Table 1_Global, regional, and national burden of intracerebral hemorrhage and attributable risk factors in youths and young adults, 1990–2021: a statistical analysis of incidence,... by Bing Wu (172312)

“…The incidence rate declined from 11.31 (95% UI, 8.56, 14.27) per 100,000 individuals in 1990 to 8.30 (95% UI, 6.46, 10.19) per 100,000 individuals in 2021, an overall decrease of −26.62% (95% UI, −30.85 to −22.24). Among the five Sociodemographic Index (SDI) regions, the highest EAPCs were observed in the high SDI regions for incidence (−1.63%; 95% CI, −1.74 to −1.52), mortality (−1.79%; 95% CI, −2.01 to −1.58), and DALYs (−1.67%; 95% UI, −1.84 to −1.50). …”

Interrelationship between mRNP components, PKA, and pseudohyphal growth MAPK signaling. by Christian A. Shively (531666)

Multiple endophenotypes exhibited by <i>bbs</i> mutants. by Calvin A. Mok (201207)

“…<p>(A) DiI uptake of <i>bbs</i> mutants was reduced compared to wild-type and transgenic <i>bbs</i> mutants carrying genomic DNA fragments for respective <i>bbs</i> genes. …”

Extracellular matrix-induced myelin sheet formation by oligodendrocytes requires Scribble. by Andrew A. Jarjour (343100)

“…D; Culturing oligodendrocytes on PDL-MG increased the proportion of cells exuding myelin-like membrane sheets (arrows in A). While Scribble knockdown in oligodendrocytes cultured on PDL did not affect the proportion of cells with membrane sheets, the percentage of cells with membrane sheets (arrows in B) was significantly decreased on PDL-MG. …”

Effects of temperature and photoperiod on diapause in hybrid swarm populations. by Priscilla A. Erickson (5003966)

“…<p>(A) Ovaries were scored based on the most advanced ovariole stage and the total number of eggs, according to King (1970) [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009110#pgen.1009110.ref066" target="_blank">66</a>]. …”

Integrated Role of Row Spacing and Adjuvant to Reduce Herbicide Dose in Maize Under Semi-Arid Conditions by M.A. NADEEM (4646020)

“…<div><p>ABSTRACT: Crop row spacing adjustment and adjuvants have a significant role in decreasing herbicide cost and environmental damage by reducing herbicide application rate. …”

Data_Sheet_1_Fungicide resistance in Botrytis cinerea and identification of Botrytis species associated with blueberry in Michigan.docx by Joel A. Abbey (10195437)

“…<p>Botrytis blossom blight and fruit rot, caused by Botrytis cinerea, is a significant threat to blueberries, potentially resulting in substantial economic losses if not effectively managed. …”

<i>skn-1</i> regulates AIY neuron morphology and food-seeking behavior by cell-autonomous and non-autonomous mechanisms. by Mark A. Wilson (208472)

“…AIY-specific expression of <i>skn-1b</i> has no effect on migration (B), and food-leaving behavior (C) (OP50 = 0.033x). Pan-neuronal expression of <i>skn-1b</i> significantly decreases AIY migratory defects (B) and partially rescues the food-leaving behavior (D). …”

Time course of wound closure in control and <i>holn1^c07150</i> mutant embryos. by Jennifer A. Geiger (194726)

“…<p>(A–B) Stills of wound closure process in <i>e22c>cherry-moesin</i> control (A) and <i>e22c>cherry-moesin</i>,<i>holn1^c07150</i> mutant embryos (B) at 1, 20, 50, 110, and 200 minutes after wounding. …”

Characterization of Rho-family GTPases’ effect on F-actin and cell shape. by Shamsideen A. Ojelade (795342)

“…Expression of constitutive active GTPases causes numerous changes in cell shape (**p < 0.01, t > 5.0, *p < 0.05, t = 2.45, DF = 124, n = 8–12). Note that Cdc42^CA causes a marked increase in elongated cells, similar to knock down of RhoGAP18B-PA. …”

Data Sheet 1_Assessing the efficacy and safety of pentoxifylline in preventing chemotherapy-induced peripheral neuropathy and mucositis in breast cancer patients.pdf by Samar A. Dewidar (22425457)

“…The outcomes of the present study include the occurrence of grade 2 or higher peripheral sensory neuropathy and mucositis evaluated according to common terminology criteria for adverse events (CTCAE v5.0).</p>Results<p>A total of 106 patients completed the study (PTX: 52; control: 54). …”

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

“…Here, we report the in vitro and in vivo characterization of the anti-inflammatory effects of CHF6297, a novel potent and selective p38α inhibitor designed for inhalation delivery as a dry powder formulation. …”

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

“…Here, we report the in vitro and in vivo characterization of the anti-inflammatory effects of CHF6297, a novel potent and selective p38α inhibitor designed for inhalation delivery as a dry powder formulation. …”

DataSheet1_A Novel System for Evaluating the Inhibition Effect of Drugs on Cytochrome P450 Enzymes in vitro Based on Human-Induced Hepatocytes (hiHeps).DOCX by Yan Li (23143)

“…The aim was to establish a novel evaluation system for the effect of drugs on CYP3A4, 1A2, 2B6, 2C9, and 2C19 in vitro based on hiHeps. …”

Low numbers of proliferating cells are observed in response to cerebral hypoperfusion however a proportion of newly generated cells differentiate into mature oligodendrocytes withi... by Jamie McQueen (518886)

