Search alternatives:
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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DataSheet_1_A phase I trial of SON-1010, a tumor-targeted, interleukin-12-linked, albumin-binding cytokine, shows favorable pharmacokinetics, pharmacodynamics, and safety in health...
Published 2024“…Despite some signs of efficacy since then, most rIL-12 clinical trials have encountered hurdles such as short terminal elimination half-life (T<sub>½</sub>), limited tumor microenvironment targeting, and substantial systemic toxicity. We developed a strategy to extend the rIL-12 T<sub>½</sub> that depends on binding albumin in vivo to target tumor tissue, using single-chain rIL-12 linked to a fully human albumin binding (F<sub>H</sub>AB) domain (SON-1010). …”
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Table 1_Proton therapy achieves high-dose tumor control with organ preservation in complex metastatic adenoid cystic carcinoma: a case report of a refractory patient with 16 pulmon...
Published 2025“…This approach represents a viable strategy for complex cases where conventional radiotherapy is contraindicated. …”
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17710
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17711
Bone Morphogenetic Protein for the Healing of Tibial Fracture: A Meta-Analysis of Randomized Controlled Trials
Published 2015“…The quality of the trial was assessed, and meta-analyses were performed with the Cochrane Collaboration’s REVMAN 5.0 software.</p><p>Results</p><p>Eight RCTs involving 1113 patients were included. …”
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17712
Prenatal medication use in a prospective pregnancy cohort by pre-pregnancy obesity status
Published 2021“…Since the study exclusion criteria limited the non-obese group to women without thyroid disease, in a sensitivity analysis we excluded all women who reported thyroid medication intake and still a higher proportion of women with obesity took the hormones and synthetic substitutes class compared to women without obesity.…”
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17713
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17714
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The effect of planting density on ‘BRS Rubimel’ peach trained as a “Y-shaped” system
Published 2019“…It was concluded that the densification of orchards is feasible for peach trees of the ‘BRS Rubimel’ cultivar due to the increase in productivity, without decreasing the quality of the fruits, indicating a spacing of 0.75 cm between plants and two scaffolds in the “Y-shape” as ideal. …”
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