Ductal branching is dependent upon phenotype heterogeneity within MCF10A in 3-D culture. by Russell Gould (3603524)

“…For compaction and tubular assays, cells were embedded into collagen gels for 72 hrs, and the extent of tubulogenesis was measured at 7 days. (A-D) Within MCF10A, TGF−<i>β</i>2 (10ng/ml) enhanced invasion and contractile properties while, VEGFA (50ng/ml) promoted increased migration. …”

Ubr3 is required for Hh signaling and proper optic vesicle morphogenesis. by Tongchao Li (115391)

Declining ELT-2 expression during aging limits lifespan. by Frederick G. Mann (263292)

Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication by Jun Li (6494)

“…The percentage of the sarcomere shortening (bl% peak h), departure velocity (dep v) of sarcomere shortening and time to 50% of the peak speed of myocyte contraction (Tp50) was assessed by a video-based edge-detection system. …”

Comparison of the bacterial 16S rRNA gene and fungal ITS rRNA gene copy numbers from the soils at the two sampling sites as determined by qPCR. by Niu Yayi (10834325)

Enhanced Rice Blast Resistance by CRISPR/Cas9-Targeted Mutagenesis of the ERF Transcription Factor Gene <i>OsERF922</i> by Fujun Wang (96184)

“…In recent years, sequence-specific nucleases (SSNs) have been demonstrated to be powerful tools for the improvement of crops via gene-specific genome editing, and CRISPR/Cas9 is thought to be the most effective SSN. Here, we report the improvement of rice blast resistance by engineering a CRISPR/Cas9 SSN (C-ERF922) targeting the <i>OsERF922</i> gene in rice. …”

Fig 1 - by Sławomir Grzegorczyn (12035398)

Neutrophil function assays completed on CGD patients off and after the 4^th dose of IFN-γ. by Daniel R. Ambruso (12042605)

“…Bars and brackets represent mean ± SEM with numbers of patients for each stimulus studied noted below. …”

Semi-log plot of the number of cities in IT provinces, <i>N</i>_{<i>c</i>,<i>p</i>}; the provinces are ranked by their decreasing “order of importance”, for various years;... by Marcel Ausloos (748325)

Semi-log plot of the number of cities in IT provinces, <i>N</i>_{<i>c</i>,<i>p</i>}; the provinces are ranked according to their decreasing “order of importance”, for vario... by Marcel Ausloos (748325)

Associations of baseline plasma BK and the sum of all unmodified bradykinin peptides with the ratio (5-year/baseline) of Sv(PGBM/glom) in the 243 RASS participants. by Kevin M. Wheelock (4237609)

“…Values above the dashed line reflect an increase in Sv(PGBM/glom) and those below the line a decrease over 5 years.</p>…”

Flow cytometry analysis of the changes in macrophage proportions in iNOS-KO and WT control rats. by Jia Shen (1828945)

Significantly changed USSs in the sf3b1 mutants. by Bei Zhang (428038)

Longitudinal assessment of animal weights and tumor metrics. by Robert Botelho (20308297)

Differentially expressed genes in <i>erg251Δ/Δ</i> in YPAD compared to wild-type in YPAD. by Xin Zhou (54275)

S2 Fig - by Pierre Ganault (17972799)

Flowchart of methods used to evaluate sensitivity to speed for the FEAR hypothesis, Looming stimulus hypothesis, and the Bayesian optimal escape model. by Ryan B. Lunn (12536881)

Effect of okadaic acid (OKA) on exflagellation and ookinete formation. by Yonghui Feng (12227596)

Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC₅₀ = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC₅₀ = 0.66 μM) and SW480 (IC₅₀ = 0.22 μM) cells. …”

Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

“…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC₅₀ = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC₅₀ = 0.66 μM) and SW480 (IC₅₀ = 0.22 μM) cells. …”