IGF-1-induced enhancement of <i>PRNP</i> expression depends on the activation of PI3K-Akt signaling pathway. by Ting Liu (45625)

“…The LY294002-treated cells (lanes 2 and 6) showed a remarkable decrease in the PrP^C protein level compared with the DMSO-treated group (lanes 1 and 5). …”

Application of bar-code to cell counting studies. by Irina Krylova (585893)

“…<b>D,</b> LNCaP-C4-2 cells mixed, co-plated, treated exactly as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063286#pone-0063286-g005" target="_blank">figure 5B</a> then separated according to the bar-code showed similar treatment responses to the individually plated cells. …”

Reelin is secreted by GABAergic neurons. by Cecilia Gonzalez Campo (264260)

“…Treatment with BFA did not change the proportion of intense reelin IR neurons: 21.1±1.2% before treatment (n = 8) and 21.0±1.9% after 16 hours (n = 6), whereas it caused a significant decrease in the fraction of punctate reelin IR neurons. …”

Reduced Susceptibility of DNA Methyltransferase 1 Hypomorphic (Dnmt1^N/+) Mice to Hepatic Steatosis upon Feeding Liquid Alcohol Diet by Huban Kutay (144581)

“…<div><h3>Background</h3><p>Methylation at C-5 (5-mdC) of CpG base pairs, the most abundant epigenetic modification of DNA, is catalyzed by 3 essential DNA methyltransferases (Dnmt1, Dnmt3a and Dnmt3b). …”

Sialidase activity assay upon oseltamivir treatment <i>in vitro</i>. by Joana T. de Oliveira (718565)

“…<p>CMA07 and CMT-U27 cells were treated for 24 hours with different concentrations of oseltamivir phosphate (0.305 μM, 3.05 μM, 30.5 μM and 305 μM) or PBS as control, and incubated with a 2 μM 4-MuNana solution. …”

Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model by Aurigena Antunes de ARAÚJO (6403115)

“…Myeloperoxidase activity, malondialdehyde and glutathione levels, while interleukin-1 beta (IL-1β) and tumor necrosis factor-alpha (TNF-α) levels were evaluated by spectroscopic ultraviolet-visible analysis. A quantitative reverse transcription polymerase chain reaction was used to quantify the gene expression of the nuclear factor kappa B p50 subunit (NF-κB p50), phosphoinositide 3-kinase (PI3k), protein kinase B (AKT), and F4/80. …”

Structure of the Omicron epidemic waves models. by Bastien Reyné (20591988)

“…Before the emergence of the first Omicron VOC, we assume everyone has been immunised for SARS-CoV-2 (past infection or vaccination).…”

Loss of <i>Apc</i> causes spermatogonial stem cell (SSCs) depletion and blocks proliferation of SSCs in adult <i>Apc^Foxj1</i> testes. by Aimin Li (328168)

“…<p><b>A</b> Representative immunostaining of DDX4, DAZL and PLZF in control and <i>Apc^Foxj1</i> testis at 12 months are shown. …”

Cholesterol Diet Withdrawal Leads to an Initial Plaque Instability and Subsequent Regression of Accelerated Iliac Artery Atherosclerosis in Rabbits by Vivek Khanna (473366)

“…Atherosclerosis was thus induced in rabbits by a combination of balloon injury and atherogenic diet (AD) (1% cholesterol and 6% peanut oil) feeding for 8 weeks (baseline) followed by chow diet (CD) feeding for 4, 8, 16, 32, 50 and 64 weeks. …”

Data Sheet 1_Dietary supplementation with proanthocyanidins and rutin alleviates the symptoms of type 2 diabetes mice and regulates gut microbiota.docx by Yue Gao (263086)

Preferential Ionic Interactions and Microscopic Structural Changes Drive Nonideality in Binary Ionic Liquid Mixtures as Revealed from Molecular Simulations by Utkarsh Kapoor (3396041)

“…The self-diffusion coefficients of the ions were found to decrease monotonically with Cl^– concentration for both the mixtures. …”

In Situ Visualization of Concentration Polarization during Membrane Ultrafiltration Using Microscopic Laser-Induced Fluorescence by Bo-yang Meng (6334016)

“…The results showed that CP reached the steady state approximately 1 min after the filtration condition change. A higher cross-flow velocity and/or a lower TMP decrease the CP concentration and thickness. …”

Membrane potential measurements when SLO3 channel antagonists are present in capacitated wild-type and SLO3 mutant sperm; no significant changes in ion permeabilities are seen comp... by Julio C. Chávez (399841)

“…<p>Curves shown are GHK fits to wild-type (A) and SLO3 mutant sperm (B). When SLO3 channels are blocked in wild-type sperm, with either Ba²⁺ (1 mM), or clofilium (50 µM), no hyperpolarization is noted during capacitation and membrane permeability values are similar to those of non-capacitated wild-type sperm. …”

In Situ Visualization of Concentration Polarization during Membrane Ultrafiltration Using Microscopic Laser-Induced Fluorescence by Bo-yang Meng (6334016)

“…The results showed that CP reached the steady state approximately 1 min after the filtration condition change. A higher cross-flow velocity and/or a lower TMP decrease the CP concentration and thickness. …”

In Situ Visualization of Concentration Polarization during Membrane Ultrafiltration Using Microscopic Laser-Induced Fluorescence by Bo-yang Meng (6334016)

“…The results showed that CP reached the steady state approximately 1 min after the filtration condition change. A higher cross-flow velocity and/or a lower TMP decrease the CP concentration and thickness. …”

Ca²⁺ sparklets in DSM occur at different frequencies in the presence of CPA (10 μM). by Peter Sidaway (190696)

“…<p>Overlaid images (x60) of a preparation where (A) CPA (10 μM) caused an increase in sparklet frequency, and (D) where CPA (10 μM) caused a decrease in sparklet frequency, compared with the controls. …”

In Situ Visualization of Concentration Polarization during Membrane Ultrafiltration Using Microscopic Laser-Induced Fluorescence by Bo-yang Meng (6334016)

“…The results showed that CP reached the steady state approximately 1 min after the filtration condition change. A higher cross-flow velocity and/or a lower TMP decrease the CP concentration and thickness. …”

<i>In vitro</i> binding properties of <i>S</i>. <i>carpocapsae</i> FARs to fatty acids. by Sophia C. Parks (11624976)

“…C&D) When DAUDA is bound to FAR (13 μM) <i>in vitro</i>, a ~50nm blue shift is observed in the peak. E&F) Full curve of <i>in vitro</i> competition assays shows a decrease in fluorescence when linoleic acid (10 μM) binds to and therefore displaces DAUDA (1 μM) from the fatty-acid binding pocket of FAR. …”

The 4-aminopyridyl-based lead compounds. by Claudia Magalhaes Calvet (3601919)

“…Both compounds have EC₅₀ in low nanomolar range against cultured amastigotes, are orally bioavailable and decrease 99% parasitemia in mice after 4-day oral dosing [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0006132#pntd.0006132.ref035" target="_blank">35</a>,<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0006132#pntd.0006132.ref037" target="_blank">37</a>].…”

Visualization of association between score and threshold intensity and/or age. by Pavel Mareš (5689268)

“…<p>The multiplot visualizes the association of score (1–5) and (A) stimulation threshold or (B) age in males (blue) or females (red). …”