Maintenance regimen and adverse event management. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

BCC-specific survival. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

Abolishing the ordered neuron density gradient decreased the positive correlation observed for axon elongation scaling. by Sarah F. Beul (6008801)

Quantitative RT-qPCR demonstrate that Tat complex modulates expression of C5, CRLF2, APBA1, and BDNF. by Loreto Carvallo (4167607)

“…Tat complex increased the expression of C5 at 24 and 48 hours, decreased the expression of CRLF2 at 24 and 48 hours, increased the expression of APBA1 at 48 hours and increased the expression of BDNF after 24 hours of PMA treatment. …”

Basal ubiquitination of GlyT2 in neurons decreases when the pool of free monomeric ubiquitin is reduced. by Jaime de Juan-Sanz (386083)

HAART does not affect CTLA-4 expression, but significantly decreases CD39 expression in Tregs. by Pietro Presicce (144163)

HAART decreased enhanced expression of cell cycling markers in Tregs from HIV-infected subjects. by Pietro Presicce (144163)

ApoE3 decreases Rho activity and F-actin stress fibers in human VSMCs. by Bernadette Y. Hsu (753458)

ACE2 overexpression decreases collagen I levels in <i>mdx</i> TA muscle. by Cecilia Riquelme (546116)

Systemic inhibition of TGF-β decreases retinal smad2 phosphorylation <i>in vivo</i>. by Tony E. Walshe (269700)

“…(E) Western blot analysis of pp-smad2, smad2, pp-smad1/5/8 and GAPDH in mouse retinas from Ad-null and Ad-sEng-expressing mice (day 7). sEng-expressing mice displayed a decrease in retinal pp-smad2 (F). …”

Secreted Human Adipose Leptin Decreases Mitochondrial Respiration in HCT116 Colon Cancer Cells by Einav Yehuda-Shnaidman (461266)

“…Our results show that conditioned media from obese (vs. non-obese) subjects decreased basal (40%, <i>p<0.05</i>) and maximal (50%, <i>p<0.05</i>) OCR and gene expression of mitochondrial proteins and Bax without affecting cell viability or expression of glycolytic enzymes. …”

CaMKII inhibition does not alter dendritic spine density, but decreases dendritic length and complexity. by Jason R. Klug (132807)

WT1 (+KTS) decreases basal and GnRH-stimulated LHβ promoter activity. by Debalina Bagchi (686046)

The effect of MSC blocker GsMTx-4 on photoresponses from <i>Xenopus</i> rods. by Ulisse Bocchero (9128127)

<i>Pf-Rel</i> knockdown decreased the <i>Nacrein</i> gene expression level. by Juan Sun (439334)

“…<p>The expression levels of <i>Nacrein</i> (grey columns) and <i>Pf-Rel</i> mRNA (black columns) in oyster mantle were measured by Real-time PCR, 3 or 6 days after injection of <i>Pf-Rel</i> dsRNA. Five oysters (n = 5) were used in each experiment. …”

PLD1 inhibition decreases the c-Myc-dependent dNTP biosynthetic transcriptional program. by Harry E. Taylor (596259)

Excision of HIF1α decreases viral reactivation from latency in infected splenocytes in vivo. by Darlah M. López-Rodríguez (8098544)

The density of the Som+ cells in the EPL of the OB is significantly decreased in the Sp8 conditional mutant mice. by Xuhua Jiang (436379)

YTX treatment decreases tumour development in the B16F10 melanoma mouse model. by Araceli Tobío (3545306)

Loss of ALS2 results in decreased levels of the lysosome-dependent degradation of LC3 in fibroblasts. by Shinji Hadano (251529)

“…Fibroblasts derived from either wild-type (<i>Als2</i>^+/+) or <i>Als2</i>^−/− mice were incubated in a starvation medium with or without 0.5 µM chloroquine (CQ) for 6 hr. …”