Extended exposure to extracellular adenosine (ADO) causes a dose-dependent reduction in chlamydial development via the A2b adenosine receptor. by Matthew A. Pettengill (256020)

“…(<b>B</b>) HeLa cell knock-downs (KDs) were produced with non-targeted (Control), A2a-targeted (A2a KD) or A2b-targeted (A2b KD) shRNA and levels of target KD verified to be decreased at least 50% by qPCR. …”

Fluorescence Imaging of the Oxidative Desorption of a BODIPY-Alkyl-Thiol Monolayer Coated Au Bead by Amanda Musgrove (1476934)

“…Fluorescence from the monomer and dimer were used to study the nature of the desorbed molecules during cyclic step changes in potential. The reductive desorption was observed to occur over a small potential window (0.15 V) signified by an increase in capacitance and in fluorescence. …”

Fluorescence Imaging of the Oxidative Desorption of a BODIPY-Alkyl-Thiol Monolayer Coated Au Bead by Amanda Musgrove (1476934)

“…Fluorescence from the monomer and dimer were used to study the nature of the desorbed molecules during cyclic step changes in potential. The reductive desorption was observed to occur over a small potential window (0.15 V) signified by an increase in capacitance and in fluorescence. …”

Fluorescence Imaging of the Oxidative Desorption of a BODIPY-Alkyl-Thiol Monolayer Coated Au Bead by Amanda Musgrove (1476934)

“…Fluorescence from the monomer and dimer were used to study the nature of the desorbed molecules during cyclic step changes in potential. The reductive desorption was observed to occur over a small potential window (0.15 V) signified by an increase in capacitance and in fluorescence. …”

Activated CD4+ CD45RO+ memory T-cells decrease secretion of soluble caspase-1 and P2X7R mRNA expression in monocytes leading to a reduced response upon ATP binding. by Vanessa Beynon (153924)

“…<p>a) sCaspase-1 levels in the supernatant of monocytes was measured by ELISA (n = 8). A significant decrease of soluble Caspase-1 in the supernatant of cells co-cultured with activated memory T-cells was observed both in the presence and absence of IFNβ; b) intracellular levels of pro-IL-1β measured with an ELISA specific for the immature precursor of IL-1β showed a significant increase in pro-IL-1β levels in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3), cell lysates from adherent monocytes were obtained after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP c) the ratio of intracellular pro-IL-1β to released soluble Caspase-1 is significantly increased in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3). d) <i>P2X7R</i> mRNA expression in monocytes cultured overnight with activated CD4+CD45RO+ memory T-cells is decreased with and without addition of exogenous IFNβ (n = 3), mRNA was isolated from adherent monocytes after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP (Data are shown as means ± SD of duplicate cultures; *p<0.05; **p<0.01 employing repeated measures ANOVA with post-hoc Bonferroni adjustment for multiple comparisons to avoid random correlations); e) Ca²⁺-influx measurement in monocytes cultured with activated human CD4+CD45RO+ memory T-cells in the presence of IFNβ demonstrates the absence of slow sustained Ca²⁺-influx mediated by ATP binding to the purinergic P2X7-receptor (representative of 3 independent experiments); f) Annexin V staining of monocytes coincubated with T-cells and stimulated with LPS was measured by flow cytometry (representative flow cytometry histogram of n = 5).…”

Hybrid stochastic framework predicts efficacy of prophylaxis against HIV: An example with different dolutegravir prophylaxis schemes by Sulav Duwal (152805)

“…Combining the population pharmacokinetics of DTG with the stochastic framework, we predicted that plasma concentrations of 145.18 and 722.23nM prevent 50- and 90% sexual transmissions respectively. …”

Decreased levels of CIITApIV H3K18ac, H3K27ac and CBP correlate with significantly elevated levels of H3K27me3 in metastatic breast cancer cells. by Agnieszka D. Truax (169208)

Concentration of suspended solids (mg /l) in six concentrations of water turbidity. by Javier Manjarrez (531011)

Weather conditions and variation in the numbers of female <i>Ae. aegypti</i> captured in SAGO traps. by Jesús A. Aguilar-Durán (9931967)

miRNA expression in pooled samples from univentricular heart failure patients. by Sweta Ramachandran (169036)

“…<p>Pooled sera from patients with Ross scores <3, 3–5, and >5 were evaluated for expression of miRNAs previously implicated as biomarkers of HF in adult patients. miR129-5p showed a decrease in expression with increasing Ross score. …”

Diameter at breast height (DBH) versus time for select trees from the different studies to highlight the variety of responses observed. by Brian J. Mailloux (190217)

MAD4 is a direct target of miR-125b-5p. by Valentina Manfè (189797)

“…(E) Evaluation of the efficient MAD4 silencing in SeAx cells by Western Blot. (F) Decrease of the percentage of the annexin-V positive cells after MAD4 silencing in SeAx cells treated with bortezomib (48h) comparing to scrambled siRNA. …”

Time-course of BCR-ABL and SFK dephosphorylation after treatment with inhibitors. by Adam Obr (541887)

Experimental tank to follow the predatory behaviors displayed by snake <i>T</i>. <i>melanogaster</i> over the fish <i>X</i>. <i>variata</i>. by Javier Manjarrez (531011)

Panel A–D shows the posterior mean distribution of PfPR_2–10 by the prediction years of 1969–1989 in Namibia. by Abdisalan M. Noor (82579)

“…The grey shade represents areas where transmission is unsuitable due to aridity. All maps are at 5×5 km spatial resolution.</p>…”

Mean lesion number and GBF in gastric mucosa of rats pretreated with NaHS or L-cysteine combined with COX-1 and COX-2 inhibitors. by Marcin Magierowski (702795)

“…Asterisk and cross indicate a significant (p<0.05) increase in mean lesion number and decrease in GBF as compared to respective values obtained in vehicle-control animals. …”

Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1 by Pamela Y. Ting (713174)

“…The CML cell line K562 was then used to identify five compounds that decrease MAPK1/3 phosphorylation, which we determined to be an indicator of RIN1-dependent ABL signaling. …”

Kidneys from Kif5b-Pax2KD (<i>Kif5bfl/-</i>:<i>Pax2-Cre</i>) embryos have a reduced cell proliferation rate. by Ju Cui (726069)

“…<i>Kif5b</i> deficiency significantly decreased BrdU incorporation in both ureteric bud and mesenchyme-derived epithelial structures, compared to wild type. …”

Plot showing average position (centroid) of predatory behavior of 18 treatments displayed by snake <i>T</i>. <i>melanogaster</i>, depending of three categories (few, median, many)... by Javier Manjarrez (531011)

Increased superoxide has a compartment specific effect on <i>clk-1</i> lifespan. by Claire E. Schaar (691681)

“…Deletion of either of the cytoplasmic <i>sod</i> genes (<i>sod-1</i>, <i>sod-5</i>) decreases <i>clk-1</i> lifespan. <b>C</b>. …”