A multi-centric Study of <i>Candida</i> bloodstream infection in Lima-Callao, Peru: Species distribution, antifungal resistance and clinical outcomes by Lourdes Rodriguez (3931793)

“…Overall, the 30-day survival was 60.4% (treated subjects, 67.4%; not-treated patients, 50.9%).</p><p>Conclusions</p><p>We found a very high proportion of non-<i>albicans Candida</i> species. …”

Locating dopamine receptors several microns away from the dopamine release site produces only a small change in cAMP signaling. by Rodrigo F. Oliveira (184716)

“…<p>A spatial gradient of dopamine decreases (A) cAMP and PKA activity as measured by (B) phosphoThr34 DARPP-32 and (C) phosphoSer845 GluA1, but no delay in time course. …”

Table1_Uncovering the clinical relevance of unclassified variants in DNA repair genes: a focus on BRCA negative Tunisian cancer families.xlsx by Maroua Boujemaa (5350577)

“…Family segregation analysis was also performed.</p><p>Results: Among a total of 37 VUSs identified, 11 variants are likely deleterious affecting ATM, BLM, CHEK2, ERCC3, FANCC, FANCG, MSH2, PMS2 and RAD50 genes. …”

Image1_Uncovering the clinical relevance of unclassified variants in DNA repair genes: a focus on BRCA negative Tunisian cancer families.pdf by Maroua Boujemaa (5350577)

“…Family segregation analysis was also performed.</p><p>Results: Among a total of 37 VUSs identified, 11 variants are likely deleterious affecting ATM, BLM, CHEK2, ERCC3, FANCC, FANCG, MSH2, PMS2 and RAD50 genes. …”

Data Sheet 2_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Results<p>Post-COVID-19, there was a significant increase in the scores for theoretical knowledge (77.10 ± 14.83 vs. 63.10 ± 15.11, p < 0.001) and understanding of infectious disease regulations (54.78 ± 15.94 vs. 50.85 ± 12.52, p = 0.001) among grassroots hospital physicians compared to pre-COVID-19 levels, albeit with room for further improvement. …”

Presentation_1_Neoadjuvant osimertinib and chemotherapy for stage IIIA primary pulmonary carcinosarcoma with EGFR 19DEL mutation: A case report.pptx by Hongming Wang (11756)

“…However, postoperative pathology revealed carcinosarcoma, pT2aN0M0, stage IB, and the pathological response was 50%. …”

Data Sheet 1_Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training.pdf by Irina A. Strigo (9745472)

“…Emerging evidence suggests that mind-body interventions, like our novel Mind Your Pain (MyP) smartphone mobile application, may offer relief. We conducted a single-arm, mixed-methods neuroimaging study to assess the degree to which treatment response to our 8-week intervention, as measured by the reduction in the Pain, Enjoyment of Life and General Activity Scale (PEG), was associated with enhanced pain-related insula activation over time.…”

Data Sheet 1_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Results<p>Post-COVID-19, there was a significant increase in the scores for theoretical knowledge (77.10 ± 14.83 vs. 63.10 ± 15.11, p < 0.001) and understanding of infectious disease regulations (54.78 ± 15.94 vs. 50.85 ± 12.52, p = 0.001) among grassroots hospital physicians compared to pre-COVID-19 levels, albeit with room for further improvement. …”

Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine by Barbara P. Sanders (2584447)

“…Furthermore, decreases in infectious titers, viral RNA, and protein levels were measured during infection at 37°C, suggesting a block in the viral replication cycle at RNA replication, protein translation, or earlier. …”

Image1_A simulation study on the climatic responses to short-lived climate pollutants changes from the pre-industrial era to the present.TIF by B. Xie (42914)

“…By looking at other variable responses, we found that precipitation had been increased by about 0.10 mm d⁻¹ in mid- and high-latitudes and decreased by about 0.20 mm d⁻¹ in subtropical regions, with the global annual mean value of 0.02 mm d⁻¹. …”

Assessment of Student Learning Outcomes for Assurance of Learning at Qatar University by Daoud, Khaled A

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Data Sheet 1_Clinical predictors and concomitant antiseizure medications effects on seizure control in relation to plasma cenobamate concentration: a multicenter retrospective stud... by Francesca Felicia Operto (12509263)

“…</p>Methods<p>We enrolled 53 adults with drug-resistant focal epilepsy, who started CNB with titration to 200 mg/day, were monitored monthly, and classified as responders (≥50% seizure reduction) or non-responders (<50%). …”

