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33881
Table 7_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period-cohort analy...
Published 2025“…However, age-standardized deaths and DALYs significantly decreased across all five SDI regions. From an age effect perspective, globally, over 50% of COPD prevalence is concentrated among individuals aged 65 years and older, particularly in middle, low-middle, and high-middle SDI regions. …”
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33882
Supplementary file 2_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period...
Published 2025“…However, age-standardized deaths and DALYs significantly decreased across all five SDI regions. From an age effect perspective, globally, over 50% of COPD prevalence is concentrated among individuals aged 65 years and older, particularly in middle, low-middle, and high-middle SDI regions. …”
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33883
SPARC has therapeutic potential in severely virus-induced heart failure.
Published 2019“…<p>A—D In the more severe VM model mice are injected with 10<sup>4</sup> PFU CVB3, which results in severe cardiac inflammation after 1 week, and prominent fibrosis, but no cardiomyocyte hypertrophy after 5 weeks. E, F Viral infection caused severely decreased FS and dilation of the heart. …”
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33884
A role for <i>bmm</i> in the regulation of sex differences in triglyceride homeostasis.
Published 2020“…(E) Triglyceride levels were lower in 1-day-old <i>bmm</i><sup><i>rev</i></sup> males compared with newly eclosed <i>bmm</i><sup><i>rev</i></sup> males (<i>p</i> = 0.0013; Student <i>t</i> test); however, there was no significant difference in whole-body triglyceride levels between 1-day-old <i>bmm</i><sup><i>1</i></sup> males and newly eclosed <i>bmm</i><sup><i>1</i></sup> males (<i>p</i> = 0.0793; Student <i>t</i> test). (F) In 5-day-old <i>bmm</i><sup><i>rev</i></sup> males, whole-body triglyceride storage significantly decreased between 0 and 12 hours STV, with a further reduction between 12 and 24 hours STV (<i>p</i> = 6.2 × 10<sup>−5</sup> and 2.4 × 10<sup>−3</sup>, respectively; one-way ANOVA followed by Tukey HSD test). …”
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33885
TcdB3 has reduced binding to CSPG4.
Published 2021“…The percentage of rounded cells were plotted over toxin concentrations. Their CR50 were measured and plotted in a bar chart (I). …”
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33886
Optimization of sample collection, extraction and ELISA protocols to measure cortisol level in zebrafish larvae.
Published 2013“…(<b>E</b>) An incubation of HRP with TMB at a pH level of 4.5 gives the highest signal intensity, whereas signal detection decreases sharply at pH levels lower and higher than 3.5 and 6, respectively. …”
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33887
Table_2_“Longitudinal Fecal Microbiome Study of Total Body Irradiated Mice Treated With Radiation Mitigators Identifies Bacterial Associations With Survival”.xlsx
Published 2021“…Survival improved relative to control (30.0%) for G-CSF (80%, p-value = 0.025), G-CSF/JP4-039 (70%, p-value = 0.084), but not for JP4-039 (50.0%). In the second experiment, mice were administered mitigation drugs “inhibiting programmed cell death” pathways: JP4-039 (anti-apoptosis), necrostatin-1 (anti-necroptosis), and baicalein (anti-ferroptosis), in eight combinations. …”
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33888
FIGURE 3 from Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial–mesenchymal Transition in Aggressive Variant Prostate Cancers
Published 2023“…<b>B,</b> Apoptosis (caspase 3/7 assay): Levels of caspase 3/7 enzyme (a marker of apoptosis) activities measured followed CONV-TOPO, CONV-DTX, METRO-TOPO, and the combination of CONV-DTX + METRO-TOPO 72 hours treatment. …”
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33889
Table_3_“Longitudinal Fecal Microbiome Study of Total Body Irradiated Mice Treated With Radiation Mitigators Identifies Bacterial Associations With Survival”.xlsx
Published 2021“…Survival improved relative to control (30.0%) for G-CSF (80%, p-value = 0.025), G-CSF/JP4-039 (70%, p-value = 0.084), but not for JP4-039 (50.0%). In the second experiment, mice were administered mitigation drugs “inhibiting programmed cell death” pathways: JP4-039 (anti-apoptosis), necrostatin-1 (anti-necroptosis), and baicalein (anti-ferroptosis), in eight combinations. …”
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33890
DataSheet1_Selective Photocatalytic Oxidation of Glycerol and 3-Pyridinemethanol by Nanotube/Nanowire-Structured TiO2 Powders Obtained by Breakdown Anodization.docx
Published 2022“…<p>Nanotube/nanowire-structured TiO<sub>2</sub> was formed on the Ti surface by an anodic oxidation method performed at different potential values (50 or 60 V) and for different times (3 or 5 h). …”
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33891
Table_1_“Longitudinal Fecal Microbiome Study of Total Body Irradiated Mice Treated With Radiation Mitigators Identifies Bacterial Associations With Survival”.docx
Published 2021“…Survival improved relative to control (30.0%) for G-CSF (80%, p-value = 0.025), G-CSF/JP4-039 (70%, p-value = 0.084), but not for JP4-039 (50.0%). In the second experiment, mice were administered mitigation drugs “inhibiting programmed cell death” pathways: JP4-039 (anti-apoptosis), necrostatin-1 (anti-necroptosis), and baicalein (anti-ferroptosis), in eight combinations. …”
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33892
M disrupts the interaction between ATG14 and BECN1.
