Signature of Aberrant DNA Methylation in <i>MYC</i>-Induced T cell Lymphomas by Rene Opavsky (32415)

“…Only data for RLGS fragments that have been methylated in more than 50% of tumors are shown. Methylation data from the analysis of three sets of EGFP-positive and EGFP-negative thymocytes isolated from 21-d-old <i>EμSR-tTA;Teto-MYC;Teto-Cre;Rosa26LOXP^EGFP</i> mice are also shown (see text and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030167#pgen-0030167-g002" target="_blank">Figure 2</a>).…”

DataSheet_1_Expression and Localization of Paneth Cells and Their α-Defensins in the Small Intestine of Adult Mouse.zip by Kiminori Nakamura (6400631)

“…Here we showed that levels of Crp mRNAs in the single crypt ranged from 5 x 10³ to 1 x 10⁶ copies per 5 ng RNA. …”

Predicting alternans in the Ca²⁺-driven model with positive Ca²⁺ to APD coupling during ramp pacing. by Mathieu Lemay (330649)

“…<i>Right</i>: using a SD of BCL of 5 ms, after adding a Gaussian error on APD (SD = 1 ms; windows of 150 cycles). …”

Data Sheet 2_Comparison with healthy controls: meta-analysis of changes in intestinal flora in Chinese patients with irritable bowel syndrome.zip by Hao Tu (16412994)

“…</p>Aim<p>To investigate differential characteristics of gut microbiota in Chinese patients with IBS compared to healthy controls (HC).</p>Methods<p>We conducted a comprehensive search in PubMed, Web of Science, Embase, and China National Knowledge Infrastructure (CNKI) databases from their inception to May 2025. …”

Data Sheet 1_Comparison with healthy controls: meta-analysis of changes in intestinal flora in Chinese patients with irritable bowel syndrome.zip by Hao Tu (16412994)

“…</p>Aim<p>To investigate differential characteristics of gut microbiota in Chinese patients with IBS compared to healthy controls (HC).</p>Methods<p>We conducted a comprehensive search in PubMed, Web of Science, Embase, and China National Knowledge Infrastructure (CNKI) databases from their inception to May 2025. …”

Visualization of Radial Peripapillary Capillaries Using Optical Coherence Tomography Angiography: The Effect of Image Averaging by Shelley Mo (3625997)

“…Quantitatively, number of endpoints decreased by 51%, and SNR, mean capillary length, capillary density, and ICD increased by 44%, 91%, 11%, and 4.5% from single frame to 10-frame averaged, respectively. …”

EEG delta power in NREM sleep after SD is associated with <i>Kif16b</i> and <i>Wrn</i>. by Shanaz Diessler (5617589)

“…For the δ1 increase after SD, we obtained a suggestive QTL on chromosome 8 and a significant prioritization score for the DNA-helicase <i>Wrn</i>. …”

SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs by Raed Shalaby (3756112)

“…<p>The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. …”

Supplementary Material for: Occurrence and Origin of Supernumerary Chromosomes in Partamona (Hymenoptera: Apidae: Meliponini) by Machado D.P. (3341064)

“…The frequency of the marker in <i>P. helleri</i> was correlated with the latitude of the sampling locality, decreasing from north to south. Sequence data on the SCAR marker from 50 individuals of the 6 species in which the presence of this marker was shown revealed a new scenario for the origin of the B chromosomes in <i>Partamona</i>.…”

Glycine negatively influences THN migration. by Ulrike Theisen (4734555)

“…(I) Magnification of region indicated in (F) to show that KCC2 may be present at the MHB and the ventral region of the rostral hindbrain at 30 hpf, although its expression is weak. Scale bar: 50 μm. See also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2002226#pbio.2002226.s005" target="_blank">S5 Fig</a>. …”

Datasheet1_Diagnostic and prognostic value of an ejection fraction adjusted for myocardial remodeling.docx by Wei Xuan Chan (11949866)

“…Both low EF and low EFa were associated with a high HF readmission risk. However, in the cohort with a normal EF (EF ≥ 50%), models using EFa were significantly more associative with HF readmissions within 3 years, where the leave one out cross validation ROC analysis showed a 18.6% reduction in errors, and Net Classification Index (NRI) analysis showed that risk increment classification of events increased by 12.2%, while risk decrement classification of non-events decreased by 16.6%.…”

Datasheet1_Diagnostic and prognostic value of an ejection fraction adjusted for myocardial remodeling.docx by Wei Xuan Chan (11949866)

“…Both low EF and low EFa were associated with a high HF readmission risk. However, in the cohort with a normal EF (EF ≥ 50%), models using EFa were significantly more associative with HF readmissions within 3 years, where the leave one out cross validation ROC analysis showed a 18.6% reduction in errors, and Net Classification Index (NRI) analysis showed that risk increment classification of events increased by 12.2%, while risk decrement classification of non-events decreased by 16.6%.…”

Validation of microarray results by qRT-PCR for 7 genes located within SPI-2. by Hyunjin Yoon (29786)

“…The results show that mutations in 6 regulators (<i>himD</i>, <i>phoP</i>/<i>phoQ</i>, <i>ssrA</i>/<i>ssrB</i>, <i>slyA</i>, <i>csrA</i>, and <i>ompR</i>/<i>envZ</i>) strongly decrease expression of SPI-2, in 5 strains there is a significant decrease (<i>hnr</i>, <i>rpoE</i>, <i>smpB</i>, <i>crp</i>, <i>hfq</i>) while in the remaining 3 no decrease or even an increase is observed for <i>fruR</i> (the others showing no change are <i>spvR</i> and <i>rpoS</i>).…”

Optimization of harvest preferences. by Alex Potapov (811655)

EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN1 by Salvador García-Carmona (20580797)

“…The aim of this study was to assess the changes that genetic material can exhibit and their impact on the production of proteins involved in the disease.</p> <p>We found a significant effect on genes that play roles in inflammation and detoxification processes in the body. …”

Inhibition of TPA-induced ERK activation partially restores chemotherapy-induced Mcl-1 degradation and cell death. by Shanna K. Nifoussi (128297)

“…The blot shown is representative of 3 independent experiments, where similar effects were seen with the various Ara-C concentrations as above (Fig. 5A). In the graph below the blot, the Decrease in Mcl-1 Expression (±SE) is plotted against PARP Cleavage (±SE), where points representing the average of cells treated with 1–10 mM Ara-C are labeled and the unlabeled points represent cells not treated with Ara-C. …”

Image_3_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Image_2_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Table_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Table_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”