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point decrease » point increase (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
point decrease » point increase (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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15343
Data_Sheet_1_The Modulatory Role of CYP3A4 in Dictamnine-Induced Hepatotoxicity.docx
Published 2018“…Contrarily, the cytotoxicity was decreased in CYP3A4-inhibited PHH and CYP3A4 OE HepG2 and L02 cells inhibited by ketoconazole (KTZ). …”
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15344
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15345
The number of amyloid plaques and amount of Aβ<sub>1-42</sub> were reduced in S100A9 KO/Tg mice.
Published 2014“…Sections are 4 µm thick. ((a) – (h) Scale bar; 200 µm, (i)-(l) scale bar; 50 µm). …”
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15346
MDS erythroid precursors are deficient in membrane lipid rafts.
Published 2014“…Enlarged images illustrate lipid rafts at 630x with 6-zoom magnification. Bars represent 5 µm. (B) Statistically significant decrease in the number of rafts per cell in MDS erythroid precursors compared to normal donor erythroid cells, graph represents mean ± SE. …”
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15347
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15348
The conserved phenylalanine residue in PRMT5 is critical for inhibition by the five compounds.
Published 2017“…D, The F225M mutation in PRMT5 decreased the IC<sub>50</sub> values of the compounds, as determined by quantitation and analysis of methylation assay results.…”
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15349
Antimicrobial activity of RP-1 peptide conjugate with ferrocene group
Published 2020“…In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC<sub>50</sub> = 0.63 μmol L<sup>-1</sup>), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …”
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15350
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15352
Effect of DM, and/or <i>M. charantia</i> on the immuno-expressional level of NGF protein in maternal cerebellar tissue of different groups.
Published 2025“…The values are expressed as the means±SEM of 5 microscopic fields/tissue samples of NGF immune-expression, **<i>P</i> < 0.01.…”
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15353
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15354
Transition from scattered to smooth bell shaped distributions of <i>r<sub>v</sub></i> and <i>I</i> when grouping genes.
Published 2010“…<p>Distributions of (A) <i>r<sub>v</sub></i> and (B) <i>I</i> for ensembles of <i>n</i> randomly chosen genes from whole genomes (<i>n</i> = 10, 50, 100, 200, 500, 1000), estimated by Gaussian kernel with 100 repeats at a representative <i>t</i> = 48h (similar profiles are obtained for all time points), left panels for atRA and middle panels for DMSO response. …”
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15355
Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo
Published 2024“…Among them, compound <b>22o</b> exhibited remarkable antiproliferative activity against HeLa cells and was more potent than cisplatin (IC<sub>50</sub> = 2.80 vs 7.99 μM). Furthermore, mechanism studies indicated that <b>22o</b> inhibited cell metastasis, induced cell apoptosis, decreased mitochondrial membrane potential, and activated autophagy through the PI3K-Akt-mTOR signaling pathway. …”
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15356
Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo
Published 2024“…Among them, compound <b>22o</b> exhibited remarkable antiproliferative activity against HeLa cells and was more potent than cisplatin (IC<sub>50</sub> = 2.80 vs 7.99 μM). Furthermore, mechanism studies indicated that <b>22o</b> inhibited cell metastasis, induced cell apoptosis, decreased mitochondrial membrane potential, and activated autophagy through the PI3K-Akt-mTOR signaling pathway. …”
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15357
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15358
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15359
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15360