Dibucaine lessens dendritic beading induced by spontaneous spreading depolarizations (SDs) in penumbra. by W. Christopher Risher (213699)

“…<b><i>C</i></b>, Summary showing significantly decreased occurrence of dendritic beading (*<i>p</i><0.05; Chi-Square Test) when dibucaine is administered i.v. immediately following onset of the initial spreading depolarization. …”

Image_4_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.tif by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_10_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.tif by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_6_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_4_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_9_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.png by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_3_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.PNG by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_8_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_1_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_2_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_1_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.PNG by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_8_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.png by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Data_Sheet_1_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.docx by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_7_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.tif by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_3_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_11_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.tif by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_6_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.tif by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Table_7_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Image_2_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.PNG by Hongmei Li-Byarlay (5227208)

“…Using worker pupae, we studied the transcriptomic and methylomic consequences of IAPV infection over three distinct time points after inoculation. Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

N protein of SVCV inhibits p53 expression. by Shun Li (330132)

“…<p><b>(A)</b> SVCV infection decreases the expression of endogenous p53 protein. …”