Image_3_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.jpeg by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

DataSheet_4_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.zip by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

DataSheet_1_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.pdf by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

Image_1_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.jpeg by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

DataSheet_3_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.zip by Yuan Gao (159945)

“…The treatment of BRAF^V600E and MEK inhibitor, PLX4720 and PD0325901, decreased the expression of miR-222-3p in B-CPAP but not in TPC-1. …”

Biochemical characterization of the endolysins of the lactococcal phages P008, c2, 1358, and P335. by Frank Oechslin (4825476)

“…The concentrations used corresponded to their specific activities, which were defined as the amount of enzyme needed to decrease the absorbance by 50% in 15 min (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001740#pbio.3001740.s016" target="_blank">S1 Data</a>). …”

Elimination testing with adapted scoring reduces guessing and anxiety in multiple-choice assessments, but does not increase grade average in comparison with negative marking by Jef Vanderoost (5108072)

“…The comparison is structured around seven hypotheses: in comparison with negative marking, elimination testing with adapted scoring leads to (1) a similar average score (no grade inflation); (2) students expressing their partial knowledge; (3) a decrease in the number of blank answers; (4) no gender bias in the number of blank answers; (5) a reduction in guessing; (6) a decrease in self-reported test anxiety; and finally (7) students preferring elimination testing with adapted scoring over negative marking.…”

Calcareous nannofossil biostratigraphy of the Late Cretaceous‒early Paleocene interval in the Zagros basin (southeastern Tethys), Iran by Azam Mahanipour (10126937)

“…This study concentrates on two sections (the Gurpi and Kabir-Kuh sections) in the west and southwest of Iran in the Zagros Basin, which span biozones CC25c/UC20bTP to NP6/NTp10B in the Kabir-Kuh and CC25b/UC20aTP to NP5/NTp9 in the Gurpi section. Late Maastrichtian nannofossil abundance and diversity in the studied intervals is high with a sharp decrease slightly above the K/Pg boundary. …”

Ras transformation affects the circadian clock via MAPK signalling. by Angela Relógio (193817)

“…(<b>B</b>) Western Blot analysis of RAS protein expression for the HaCaT cell lines and its derivatives (HaCaTI7, HaCaTII4, A5RT3), shows clear RAS overexpression measured in A5RT3. …”

Behavioral Logic for Operant Training and Discrimination Testing by Samar B Mehta (274037)

“…As this behavior was established, <i>N</i> was increased from 0.063 s to 1.5 s.</p> <p>(C) Stimulus training. All trials in this stage were initiated by a 1.5-s nose poke. …”

DataSheet_2_WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice.docx by Wenyan Li (255305)

“…Bioinformatic analyses showed that compared with wild type (WT), WAS knock out (KO)-CD4⁺ TEM cells exhibited increased Simpson index and decreased D50 index (P <0.05); The rank abundance curve of KO-CD4⁺ TEM cells was shorter and steeper than that of WT, and the angle of ^qD and q in KO-CD4⁺ TEM cells was lower than that of WT, while these indexes showed few changes between WT and KO chimeric mice in the CD8⁺TCM population. …”

DataSheet_1_WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice.zip by Wenyan Li (255305)

“…Bioinformatic analyses showed that compared with wild type (WT), WAS knock out (KO)-CD4⁺ TEM cells exhibited increased Simpson index and decreased D50 index (P <0.05); The rank abundance curve of KO-CD4⁺ TEM cells was shorter and steeper than that of WT, and the angle of ^qD and q in KO-CD4⁺ TEM cells was lower than that of WT, while these indexes showed few changes between WT and KO chimeric mice in the CD8⁺TCM population. …”

Pharmacometabolomics of Response to Sertraline and to Placebo in Major Depressive Disorder – Possible Role for Methoxyindole Pathway by Hongjie Zhu (152174)

“…Patients showing a good response to sertraline had higher pretreatment levels of 5-methoxytryptamine (5-MTPM), greater reduction in 5-MTPM levels after treatment, an increase in 5-Methoxytryptophol (5-MTPOL) and Melatonin (MEL) levels, and decreases in the (KYN)/MEL and 3-Hydroxykynurenine (3-OHKY)/MEL ratios post-treatment compared to pretreatment. …”

DTA-1-mediated depletion of tumor-infiltrating CD4⁺ Foxp3⁺ Treg cells by ADCC. by Mikiya Ishihara (611835)

“…<p>(A) DTA-1- (dotted line) or isotype control (solid line)-treated CMS5a and murine GITR gene-transfected CMS5a (CMS5a/GITR) cells were stained with a FITC-conjugated anti-rat IgG (H+L) antibody and analyzed by flow cytometry. …”

Representative confocal epifluorescent photomicrographs of <i>Schistosoma mansoni</i> sporocysts showing immunolocalization of anti-GST26 and anti-Prx1 antibodies after cultivation... by Marina de Moraes Mourão (189239)

“…By contrast, little difference in fluorescence levels was observed between the nonspecific GFP dsRNA control-treated (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000550#pntd-0000550-g002" target="_blank">Fig. 2C</a>) and Prx1/2 dsRNA-treated (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000550#pntd-0000550-g002" target="_blank">Fig. 2D</a>) sporocysts, reflecting the relatively small decrease (∼50%) observed in immunoblot protein levels. …”

Demonstration of MC migration toward glioma-conditioned medium. by Jelena Põlajeva (343919)

“…No statistical difference between <i>Ntv-a-</i> and <i>Gtv-a</i> lines was found. Scale bar = 50 µM. …”

Relation between chromosphere survival and motor improvement. by Alejandra Boronat-García (2950839)

“…The dotted horizontal lines denote a reduction in turn number of 50% and 100%. At the end of the experiment 6 out of 13 animals reduced their number of turns by ≥ 10%. …”

SB-216763 inhibits the GSK-3 pathway. by Pramod K. Dash (246530)

“…<p><b>A</b>) Representative images of western blots for phospho-GSK-3ß, phospho-LRP6, phospho-ß-Catenin, phospho-Akt, and phospho-ERK in response to i.p. injection of SB-216763 (2.5 and 5.0 mg/kg) or vehicle (0 mg/kg) (n = 3/group). …”

Supplementary Material for: Long-term trends in incidence, attack rates, and early case-fatality of spontaneous intracerebral hemorrhage. Dijon Stroke Registry (1985-2022) by figshare admin karger (2628495)

“…Results: 1,015 ICH cases (mean age 73.5 ±16.4 years old, 52.7% women) were recorded including 815 patients with a first-ever ICH and 200 cases of ICH as stroke recurrences. …”

PTEN regulates β-catenin activity in mammary stem/progenitor cells. by Hasan Korkaya (159560)

“…Perifosine treatment decreased the proportion of GFP-positive cells by more than 50%, whereas Bio treatment increased them more than 2-fold. …”