> were postulated and were supported by CRISPR/Cas9 genome editing results. Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”

Dietary or gavaged TU-100 and the ginger component decrease enteropooling stimulated by anti-CD3 antibody treatment in specified pathogen free (SPF) and germ free (GF) C57Bl6 mice. by Nobuhiro Ueno (346397)

Spatial patterns of linear regressions of seasonal mean (JJA and MAM) variables to the PC1 of storm track density in JJA by Buwen Dong (557113)

Over expression of hnRNP A1 decreases and hnRNP F increases inclusion of exon 11 of an <i>INSR</i> minigene, whereas knockdown of endogenous hnRNP F and hnRNP A1 has the opposite e... by Indrani Talukdar (195204)

Data Sheet 2_Reducing ocular Demodex using petroleum jelly may alleviate dry eye syndrome, blepharitis, facial dermatoses, ocular and respiratory allergies, and decrease associated... by Diana E. Senior-Fletcher (22090340)

“…Mean yearly issues of anti-allergy and antimicrobial medicines reduced from 15.6 (range 8–25) to 1.8 (range 0–4), representing an 88.5% decrease for Volunteer 1 and from 5.8 (range 3–9) and 14.2 issues (range 9–24) to zero for both Volunteer 2 and Volunteer 13 respectively, representing 100% reductions in prescribing. …”

Data Sheet 1_Reducing ocular Demodex using petroleum jelly may alleviate dry eye syndrome, blepharitis, facial dermatoses, ocular and respiratory allergies, and decrease associated... by Diana E. Senior-Fletcher (22090340)

“…Mean yearly issues of anti-allergy and antimicrobial medicines reduced from 15.6 (range 8–25) to 1.8 (range 0–4), representing an 88.5% decrease for Volunteer 1 and from 5.8 (range 3–9) and 14.2 issues (range 9–24) to zero for both Volunteer 2 and Volunteer 13 respectively, representing 100% reductions in prescribing. …”

Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 by Marta E. Capala (652765)

“…Downregulation of SAM50 also impaired the proliferation and replating capacity of BCR-ABL-expressing cells, again associated with a decreased mitochondrial membrane potential. …”

AdV-ZFP-VEGF administration reduces apoptosis after SCI. by Sarah A. Figley (389639)

“…Values are mean ± SEM, n = 4/sham and injured control groups, n = 5/AdV-eGFP and AdV-ZFP-VEGF groups. …”

Quantitative analyses of Trpm5- and villin-positive cells in the thymus and urethra. by Junpei Yamashita (2583877)

“…Trpm5-positive cells were completely absent in the <i>Skn-1a</i>-/- urethral epithelium (8.0 ± 0.6 cells in wild-type and 0 cells in <i>Skn-1a</i>-/-), and the number of villin-positive cells tended to decrease in <i>Skn-1a</i>-/- mice compared to wild-type mice (57 ± 11 cells in wild-type and 34 ± 0.9 cells in <i>Skn-1a</i>-/-). …”

Rapid degeneration of 5-HT neurons in SERT-Cre^cre/wt Munc18-1^lox/lox mice. by Jacobus J. Dudok (338648)

“…(O) Analysis of the number of 5-HT cell bodies in the sections showed that there is no difference at E16, but at E18 and P2 there is a decrease of 80% to 90% in the number of 5-HT cell bodies in SERT-Cre^cre/wt Munc18-1^lox/lox sections. …”

Effects of ROCK inhibitors H-1152 and Y-27632 on TNF-induced MLC phosphorylation, actin and CL5 reorganization and the fall in TEER. by Paul R. Clark (714064)

Analysis of Research Activity in Gastroenterology: Pancreatitis Is in Real Danger - Fig 2 by Andrea Szentesi (3239193)

Analysis of requirement for MYPT1 expression in TNF-induced MLC phosphorylation and leak. by Paul R. Clark (714064)

5OMV Inhibits HMGB1-Induced Tube Formation in HUVECs. by Wenyue Hou (10203722)

“…Mean values showing significant difference between the HMGB1-treated group and the 5OMV-treated group are denoted by ^# (<i>P</i> < 0.05) or ^## (<i>P</i> < 0.01). …”

LTP modulates steady-state inactivation of A-type K⁺ currents. by Sung-Cherl Jung (261358)

“…Scale bars, 200 pA, 50 ms. The A-current available for activation at −60 mV was significantly decreased only in the neurons receiving paired stimulation 10 min after conditioning stimulation (a red arrow). …”

Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles <i>in vitro</i> - Fig 4 by Remo Campiche (3714208)

“…Hair follicles treated with lower concentrations of Gambogic Amide kept their anagen-like appearance. Bars = 50 μm. <b>E: Immunohistochemical quantification of melanocytes with p16, a marker for mature and senescent melanocytes</b>. …”