The inhibitor U0126 abolishes angiotensin II-dependent reduction of phosphorylated Akt. by Natalia Dünner (465700)

“…<p>(A) Representative Western blot analysis of phosphorylated and total Akt in extracts from cells treated with 1×10⁻⁵ M U0126 for 60 min before exposure to angiotensin II (AII) for additional 60 min. …”

A) Behavioral results of WM-load manipulation on subjects' hit rates (correct %) and reaction times (both <i>M</i>±<i>SEM</i>). by Christina Regenbogen (294120)

“…<p>In EEGfMRI subjects (n = 15) GLMs confirmed a significant increase in RTs and decrease in hit rates when WM-load increased. This was replicated in EEG-only subjects (n = 5), but only significant for hit rates. …”

Leading indicators of instability based on different elements of the covariance matrix (S_y), including the maximum (in absolute value) element, <i>Max</i>[S_y]... by Samir Suweis (596853)

“…<p>Random (l<i>eft</i>) and scale free (right) (30) network generated with <i>N</i> = 50 and <i>C</i> = 0.1 (main panels) and <i>N</i> = 0.1 and <i>C</i> = 0.5 (insets). Instability (i.e., decrease in <i>Max</i>[<i>Re</i>(λ)]) is attained by increasing the interaction strength <i>p</i> (mean field case). …”

The autophagy enhanced by downregulation of Chk-α contributed to protect MCF-7/TAM cells from tamoxifen. by Hoe Suk Kim (107279)

“…(B) Western blot analysis of the p62. 3-MA caused to a slight decrease in p62 level in MCF-7/TAM-shChk-α cells. Data are presented as the mean ± standard deviation of 5 independent experiments. …”

Immunofluorescence (IF) for Cx43 in hippocampus (A–D) and cerebellum (F–I). by Catarina Rapôso (5660521)

“…In the hippocampus, there was an intense decrease after 5 h of envenoming. E and J show the IF densitometric values for hippocampus and cerebellum, respectively (*p<0.05, **p<0.01 compared to control). …”

SB204741 restricts motion of pSRC. by James D. West (849663)

“…Values are expressed as mean ± standard error. n = 5–10, *p<0.05 compared to WT, #p<0.05 compared to vehicle treated.…”

Ryanodine-sensitive Ca²⁺ stores. by Ilanit Itzhaki (225708)

“…(<b>D</b>) Dose-response curve for the effects of ryanodine (5, 10, 15 and 20 µM) on whole-cell [Ca²⁺]_i transients amplitude displayed as the percentage of decrease from baseline values. …”

TGFβ induces migration in p53 null cells in comparison to p53 wild-type or mutant cells. by Eoghainín Ó hAinmhire (525379)

“…(<b>b</b>) Comparison of the fold increase of TGFβ samples from 5(a). Unpaired t-test was used to analyze significance. …”

Evaluation of salinity toxicity in biological nitrification effluent using the respirometry technique by Alyne Moraes Costa (6131834)

“…During the experiment, the bioreactor was operated with a hydraulic retention time of 48 h, and DO, pH and temperature maintained at 4.0-5.0 mg L-1, 7.5 and 25°-30°C, respectively. …”

CAR pre-treatment reduced infarct volume and improved neurological deficits after MCAO. by Hailong Yu (329340)

“…(D)Neurological scores were evaluated according to a 5-points scale system. CAR treatment significantly decreased neurological deficits. …”

Deletion of <i>IKBKAP</i> exon 20 results in grossly reduced DRG size and interruption of peripheral projections. by Shiran Naftelberg (3594614)

“…Scale bars 250 μm for panels A and F and 50 μm for panels B-E and G-J. (<b>K</b>) Quantification of average cell counts based on Drq5 immunostaining (n = 5 per group,*p<0.05), of total DRG size (in cm³, ***p<0.001), and of the Isl-1/Drq5 ratio for the CKO^<i>Tyrp2</i> FD DRGs compared to controls at E13.5 (***p<0.001). …”

