Neurite degeneration following si<i>Nmnat2</i> injection precedes loss of neuronal viability. by Jonathan Gilley (126469)

“…<p>(A) Viability of wild-type SCG neurons injected with non-targeting siRNA (si<i>Control</i>) or <i>Nmnat2</i> siRNA (si<i>Nmnat2</i>), together with pEGFP-C1 (10 ng/µl), and treated with 50 µM z-VAD-fmk or vehicle (DMSO) as indicated. …”

Data_Sheet_1_Whole Body Vibration Improves Spatial Memory, Anxiety-Like Behavior, and Motor Performance in Aged Male and Female Rats.pdf by Tamás Oroszi (11983592)

“…WBV-treated rats showed a decrease in their anxiety level in the open field test compared with those in the pseudo-treated controls. …”

Durability of Triple Combination Therapy Versus Stepwise Addition Therapy in Patients With New-Onset T2DM: 3-Year Follow-up of EDICT by Muhammad Abdul-Ghani (4707436)

“…Thus, the difference in HbA1c between the two treatment groups at 3 years was 0.50% (95% CI=0.39-0.61, P<0.0001). …”

The Effect of Aerobic Exercise on Intrahepatocellular and Intramyocellular Lipids in Healthy Subjects by Andrea Egger (107540)

“…Two hours aerobic exercise resulted in a significant decrease in IMCL (−22.6±3.3, % from baseline) and increase in IHCL (+34.9±7.6, % from baseline). …”

Origin of Size Dependency in Coherent-Twin-Propagation-Mediated Tensile Deformation of Noble Metal Nanowires by Jong-Hyun Seo (1886029)

“…An elusive but fundamentally important question arises whether the size and surface effects impact the twin propagation behavior with a decreasing diameter. In this work, we demonstrate size-dependent strength behavior of ultrastrong and ductile metallic NWs. …”

Origin of Size Dependency in Coherent-Twin-Propagation-Mediated Tensile Deformation of Noble Metal Nanowires by Jong-Hyun Seo (1886029)

“…An elusive but fundamentally important question arises whether the size and surface effects impact the twin propagation behavior with a decreasing diameter. In this work, we demonstrate size-dependent strength behavior of ultrastrong and ductile metallic NWs. …”

Data_Sheet_1_Data-Driven Modeling of Global Storm Surges.PDF by M. Tadesse (8762661)

“…For extreme events, the average correlation decreases to 0.54 (0.33) and RMSE increases to 14.5 (13.1) cm for extratropical (tropical) regions. …”

Noise reduction and quantification of fiber orientations in greyscale images by Maximilian Witte (8313381)

“…A comparison to a state-of-the-art band-pass method revealed that the AF method is more suitable for the application on greyscale fiber images, since the error of the fiber dispersion significantly decreased from (33.9 ± 26.5)% to (13.2 ± 12.7)%. Both methods were found to accurately quantify the mean fiber orientation with an error of (1.9 ± 1.5)° and (2.3 ± 2.1)° in case of the AF and the band-pass method, respectively. …”

Impact on functionality of the paliperidone palmitate three-month formulation in patients with a recent diagnosis of schizophrenia: a real-world observational prospective study by Maria Paz Garcia-Portilla (8898926)

“…The total PSP score increased from a mean of 68.5 (15.3) at baseline to a mean of 72.1 (15.4) at month 6 and 74.8 (16.7) at month 12 with a before-and-after difference of 3.6 (95% CI, 1.6 to 5.5, p < 0.001) at month 6 and 6.2 (95% CI, 4.2 to 8.3, p < 0.001) at month 12. …”

data_sheet_1_Thymic B Cell-Mediated Attack of Thymic Stroma Precedes Type 1 Diabetes Development.docx by Ana Isabel Pinto (4221268)

“…By contrast, apoptosis of mTECs was decreased by 50% in B cell-deficient NOD mice suggesting intrathymic autoantibodies may selectively target certain mTECs for destruction. …”

Multiple-to-Multiple Relationships between MicroRNAs and Target Genes in Gastric Cancer by Yutaka Hashimoto (231668)

“…To find some groups of miRNAs that may synergistically regulate their targets in human gastric cancer (GC), we re-analyzed our previous miRNA expression array data and found that 50 miRNAs were up-regulated on treatment with 5-aza-2'-deoxycytidine in a GC cell line. …”

Effect of PPi on ΔΨm during anoxia+tachypacing in rabbit adult ventricular myocytes. by Junko Shibayama (387144)

“…The measurements were normalized to the baseline value recorded at immediately before the initiation of tachypacing (at the time point “−5 min”). ΔΨm-dependent TMRM signal was significantly different between control and PPi groups at all time points between 2 and 20 of tachypacing+anoxia (p<0.05).…”

Distinguishing orthosteric and allosteric effects in Hsp90. by Arun Chandramohan (2813848)

“…<p><b>(A)</b> The absolute difference in numbers of deuterons (y-axis) between the free and ligand bound state is plotted for each pepsin digest fragment listed from the N to C terminus (x-axis) of Hsp90 for each deuterium exchange time point (t = 0.5, 2, 5, 10 min) in a ‘difference plot’. …”

An overview of the Multi-CD method. by Ji Hyun Bak (2096773)

“…<p>(<b>A</b>) We first pre-process Hi-C data to extract a correlation matrix <b>C</b>. …”

<b>The association between glycemia, glycemic variability and pregnancy complications in early GDM</b> by Jincy Immanuel (17735170)

“…Women treated early (n=213) showed lower mean glucose (MG) and mean fasting glucose (MFG) compared with those treated late (n=116) (MG:5.7±0.4 vs. 5.9±0.5, p<0.001, MFG:5.2±0.3 vs. 5.3±0.4, p=0.004) with greater optimal glycemia (74.6% vs. 59.5%, p=0.006) and similar glycemic variability. …”

Image_2_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…GFP protein expression with the CAG promoter was highest at 3 weeks, and then decreased to stable levels at 3 and 6 months. Surprisingly, GFP mRNA levels continued to increase from 3 weeks to 3 months, despite GFP protein expression decreasing during this time. …”

Image_4_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…GFP protein expression with the CAG promoter was highest at 3 weeks, and then decreased to stable levels at 3 and 6 months. Surprisingly, GFP mRNA levels continued to increase from 3 weeks to 3 months, despite GFP protein expression decreasing during this time. …”

Table_1_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.pdf by Bradley S. Hollidge (14113539)

“…GFP protein expression with the CAG promoter was highest at 3 weeks, and then decreased to stable levels at 3 and 6 months. Surprisingly, GFP mRNA levels continued to increase from 3 weeks to 3 months, despite GFP protein expression decreasing during this time. …”

Image_3_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…GFP protein expression with the CAG promoter was highest at 3 weeks, and then decreased to stable levels at 3 and 6 months. Surprisingly, GFP mRNA levels continued to increase from 3 weeks to 3 months, despite GFP protein expression decreasing during this time. …”

Image_1_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…GFP protein expression with the CAG promoter was highest at 3 weeks, and then decreased to stable levels at 3 and 6 months. Surprisingly, GFP mRNA levels continued to increase from 3 weeks to 3 months, despite GFP protein expression decreasing during this time. …”