Showing 15,341 - 15,360 results of 49,971 for search '(( 50 ((we decrease) OR (a decrease)) ) OR ( 5 ((point decrease) OR (mean decrease)) ))', query time: 1.32s Refine Results
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    Data_Sheet_1_The Modulatory Role of CYP3A4 in Dictamnine-Induced Hepatotoxicity.docx by Zhuo-Qing Li (4455073)

    Published 2018
    “…Contrarily, the cytotoxicity was decreased in CYP3A4-inhibited PHH and CYP3A4 OE HepG2 and L02 cells inhibited by ketoconazole (KTZ). …”
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    The number of amyloid plaques and amount of Aβ<sub>1-42</sub> were reduced in S100A9 KO/Tg mice. by Hee Jin Kim (469168)

    Published 2014
    “…Sections are 4 µm thick. ((a) – (h) Scale bar; 200 µm, (i)-(l) scale bar; 50 µm). …”
  6. 15346

    MDS erythroid precursors are deficient in membrane lipid rafts. by Kathy L. McGraw (327439)

    Published 2014
    “…Enlarged images illustrate lipid rafts at 630x with 6-zoom magnification. Bars represent 5 µm. (B) Statistically significant decrease in the number of rafts per cell in MDS erythroid precursors compared to normal donor erythroid cells, graph represents mean ± SE. …”
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    The conserved phenylalanine residue in PRMT5 is critical for inhibition by the five compounds. by Gui-Mei Kong (4353751)

    Published 2017
    “…D, The F225M mutation in PRMT5 decreased the IC<sub>50</sub> values of the compounds, as determined by quantitation and analysis of methylation assay results.…”
  9. 15349

    Antimicrobial activity of RP-1 peptide conjugate with ferrocene group by Natalia C. S. Costa (8626206)

    Published 2020
    “…In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC<sub>50</sub> = 0.63 μmol L<sup>-1</sup>), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …”
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    Effect of DM, and/or <i>M. charantia</i> on the immuno-expressional level of NGF protein in maternal cerebellar tissue of different groups. by Amoura M. Abou-El-Naga (21001524)

    Published 2025
    “…The values are expressed as the means±SEM of 5 microscopic fields/tissue samples of NGF immune-expression, **<i>P</i> < 0.01.…”
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    Transition from scattered to smooth bell shaped distributions of <i>r<sub>v</sub></i> and <i>I</i> when grouping genes. by Masa Tsuchiya (78226)

    Published 2010
    “…<p>Distributions of (A) <i>r<sub>v</sub></i> and (B) <i>I</i> for ensembles of <i>n</i> randomly chosen genes from whole genomes (<i>n</i> = 10, 50, 100, 200, 500, 1000), estimated by Gaussian kernel with 100 repeats at a representative <i>t</i> = 48h (similar profiles are obtained for all time points), left panels for atRA and middle panels for DMSO response. …”
  15. 15355

    Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo by Er-Jun Hao (10097665)

    Published 2024
    “…Among them, compound <b>22o</b> exhibited remarkable antiproliferative activity against HeLa cells and was more potent than cisplatin (IC<sub>50</sub> = 2.80 vs 7.99 μM). Furthermore, mechanism studies indicated that <b>22o</b> inhibited cell metastasis, induced cell apoptosis, decreased mitochondrial membrane potential, and activated autophagy through the PI3K-Akt-mTOR signaling pathway. …”
  16. 15356

    Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo by Er-Jun Hao (10097665)

    Published 2024
    “…Among them, compound <b>22o</b> exhibited remarkable antiproliferative activity against HeLa cells and was more potent than cisplatin (IC<sub>50</sub> = 2.80 vs 7.99 μM). Furthermore, mechanism studies indicated that <b>22o</b> inhibited cell metastasis, induced cell apoptosis, decreased mitochondrial membrane potential, and activated autophagy through the PI3K-Akt-mTOR signaling pathway. …”
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