Functional effects of 10E8 on HIV-1 clade C variants including those with a naturally occurring L673 residue. by Arthur S. Kim (603570)

“…<p>(<b>A</b>) Partial neutralization by 10E8 of clade C isolates TM20.13 and M20490 BMR 211 using the TZM-bl assay. …”

Table_1_Erenumab for Migraine Prevention in a 1-Year Compassionate Use Program: Efficacy, Tolerability, and Differences Between Clinical Phenotypes.DOCX by Jean Schoenen (61359)

“…The lower efficacy in CM than in EM was mainly due to a very low 50% responder rate in patients with CM with continuous pain (13%) as compared to CM with pain-free periods (58%) (p < 0.001). …”

Specific and general adaptations following motor imagery practice focused on muscle strength in total knee arthroplasty rehabilitation: A randomized controlled trial by Armin H. Paravlic (7244804)

“…</p><p>Results</p><p>Significant differences in treatment effects were observed for the MIp group compared to CON: the MIp showed less strength decrease (ES = 1.15, 95% CI: 0.32, 1.99, p = 0.022); faster self-selected speed under single (ES = 2.12, 95% CI: 1.16, 3.08, p = 0.001) and dual task (ES = 1.59, large, 95% CI: 0.67, 2.50, p = 0.002) conditions; brisk-pace gait speed during single (ES = 1.32, 95% CI: 0.47, 2.17, p = 0.020) and dual task conditions (ES = 1.31, large, 95% CI: 0.38, 2.23, p = 0.013); improved chair sit-to-stand (ES = 1.45, large, 95% CI: 0.58, 2.31, p = 0.004) performance; and a higher score on MI ability questionnaires for kinaesthetic imagery (KI) (ES = 0.55, 95% CI: -0.23, 1.34, p = 0.010) and internal visual imagery (EVI) (ES = 0.99, 95% CI: 0.18, 1.80, p = 0.039) scales, respectively. …”

Image_1_Metyrapone Versus Osilodrostat in the Short-Term Therapy of Endogenous Cushing’s Syndrome: Results From a Single Center Cohort Study.jpg by Mario Detomas (11304897)

“…This tendency persisted at T2 (-37.3% vs -50.1%; median drug dose: 1250 mg vs 6 mg) while at T3 a decrease in UFC from T0 was more pronounced in the metyrapone group (-71.5% vs -51.5%; median dose 1250 mg vs 7 mg). …”

Table_1_Metyrapone Versus Osilodrostat in the Short-Term Therapy of Endogenous Cushing’s Syndrome: Results From a Single Center Cohort Study.docx by Mario Detomas (11304897)

“…This tendency persisted at T2 (-37.3% vs -50.1%; median drug dose: 1250 mg vs 6 mg) while at T3 a decrease in UFC from T0 was more pronounced in the metyrapone group (-71.5% vs -51.5%; median dose 1250 mg vs 7 mg). …”

Data_Sheet_1_Developing a nomogram-based scoring model to estimate the risk of pulmonary embolism in respiratory department patients suspected of pulmonary embolisms.CSV by Feng Lanfang (15184777)

“…The decision curve analysis (DCA) also demonstrated that the nomogram-based scoring model produced a favorable net clinical benefit.</p>Conclusion<p>In this study, we successfully developed a novel numerical model that can predict the risk of PE in respiratory department patients suspected of PE, which can not only appropriately select PE prevention strategies but also decrease unnecessary computed tomographic pulmonary angiography (CTPA) scans and their adverse effects.…”

Data_Sheet_1_A High-Throughput System for Cyclic Stretching of Precision-Cut Lung Slices During Acute Cigarette Smoke Extract Exposure.PDF by Jarred R. Mondoñedo (8939021)

“…CSE dose response curve was well characterized by a four-parameter logistic model (R² = 0.893), yielding an IC₅₀ value of 0.018 cig/mL. …”

Video_1_The interpositional bypass with a parietal branch of superficial temporal artery graft for symptomatic atherosclerotic anterior cerebral artery stenosis or occlusion.MP4 by Chuyang Tai (18312727)

“…The average follow-up period was 50.6 ± 18.3 months. The flow rate of the bypass was significantly increased half a year after surgery (56.2 ± 8.0 mL/min vs. 44.3 ± 5.3 mL/min, p < 0.001). …”