Published 2025“…<p>(A) Y2H assays showing the ATG14-N terminal interact with M. …”
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33893
Data_Sheet_2_Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma.pd...
Published 2018“…Density gradient ultracentrifugation was performed by loading plasma sample onto 50, 30, and 10% iodixanol layers and then centrifuged at 120,000 ×g for 24 h. …”
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33894
Data_Sheet_1_Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma.pd...
Published 2018“…Density gradient ultracentrifugation was performed by loading plasma sample onto 50, 30, and 10% iodixanol layers and then centrifuged at 120,000 ×g for 24 h. …”
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33895
Table_1_Effect of short-term mindfulness-based stress reduction on sleep quality in male patients with alcohol use disorder.DOCX
Published 2023“…</p>Objective<p>The aim of the present study was to evaluate the effect of short-term MBSR on sleep quality in male patients with AUD after withdrawal.</p>Methods<p>A total of 91 male patients with AUD after 2 weeks of routine withdrawal therapy were randomly divided into two groups using a coin toss: the treatment group (n = 50) and the control group (n = 41). …”
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33896
Increased Maf1 expression suppresses cellular transformation and tumorigenesis, consistent with its diminished expression in human cancer tissues.
Published 2014“…<p><u>Nuclear Maf1 expression is decreased in PTEN negative human prostate and liver cancers.…”
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33897
DataSheet1_Phytochemical characterization of Typha domingensis and the assessment of therapeutic potential using in vitro and in vivo biological activities and in silico studies.pd...
Published 2023“…TDME demonstrated significant (p < 0.05) potential in analgesic activity by hot plate and tail immersion tests and anti-inflammatory activity by the carrageenan-induced hind paw edema model. Pain latency decreased significantly, and the anti-inflammatory effect increased in a dose-dependent way. …”
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33898
Nogo-66 activated mTOR-STAT3 signaling in NPCs astroglial differentiation.
Published 2013“…<p>(A) Gel imagine of RT-PCR for NgR mRNA expression in NPCs. …”
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33899
Species- and life-stage-specific thermosensory behaviors and thermal physiology.
Published 2024“…<i>elegans</i> adults display a noxious heat escape response and have a very decreased lifespan, brood size, and hatching viability [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref034" target="_blank">34</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref037" target="_blank">37</a>–<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref039" target="_blank">39</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref042" target="_blank">42</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref043" target="_blank">43</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref050" target="_blank">50</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012529#pntd.0012529.ref069" target="_blank">69</a>].…”
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33900
Supplementary file 1_An expert patient program for people living with multiple sclerosis improves knowledge and empowerment: a pre-test, post-test multicenter implementation study....
Published 2025“…Hospital Anxiety and Depression Scale remained unchanged for anxiety and transiently increased for depression, whereas the Patient Activation Measure-13 increased at 12 months, by mean (SD) 2.04 [5.88] points (p = 0.0001) in patients with relapsing MS and by 3.28 (5.24) points (p = 0.0004) in those with progressive MS. …”