RNF5 depletion suppresses PEL xenograft tumor growth and decreases the levels of cell cycle gene expression and hedgehog signaling in tumors. by Xiaojuan Li (351842)

DAF-16/FOXO is Required for Locomotory Healthspan and Lifespan Benefits of Genetic Glycolysis Disruption. by Brian Onken (86790)

“…<i>daf-16</i> mutants are documented to have lowered locomotory ability vs. WT later in life [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref091" target="_blank">91</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref092" target="_blank">92</a>]; we note that, although comparison of scores across experiments is not possible due to variation in baseline values, the swimming rate of <i>daf-16(mgDf50)</i> control animals was slightly lower than WT controls on the same day of life (in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.g001" target="_blank">Fig 1C</a>; mean of 46.17 head thrashes/30 sec. for <i>daf-16</i> vs. 52.17 head thrashes/30 sec. for WT on day 10). …”

Cells with higher expression of a housekeeping gene have a decreased expression of viral genes. by Efrat M. Cohen (3384470)

A low dose of BCNU decreases division and promotes differentiation of O-2A/OPCs by Joerg Dietrich (35101)

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…The elimination of the slow population and the presence of a single diffusing population in [P₆₆₆₁₄][Cl] as the temperature increases and the viscosity decreases is consistent with liquid–liquid phase separation (LLPS) as a mechanism of nanodomain formation. …”

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…The elimination of the slow population and the presence of a single diffusing population in [P₆₆₆₁₄][Cl] as the temperature increases and the viscosity decreases is consistent with liquid–liquid phase separation (LLPS) as a mechanism of nanodomain formation. …”

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…The elimination of the slow population and the presence of a single diffusing population in [P₆₆₆₁₄][Cl] as the temperature increases and the viscosity decreases is consistent with liquid–liquid phase separation (LLPS) as a mechanism of nanodomain formation. …”

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

“…The elimination of the slow population and the presence of a single diffusing population in [P₆₆₆₁₄][Cl] as the temperature increases and the viscosity decreases is consistent with liquid–liquid phase separation (LLPS) as a mechanism of nanodomain formation. …”

Individual and mean EQ-5D VAS scores in the PP-group (0 = baseline, 1 = after the first day of treatment, 2 = after the second day of treatment, 3 = after the third day of treatmen... by Marcus Persson (20496333)

R848 mediated RANTES, but not TNF-α production, is significantly decreased in TRAM^−/− iBMDMs. by Enda Shevlin (628477)

Development of hiPSC-derived β-cells organoids and the effect of leucettines on the insulin production. by Barbara Pucelik (2988795)

The effects of pretreatment with fingolimod-phosphate on BMECs in the presence of MS sera. by Hideaki Nishihara (545149)

“…Pretreatment with fingolimod-phosphate resulted in an increase in the claudin-5 protein levels (B) and TEER values (G) and a decrease in the VCAM-1 protein levels (F) in the BMECs, which were upregulated after exposure to the sera from all MS patients, including the RRMS-R, RRMS-S and SPMS patients, compared to that observed in the cells not pretreated with fingolimod-phosphate.…”

Characteristics of samples used in this study (means ± SD). by Sergiy G. Gychka (13175728)

TPP decreases melanoma tumor growth rate when administered via hydrogel. by Kyle C. Kloepping (9928265)

Port-sourced PM_2.5 (μg/m³) concentrations 2017 at the Barcelona neighbourhood level. by Natalie Mueller (3406370)

Subjects:

Effects of 5-HTR blockade on incentive. by Yukiko Hori (299784)

Normalized pressure pain thresholds (PPTs) (mean ± SEM) at start, middle, end and 5 minutes after a standardized tourniquet test. by Jeanette Tour (10790855)

Mean of the electrocardiographic intervals during the treatment. by Thaysa de Sousa Reis (19338663)

Mean of the electrocardiographic intervals during the recovery. by Thaysa de Sousa Reis (19338663)

Predicted distance (km) needed to achieve a correlation coefficient of at least r =  0.50 using the median-based linear regression models. by Claire Stevens (11127729)