Entrainment of network oscillations to weak electric field stimulation and effects on homeostatic synaptic downscaling. by Davide Reato (281995)

“…Note the rectification of the effect of fields on firing rate, which now only increases for inward stimulation but does not decrease for outward currents. <b>A.3</b>: Entrainment of the network with 0.31 V/m monophasic ON/OFF stimulation for purely cathodal (blue) or purely anodal (red) field. …”

Prostate cancer diagnosis, staging, and treatment in Sweden during the first phase of the COVID-19 pandemic by Giuseppe Fallara (9921948)

Repetitive stress induces a reduction in sound-evoked activity that develops as the stressor becomes chronic. by Ghattas Bisharat (20706928)

“…Comparison of tone-evoked activity after a day and 5 days of stress to baseline. On the initial day of stress, there was no significant reduction in activity, but as the stressor became chronic, the reduction increased (mean ± SE, 1-way ANOVA, condition S1 F = 1.9, <i>p</i> = 0.16, S5 F = 27.5, <i>p</i> = 1.7 × 10⁻⁰⁷, nested ANOVA (mouse nested within session) condition S1 F = 2.8, <i>p</i> = 0.09, S5 F = 32.7, <i>p</i> = 1.3 × 10⁻⁰⁸). …”

Manual RT-PCR measurements of 3 selected miRNAs agree very well with measurements performed by TLDA assay. by Neil R. Smalheiser (179141)

“…<p>The control and schizophrenia samples of Experiment 1 were measured using individual TaqMan primer sets for miR-17, miR-145-5p and miR-219-2-3p. Note that lower Ct values indicate higher abundance on a log2 scale (i.e., a decrease of 0.5 Ct represents a 41% increase in abundance or 1.41-fold difference across groups). …”

EEG and PSD Measures in Sleep-Deprived Monkeys by Linda J Porrino (380497)

“…Reduction of sleep deprivation features of PSD in same animals following administration of CX717 (0.8 mg/kg) is indicated at right by a decrease in PSD delta band (0.5–5 Hz, dotted line) and reduction in power of peaks (asterisks) in the beta band (18–25 Hz). …”

Early isolates of HIV-1 from the blood are deficient in binding and/or fusion with CD4 from some primate species. by Cody J. Warren (563898)

“…Data associated with this figure can be found in the supplemental data file (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000304#pbio.3000304.s009" target="_blank">S5 Data</a>). CCR5, C-C motif chemokine receptor 5.…”

Diet regulates the metabolic state and functioning of the heart during acute infection. by Fnu Nagajyothi (37087)

“…<p>(<b>a</b>) mPET analysis demonstrated a significant increase in the mean value of the myocardial standard uptake value for the glucose analogue, ¹⁸F-FDG in the infected RD fed mice compared to HFD infected mice at d30pi (n = 5). …”

DataSheet_1_Clinical manifestations and associated factors in acquired hypoaldosteronism in endocrinological practice.docx by Jorge Gabriel Ruiz-Sánchez (9704612)

“…</p>Results<p>Patients had a median age of 77 [65 – 84], 55.4% were male. 94.6% cases showed hyperkalemia, 54.5% HH, and 60.3% MA. The mean serum K+ of all cases was 5.4 ± 0.5 mmol/L, Na+: 132.1 ± 6.3 mmol/L, HCO3: 22.6 ± 3.3 mmol/L. …”

Defective <i>Foxo3</i>^<i>-/-</i> terminal erythroblast maturation. by Raymond Liang (352795)

“…Results are mean ± SEM of n = 4. (<b>B</b>) Gating of enucleating cells from the orthochromatic erythroblasts (in <b>A</b>) based on difference between the center of the nuclear stain and TER119 stain (Delta centroid on X) and a decreasing TER119 signal in the valley mask (highlighted in blue on TER119 image) which goes through the lowest signal point and thus marks the boundary between the reticulocyte and pyrenocyte. …”