N⁶-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon blac... by Bin Han (45760)

“…After CB treatment, PI3K-AKT-mTOR pathway was activated and regulated by miRNA-126. We found that both of m⁶A modifications of pri-miRNA-126 and its binding with DGCR8 were decreased after CB treatment, which resulted in the reduction of mature miRNA-126 accompanied by accumulation of unprocessed pri-miRNA-126. …”

A Novel Splice-Site Mutation in Angiotensin I-Converting Enzyme (ACE) Gene, c.3691+1G>A (IVS25+1G>A), Causes a Dramatic Increase in Circulating ACE through Deletion of the Transmem... by Alexandre Persu (396983)

“…The levels of renin-angiotensin-aldosterone system components in the mutated cases and wild-type controls were similar, both at baseline and after 50 mg captopril. Compared with non-affected members, quantification of ACE surface expression and shedding using flow cytometry assay of dendritic cells derived from peripheral blood monocytes of affected members, demonstrated a 50% decrease and 3-fold increase, respectively. …”

DCP-LA treatment of SN56 cells diverts APP into early endosome compartments. by Joshua H. K. Tam (836784)

Mutational landscape of TCL cell lines. by Rufino Mondejar (4025846)

Baseline characteristics of the study sample^βμ. by Osama Mohamed Ibrahim (12006954)

“…Pharmacists in Active Group A (37.2%) and Active Group B (32.3%) most commonly intervened by recommending the cessation of medication, while the most common intervention in the Control Group was recommending a decrease in dose (29.8%). The mean cost reduction per patient was highest in Active Group A (31.3 ±11.8 $), followed by Active Group B (20.8 ±8.6 $) and the Control Group (19.6 ±9.5 $). …”

The flow diagram of the study (CONSORT, 2010). by Osama Mohamed Ibrahim (12006954)

“…Pharmacists in Active Group A (37.2%) and Active Group B (32.3%) most commonly intervened by recommending the cessation of medication, while the most common intervention in the Control Group was recommending a decrease in dose (29.8%). The mean cost reduction per patient was highest in Active Group A (31.3 ±11.8 $), followed by Active Group B (20.8 ±8.6 $) and the Control Group (19.6 ±9.5 $). …”

Table_1_Incidence and risk factors of severe acute high-altitude illness in healthy adults first entering the northern Tibetan Plateau of over 5,000 m.DOC by Chun Gao (622218)

“…</p>Conclusion<p>Living at lower altitudes and having a decreased lymphocyte level were the risk factors of severe AHAI in healthy adults first entering the plateau of over 5,000 m.…”

Systemic 5-FU treatment caused delayed increases in auditory brainstem response (ABR) inter-peak latencies P2-P1 and P3-P1 by Ruolan Han (35102)

“…At the later time points day 14 and day 56, both P2-P1 and P3-P1 inter-peak latency values of 5-FU-treated animals show average increases of more than 0.13 ms, whereas the same inter-peak latency values of sham-treated controls show average decreases or an increase of less than 0.04 ms. …”

1866 and DANA effects on MCD diet-induced changes in adipose tissue and liver weights. by Darrell Pilling (68014)

Hodgkin-Huxley-type multicompartment model of a layer 4 spiny stellate cell (L4SS). by Julia Jade Harris (7134944)

Rank-Order stability with longer conversations. by Grgur Kovač (19484728)

“…<p>Rank-order value stability (<i>Mean</i>±<i>SE</i>) following conversations of different length for the Mixtral-8x7B-Instruct-v0.1 model simulating fictional characters (correlation of simulated participants’ value expression in different contexts). …”

Spontaneous beating rates in mESC-CMs. by Yukihiro Saito (797587)

Effectiveness of community-based complementary food supplement (Yingyangbao) distribution in children aged 6-23 months in poor areas in China by Jie Wang (16762)

“…Compared with the baseline situation (n = 823), the proportion of children fed a diverse diet and foods rich in iron or vitamin A increased (<i>P</i> < 0.01) in the follow-up study. …”

DataSheet_1_A20 Establishes Negative Feedback With TRAF6/NF-κB and Attenuates Early Brain Injury After Experimental Subarachnoid Hemorrhage.zip by Hong-Ji Deng (11182902)

“…<p>Nuclear factor (NF)-κB–ty -50mediated neuroinflammation plays a crucial role in early brain injury (EBI) after subarachnoid hemorrhage (SAH). …”

Difficulty as a function of the level. by Federico Zimmerman (3607586)

Inhibition of vericiguat on CD16 and CD68 expression. by Weida Zhu (4352272)

Boxplots showing the effect of phenotypic variation between the two alleles of the SNP markers linked to QTLs for disease score of stripe rust. by Harpreet Singh (677440)

Supplementary Material for: Oral L-Arginine (5 g/day) for 14 Days Improves Microcirculatory Function in Healthy Young Women and Healthy and Type 2 Diabetes Mellitus Elderly Women by Costa G. (3075237)

“…All patients underwent biochemical analysis (fasting glycemia and lipidogram), arterial blood pressure, nailfold videocapillaroscopy (capillary diameters, functional capillary density [FCD], peak red blood cell velocity [RBCV_max] after 1 min ischemia, time to reach peak RBCV [TRBCV_max]), and venous occlusion plethysmography (vasoreactivity), before and after 14 days of oral supplementation with L-arginine (5 g/day). <b><i>Results:</i></b> L-Arginine did not change fasting glycemia and lipidogram, but it decreased systolic, diastolic, and mean arterial pressure in elderly women, increased RBCV_max in all groups, and did not decrease TRBCV_max in T2DME. …”

PDTC treatment alleviated oxidative stress in aortas of diabetic rats. by Chang-Wu Lu (4252060)

Two food choices profiles at Time 1 and Time 2. by Juan Cao (3145449)

“…</p><p>Method</p><p>Two-wave longitudinal data was collected from a sample of 431 Chinese college students (Mean baseline age = 19.15 ± 0.61 years; 45.7% male). …”