supplementary figures from Pharmacodynamic Response of the MET/HGF Receptor to Small-Molecule Tyrosine Kinase Inhibitors Examined with Validated, Fit-for-Clinic Immunoassays by Apurva K. Srivastava (14943418)

Concentration-response analysis of native <i>Eg</i>KU-1 on ASIC currents from DRG neurons. by Martín Fló (169408)

“…(B) Representative traces showing the acid (pH 6.1, 5 s) activated current under control conditions (left), after sustained (25 s) perfusion of α-DTX (center), and after 1 min washout (right). α-DTX (1 μM; n = 6) significantly decreased the current amplitude (44.5 ± 7.0%; P = 0.045). …”

Properties of the voltage-gated sodium current from honeybee ALNs. by Aklesso Kadala (659345)

“…<p>A, Sodium current traces obtained from an ALN for voltage steps to the indicated potential from a holding potential of −80 mV. …”

Fsn0503 inhibits angiogenesis <i>in vivo</i>; CD34 Immunohistochemical analysis of Fsn0503 treated tumors. by Claire Ward (362061)

“…<p>(<b>A</b>) Pattern of small vessel (white arrows) and large vessel (black arrows) distribution in isotype control and Fsn0503 treated tumors (10 mg/kg 5 times a week for 4 weeks) (20×). …”

DAG is required for vectorial progression of fusion. by Fabrice Dumas (243763)

“…Membrane fusion induces both a decrease of the lifetime and a spreading of BODIPY-C12 all around the nucleus. …”

Analytic solution for the traveling pulse in the real and complex eigenvalue case. by Laura R. González-Ramírez (692776)

“…<p><b>(a)</b> The onset of the pulse consists of a rapid increase in activity, followed by a rapid decrease due to adaptation, and then a monotonic return to rest (zero activity). …”

Summary of previously published data and present results. by María Luisa Hernández-Bule (506911)

“…<p>▴: statistically significant increase; ▾: statistically significant decrease; ND: no data; -: no significant (0.05Figs. 4A and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084636#pone-0084636-g005" target="_blank">5</a>); <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084636#pone.0084636-HernndezBule1" target="_blank">[15]</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084636#pone.0084636-HernndezBule2" target="_blank">[16]</a>: previously published data, see References.…”

Enzymatic activity analysis in human serum. by Andrew C. Nyborg (3597386)

“…<p>Substrate (UA) depletion assays were performed to assess uricase activity in 50% human serum. The rate (specific activity) of UA oxidation was calculated based on a linear decrease in absorbance. …”

Knockdown of <i>Lmo4</i> in the BLC leads to enhanced freezing to the context and the cue. by Rajani Maiya (123315)

“…B) Immunohistochemical analyses revealed a robust decrease in LMO4 expression in GFP positive/infected cells (arrows point to infected neurons, right panel) from shLmo4-injected mice but not from shScr-injected mice (arrows point to infected neurons, left panel). …”

The Cd content, chlorophyll content, and SOD and CAT activities changes under Cd stress in <i>M</i>. <i>lutarioriparia</i>. by Jia Wang (51945)

“…One enzyme unit (U) was equal to the amount used to inhibit 50% of the photochemical reduction of NBT, and a decrease in absorbance of 0.01 at OD240 nm minute−1 was considered to indicate 1 U of CAT activity. …”

Adult Hap1 expression reduces the stress-induced defective neurogenesis in the hippocampus and depressive-like behavior. by Jianxing Xiang (724184)

“…Immunostaining of BrdU in the DG was performed 1 day after the final treatment. Scale bar: 50 μm. The stressed groups showed fewer BrdU+ cells than non-stressed groups, and the decrease was more dramatic for stressed KO mice than stressed controls. …”

Silencing <i>HMGA1</i> expression halts cell growth and induces dramatic changes in cell morphology and gene expression. by Sandeep N. Shah (118905)

“…<p><b>A</b>) Lentiviral-mediated delivery of shRNA to <i>HMGA1</i> (denoted shHMGA1) results in a marked decrease in <i>HMGA1</i> mRNA and protein in triple negative breast cancer cell lines (MDA-MB-231, Hs578T). …”

Reduced UPEC-mediated inflammatory damage to bladder epithelium with AKB-4924 pretreatment. by Ann E. Lin (502380)

“…<p>(<b>A, B</b>) ELISA analysis shows pro-inflammatory cytokines IL-6, IL-1β or KC in the bladders or kidneys are reduced in AKB-4924 treated mice 18–24 h post UPEC CFT073 infection. …”

EVs obtained from U937 cells increased the expression of adhesion molecules in endothelial cells EA.hy926. by Myriam Lucia Velandia-Romero (8259726)

“…Cells infected with DENV-2 at MOI 0.2 (IC) showed a slight decrease in the expression of VE-Cad, while in cells exposed to <i>P (+ or -)</i> or <i>EV (+ 4G2 or UV)</i> showed a bright fluorescence pattern that delimits the cells. …”

Progressive differences between IPCs and OC surface proportions promoted 2° and 3° formation. by David E. Larson (246516)

“…‘No OC Expansion’, No Death' curve indicates constant OC surface area (no expansion) and no cell death. (<b>C</b>) A graph indicating the decrease in cell number for the different simulations. …”

Protean Agonism in the β₂-Adrenergic Receptor System by Tamara L Kinzer-Ursem (273905)

“…</p><p>(D) Desensitization treatment by isopreterenol is simulated by decreasing G protein (G_total) by 50%. Parameter values are equal to those listed in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030006#pcbi-0030006-g004" target="_blank">Figure 4</a> except when otherwise noted. …”

Potential benefits and neural correlates of adjunctive acupuncture therapyin unilateral stroke rehabilitation by Jia Fan (20107030)

Simulation-Based Approach to Data Fusion for Three Different Measures of Caspase Activity by John G Albeck (268792)

“…(C) An increase in T_s to 100 min (D) or a decrease in <i>f</i> to 0.1.</p> <p>(E, F, G) Concordance of data on EC substrate cleavage as obtained from immunoblot, flow cytometry, and live-cell assays in HeLa cells treated with 250 ng/ml (E), 50 ng/ml (F), or 10 ng/ml (G) TRAIL. …”

Expression of STUB1DN mutants leads to the formation of protein aggregates. by Joao Vasco Ferreira (7499918)

“…Cells were further incubated in the presence or absence of 10uM of MG-132 and 50nM of BafA for 6h. A) Cell extracts of proteins insoluble in increasing concentrations of SDS where filtered through a nitrocellulose membrane and trapped proteins were blotted with antibodies directed against ubiquitin, p62 and myc tag. …”

Regions of significant fractional anisotropy (FA) reduction in patients with panic disorder (PD) without comorbidity (N = 36) compared to healthy control (HC) subjects (N = 27).... by Borah Kim (556754)

“…<p>Voxels demonstrating significantly (threshold-free cluster enhancement, p<0.05 family-wise error corrected) decreased FA values for the PD group than for the HC group are shown in red-yellow (Z = −5 to Z = 25). …”