A dynamin-based inhibitory peptide (DYN) blocks LTP and the reduction of A-type K⁺ currents. by Sung-Cherl Jung (261358)

“…<p>In these experiments we included DYN in the patch pipette to prevent clathrin mediated endocytosis <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006549#pone.0006549-Kim2" target="_blank">[12]</a>. …”

CVA10-N142A is more resistant to anti-CVA10 sera and MAb 2A11 as compared to CVA10-WT. by Xue Li (285380)

Pharmacological inhibition of Nampt alleviates stress and skin inflammation in Spint1a-deficient larvae. by Francisco J. Martínez-Morcillo (11663364)

Adaptation of <i>B</i>. <i>subtilis</i> Rho⁺ cells to a sudden nutrient downshift. by Vladimir Bidnenko (4258573)

“…<i>subtilis</i> WT and Rho⁺ strains were cultivated in LB medium without or with RHX added at concentrations 50 and 100μg/ml in a 96-well microplate. Growth of the cultures was monitored by OD₆₀₀ measurement at the five-minute intervals using a microplate reader. …”

Effects of inserting AOP/LexA transgenes into <i>attP40</i> on nuclear clustering severity. by Kevin van der Graaf (14259532)

Titration results for BMV-1a helix A bound to SDS micelles with 16-DSA. by Ling Liu (143030)

“…a<p>50% signal intensity decrease with the addition of less than 3.2 mM DSA.…”

Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

“…An effective therapy for human adenovirus (HAdV) infections in immunocompromised patients and healthy individuals with community-acquired pneumonia remains an unmet medical need. We herein reported a series of novel substituted <i>N</i>-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide analogues as potent HAdV inhibitors. …”

CREB Targets Define the Gene Expression Signature of Malignancies Having Reduced Levels of the Tumor Suppressor Tristetraprolin by Mohammad Fallahi (200679)

“…These analyses defined a signature of 50 genes differentially regulated between high and low <i>TTP</i>-expressing tumors. …”

Pharmacological inhibition of pulmonary sensory neuron activity impacts IAV lung pathogenesis. by Nathalie A. J. Verzele (18389733)

Age-specific survival rate (<i>l</i>_<i>x</i>), fecundity (<i>m</i>_<i>x</i>), and maternity (<i>l</i>_<i>x</i><i>m</i>_<i>x</i>) of <i>A</i... by Aonan Zhang (8933630)

Age-specific survival rate (<i>l</i>_<i>x</i>), fecundity (<i>m</i>_<i>x</i>), and maternity (<i>l</i>_<i>x</i><i>m</i>_<i>x</i>) of <i>A</i... by Aonan Zhang (8933630)

The expression of <i>SATB2</i> (A) and <i>XLOC_036765</i> (B) at the four developmental phases in Landrace and Tongcheng pigs. by Yalan Yang (735975)

cGAS deficiency promoted EV-A71- and FMDV-induced mice death. by Huisheng Liu (408091)

Body weight and respiratory measurements following cellular ablation of lung pulmonary vagal afferents with AAVrg^{mCh FLEX DTA}. by Nathalie A. J. Verzele (18389733)

Satellite-Based Monitoring of Methane Emissions from China’s Rice Hub by Ruosi Liang (14018604)

“…Process-based modeling further suggests that this practice can lead to a reduction of methane emissions by more than 50% compared to continuous flooding of rice paddies and natural wetlands.…”

KIF4 knockdown blocks HBV entry and HDV infection into host cells. by Sameh A. Gad (12269979)

Image_1_Anti-tumorigenic and Platinum-Sensitizing Effects of Apolipoprotein A1 and Apolipoprotein A1 Mimetic Peptides in Ovarian Cancer.TIF by Aline T. Marinho (6267905)

“…The peptide at this concentration was not able to affect the viability of immortalized non-neoplastic ovarian cells (p > 0.05). ApoA1 decreased SKOV3 cells invasiveness at 300 μg/mL after 72 and 96 h of exposure (p < 0.05), while the ApoA1 mimetic peptide prevented cell invasion at 50 and 100 μg/mL (p < 0.01). …”

Pharmacological inhibition of pulmonary sensory neuron activity during IAV infection increases morbidity. by Nathalie A. J. Verzele (18389733)

Confirmation of AAV encoding Cre-inducible diphtheria toxin (AAVrg^{mCh FLEX DTA}) fucntionality. by Nathalie A. J. Verzele (18389733)

Image 9_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture in mi... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”