“…<p>(A) Representative confocal images showing PCNA labelling of proliferating cells in the corpus callosum. …”

Data Sheet 1_Using a co-created checklist to improve on-farm biosecurity: an observational pilot intervention with pig farmers and livestock field officers in Sumbawanga, Tanzania.... by Aashima Auplish (17775827)

“…The median compliance score for biosecurity was significantly higher after the pilot intervention (20.0 out of 26 practices or 76.9%) compared to baseline (median of 5.50 out of 26 practices 21.2%). The time spent implementing biosecurity per sow (per day) increased from a median of 7.8–18.6 min by the end of the intervention. …”

Supplementary file 1_A diverse rotation of corn-soybean-winter wheat/double crop soybean with cereal rye after corn reduces tile nitrate loss.docx by Lowell E. Gentry (20703665)

“…Overall, tile nitrate loss was approximately 50% less in the diverse 3-year rotational system, suggesting that a more diverse rotational system is efficient at retaining N, conserving nitrogen in the field, and reducing N loss to surface water. …”

Table1_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Further, mitochondrial dynamics–related Mfn1 (0.47 of model, 0.82 of HTLN, 0.77 of LTLN, P＜0.01; 0.42 of 150 mM glucose, 0.56 of 10% TLN, 0.57 of 1% TLN, P＜0.01), Mfn2 (0.40 of model, 0.84 of HTLN, 0.63 of LTLN, P＜0.01; 0.46 of 150 mM glucose, 1.40 of 10% TLN, 1.40 of 1% TLN, P＜0.01), and Opa1 (0.58 of model, 0.71 of HTLN, 0.90 of LTLN, P＜0.01; 0.69 of 150 mM glucose, 0.96 of 10% TLN, 0.98 of 1% TLN, P＜0.05) were increased, while Drp1 (1.39 of model, 0.96 of HTLN, 1.18 of LTLN, P＜0.01; 1.70 of 150 mM glucose, 1.20 of 10% TLN, 1.10 of 1% TLN, P＜0.05), phosphorylated Drp1 (2.61 of model, 1.44 of HTLN, P＜0.05; 2.80 of 150 mM glucose, 1.50 of 10% TLN, 1.30 of 1% TLN, P＜0.01), and Drp1 located in mitochondria (1.80 of 150 mM glucose, 1.00 of 10% TLN, P＜0.05) were decreased after treatment with TLN. …”

Image1_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Further, mitochondrial dynamics–related Mfn1 (0.47 of model, 0.82 of HTLN, 0.77 of LTLN, P＜0.01; 0.42 of 150 mM glucose, 0.56 of 10% TLN, 0.57 of 1% TLN, P＜0.01), Mfn2 (0.40 of model, 0.84 of HTLN, 0.63 of LTLN, P＜0.01; 0.46 of 150 mM glucose, 1.40 of 10% TLN, 1.40 of 1% TLN, P＜0.01), and Opa1 (0.58 of model, 0.71 of HTLN, 0.90 of LTLN, P＜0.01; 0.69 of 150 mM glucose, 0.96 of 10% TLN, 0.98 of 1% TLN, P＜0.05) were increased, while Drp1 (1.39 of model, 0.96 of HTLN, 1.18 of LTLN, P＜0.01; 1.70 of 150 mM glucose, 1.20 of 10% TLN, 1.10 of 1% TLN, P＜0.05), phosphorylated Drp1 (2.61 of model, 1.44 of HTLN, P＜0.05; 2.80 of 150 mM glucose, 1.50 of 10% TLN, 1.30 of 1% TLN, P＜0.01), and Drp1 located in mitochondria (1.80 of 150 mM glucose, 1.00 of 10% TLN, P＜0.05) were decreased after treatment with TLN. …”

Image2_Tang Luo Ning, a Traditional Chinese Compound Prescription, Ameliorates Schwannopathy of Diabetic Peripheral Neuropathy Rats by Regulating Mitochondrial Dynamics In Vivo and... by Jiayue Zhu (10800972)

“…Further, mitochondrial dynamics–related Mfn1 (0.47 of model, 0.82 of HTLN, 0.77 of LTLN, P＜0.01; 0.42 of 150 mM glucose, 0.56 of 10% TLN, 0.57 of 1% TLN, P＜0.01), Mfn2 (0.40 of model, 0.84 of HTLN, 0.63 of LTLN, P＜0.01; 0.46 of 150 mM glucose, 1.40 of 10% TLN, 1.40 of 1% TLN, P＜0.01), and Opa1 (0.58 of model, 0.71 of HTLN, 0.90 of LTLN, P＜0.01; 0.69 of 150 mM glucose, 0.96 of 10% TLN, 0.98 of 1% TLN, P＜0.05) were increased, while Drp1 (1.39 of model, 0.96 of HTLN, 1.18 of LTLN, P＜0.01; 1.70 of 150 mM glucose, 1.20 of 10% TLN, 1.10 of 1% TLN, P＜0.05), phosphorylated Drp1 (2.61 of model, 1.44 of HTLN, P＜0.05; 2.80 of 150 mM glucose, 1.50 of 10% TLN, 1.30 of 1% TLN, P＜0.01), and Drp1 located in mitochondria (1.80 of 150 mM glucose, 1.00 of 10% TLN, P＜0.05) were decreased after treatment with TLN. …”