The effects of pretreatment with fingolimod-phosphate on BMECs in the presence of MS sera. by Hideaki Nishihara (545149)

“…Pretreatment with fingolimod-phosphate resulted in an increase in the claudin-5 protein levels (B) and TEER values (G) and a decrease in the VCAM-1 protein levels (F) in the BMECs, which were upregulated after exposure to the sera from all MS patients, including the RRMS-R, RRMS-S and SPMS patients, compared to that observed in the cells not pretreated with fingolimod-phosphate.…”

AR-dependent tumor suppression was associated with increased cellular senescence. by Yelena Mirochnik (179447)

“…Male athymic mice (nu/nu, 5 mice/group) were injected s.c. with vector control (PC3-V) or PC3-AR cells and received Dox with drinking water, where indicated, to induce AR expression. …”

Increasing dead cell burden in wounds resulted in increased pro-inflammatory cytokine levels. by Savita Khanna (252283)

“…Data (mean ±SD, n = 5) are presented as <i>pg</i> cytokine per <i>mg</i> wound tissue. *, <i>p</i><0.05 compared to IgG treated control side.…”

Effects of CoQ₁₀ supplementation on oxidative stress induced by Rotenone and t-Butyl hydroperoxide (TBH). by Christian Bergamini (102106)

“…Asterisks refer to the statistically significant decrease of ROS production in Rotenone/TBH treated samples supplemented with quinones (n = 5, * p≤0.05); ** p≤0.001).…”

Between-group comparison: personal familiarity irrespective of stimulus type. by Luisa Jurjanz (351105)

“…<p>The figure shows brain areas with relative decrease in neural activity among aMCI patients when compared to control subjects, associated with familiar>unfamiliar stimulus content irrespective of stimulus type. …”

Different kinetics of cells positive to MPO in hamster and mouse ALAs model. by Andrea Cruz-Baquero (4347916)

“…In mice the MPO was positive at 6 and 12 h and decrease importantly at 24 h. Data represent the mean ± SD of three independent experiments (n = 5). …”

Effects of (a) AG-490 and (b) WHI-P154 on IFN-γ-induced nitric oxide (NO) generation in J774 macrophages by Outi Sareila (66176)

“…The values are mean ± SEM ( = 6), * < .05, and ** < .01 when compared to cells treated with IFN-γ alone.…”

Consumer Impacts (CI) for each reach (Within) and the differences (ΔCI) between reaches (Between). by Michael C. Marshall (130087)

“…Positive values indicate increase in response variable with consumers, whereas negative values indicate a decrease. Each bar is the mean (±1 SE) of 5 replicates. …”

Fluoro-Ruby-labeled motoneurons at 13 weeks after immediate nerve repair (A), 1 months delayed repair (B), 3 months delayed repair (C) and 6 months delayed repair (D). by Samuel Jonsson (284555)

“…(E) Histogram showing the quantification of mean±SEM number of regenerating spinal motoneurons after 0–6 months (mo) delayed repair. n = 5, *p<0.05 (3 mo vs, 6 mo), ***p<0.001 (0 mo and 1 mo vs 3 mo and 6 mo).…”

IL-1β treatment does not induce cell death. by Himakarnika Alluri (2735689)

“…<p>IL-1β (10 ng/mL; 2 hours) treatment had no effect on cell viability (n = 5). Hydrogen peroxide (used as a positive control) treatment decreases cell viability significantly (<i>p<</i>0.05). …”

Effect of α-synuclein siRNA on α-synuclein protein in the monkey substantia nigra. by Alison L. McCormack (362670)

“…Data are expressed as percent of the control value in the right (untreated) substantia nigra and represent mean ± SEM. A significant decrease is caused by α-synuclein but not luciferase siRNA in the left (siRNA-infused) hemisphere. …”

CD8 T cells from the mesenteric lymph node (MLN) also show reductions in proportion of antigen-experienced subsets with an increase in the naïve compartment. by Robert Harms (295592)

“…Bars represent mean. Data are from 2 experiments of 5 animals per treatment group per experiment.…”

Synergy of APAC and SLK on ex vivo platelet aggregate dissolution and platelet-rich clot lysis. by Suying Dang (340924)

“…The relative clot turbidity was calculated by detecting the decrease of the absorbance at OD405. The mean±SD. came from 3 separate experiments. …”

EPC-CM effects on tubular structure formation are AKT and ERK dependent. by Stefano Di Santo (359485)

“…Supplementation of EPC-CM with the inhibitor of AKT phosphorylation (CM+LY) ([5 µM]) substantially attenuated all three parameters while the addition of the inhibitor of ERK phosphorylation (CM+PD) ([10 µM]) resulted in a significant decrease of covered area and total tube length but had no significant effect on the reduction of the number of branches. …”

mRNA levels in Brockmann bodies of rainbow trout incubated <i>in vitro</i> for 1 h at 15°C in modified Hanks’ medium containing 2 mM D-glucose alone (control) or containing 1, 10,... by Marta Librán-Pérez (393255)

“…<p>Each value is the mean of 5 independent experiments carried out with pools of Brockmann bodies from 3–4 different fish. …”

Jackknife analysis of the top environmental predictors used in the model. by Kylie M. Sage (4543402)

“…BIO5 = maximum temperature of the warmest month, BIO6 = minimum temperature of the coldest month, BIO8 = mean temperature of the wettest quarter, BIO7 = annual temperature range, BIO15 = precipitation seasonality, BIO18 = precipitation of the warmest quarter, elv = elevation.…”

Machine learning methods identify putative commitment-associated genes from the committed progenitor (CP1) versus self-renewing (SR) populations. by Jose Teles (5655964)

“…Variable importance, as measured by the mean decrease in accuracy (left panel) or the Gini coefficient (right panel), was computed using the out-of-bag error. …”

FGF-9 Inhibits Infarct and Fibrosis in the Post-MI Diabetic Myocardium. by Dinender K. Singla (462521)

“…<b>H</b>: Histogram of mean left ventricular cardiac myocyte cross sectional interstitial fibrotic (IF) area (mm²). n = 5–8 animals/group. …”

gp120 activates IL-10 in a dose dependent manner unlike IL-6 and IL-6 induced STAT3 phosphorylation which get downregulated. by Roni Sarkar (390168)

“…Data represent the mean±SEM (n = 3). Statistical analysis was performed using Student's t-test, with the levels of significance defined as p*<0.05.…”

Superovulation alters global DNA methylation in early mouse embryo development by Bo Yu (241082)

“…Zygotes and 8-cell embryos were collected from each group and DNA methylomes were generated by whole-genome bisulfite sequencing. In the NM group, mean CpG methylation levels slightly decreased from zygote to 8-cell stage, whereas a large decrease in mean CpG methylation level was observed in both superovulated groups. …”