Gadolinium-free Magnetic Resonance Imaging of the Liver via an Oatp1-Targeted Manganese(III) Porphyrin by Nivin N. Nyström (13118188)

“…Controversy surrounding gadolinium-based contrast agents (GBCAs) has rendered their continued utility highly contentious, but the liver-specific GBCA Gd­(III) ethoxybenzyl-diethylene triamine pentaacetic acid (Gd­(III)-EOB-DTPA) remains in use because it provides unique diagnostic information that could not be obtained by any other means. To address the need for an alternate liver-specific MRI probe, we synthesized Mn­(III) 20-(4-ethoxyphenyl) porphyrin-5,10,15-tricarboxylate (Mn­(III)­TriCP-PhOEt), which exhibited significantly higher <i>r</i>₁ relaxivity than Gd­(III)-EOB-DTPA in vitro, while also targeting hepatocyte-specific organic anion-transporting polypeptide 1 (Oatp1) channels as a marker of viability. …”

Acetylated HIF-2α regulates <i>in vitro</i> tumor cell properties. by Rui Chen (95310)

“…Comparison of samples within a given condition on the day of interest was performed by two-way (cell proliferation) or one-way (colony formation, cell migration, cell invasion) ANOVA followed by Dunnett’s multiple comparisons test using control shRNA knockdown/control rescue as reference with decreased samples noted (*, P<0.05). For proliferation data, the indicated samples (*) differ from control cells for at least five of the last six days in this seven-day protocol. …”

Polyampholyte−Surfactant Film Tuning in Reverse Microemulsions by Mabya Fechner (1943278)

“…Additionally, the required amount of surfactant to establish a clear w/o microemulsion depends on the pH value, which means the hydrophobicity of the copolymers. Conductivity measurements show that droplet−droplet interactions in the w/o microemulsion are decreased at acidic but increased at alkaline pH in the presence of the copolymers. …”

Effect of combined thermal and water stress on germination of wheat seeds by Altamara Viviane de Souza Sartori (14211280)

“…The experimental design was completely randomized in a factorial scheme with four replications (four seed lots × 16 stress combinations), and means were compared using Scott-Knott 5%. We evaluated the germination of normal seedlings at 4 and 8 d, the activity of catalase and ascorbate peroxidase (APX), and the protein content of the aerial and root parts of wheat seedlings. …”

Assessment of B cell development in the BM of transgenic mice. by Ying Xing (278605)

“…(D) Numbers of preBII and immature B cells in B were calculated, and the ratios of immature cells to preBII cells were calculated as shown. Error bars represent means ± SD, *<i>P</i><0.05, **<i>P</i><0.01, n = 5. …”

Regulation of the SMN-interacting protein coilin. by Benjamin Förthmann (498522)

“…<p>Neuroblastoma SK-N-BE(2) cells were differentiated for different periods with retinoic acid (5 µM), lysed by sonification in modified RIPA-buffer <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082871#pone.0082871-Forthmann1" target="_blank">[7]</a> and analyzed by Western blot for coilin, SMN and α-Tubulin (A). …”

<i>Zfp804A</i> mRNA expression in the developing rat brain. by Katja Hvid Hinna (766041)

“…Expression is significantly increased in the adult rat compared to P5 (*<i>P</i><0.05). The zfp804A primer set was used and data are presented as means ± SEM. …”

Polyampholyte−Surfactant Film Tuning in Reverse Microemulsions by Mabya Fechner (1943278)

“…Additionally, the required amount of surfactant to establish a clear w/o microemulsion depends on the pH value, which means the hydrophobicity of the copolymers. Conductivity measurements show that droplet−droplet interactions in the w/o microemulsion are decreased at acidic but increased at alkaline pH in the presence of the copolymers. …”

Direct ionizing radiation and bystander effect in mouse mesenchymal stem cells by Amanda Nogueira-Pedro (12377818)

“…</p> <p><b>Methods and materials:</b> MSCs were irradiated (IR) and parameters related to DNA damage and cellular signaling were verified in a dose range from 0.5 to 15 Gy; also a transwell insert co-culture system was used to study medium-mediated BYS effects.…”

Markov chain diagrams and contrast index. by Guillermo E. Delmas (6169820)

“…<p>Markov chain diagrams are shown (the size of circle means of occupancy state rate and the arrow’s width are proportional to the probability of cooperate given (<b>A</b>) occupancy state and transition probabilities for an animal that disrupted its cooperative behavior when contrast index was changed to and pay-off matrix was changed [<i>P</i>_<i>T</i>, <i>P</i>_<i>R</i>, <i>P</i>_<i>P</i>, <i>P</i>_<i>S</i>] = [3<i>p</i>, 1<i>p</i>, 4<i>s</i>, 8<i>s</i>] to [5<i>p</i>, 1<i>p</i>, 4<i>s</i>, 8<i>s</i>] (p = pellet and s = seconds). …”

H89 and calyculin A inhibit the transcriptional activity of MR. by Hae-Ahm Lee (787353)

“…<p>HEK293 cells were stimulated with Aldo (10 nM) for 24 h after pretreatment with H89 (10 μM), calyculin A (5 nM), or vehicle for 6 h. Treatment with Aldo resulted in increased expression of <i>GILZ</i> (A) and <i>SGK-1</i> (B), which was decreased by pretreatment with H89 and calyculin A. …”

Image_1_Transcranial direct current stimulation alters sensorimotor modulation during cognitive representation of movement.TIFF by Gaia Bonassi (12750008)

“…<p>We recently demonstrated, by means of short latency afferent inhibition (SAI), that before an imagined movement, during the reaction time (RT), SAI decreases only in the movement-related muscle (sensorimotor modulation) and that a correlation exists between sensorimotor modulation and motor imagery (MI) ability. …”

Advanced control of codling moth (Cydia pomonella) using the beneficial nematode Steinernema carpocapsae in apple and pear orchards in the Pacific North West by Stephanie Haines (9726395)

“…Few biological control options are available, and the ones currently on the market, (e.g. viruses, plant extracts, and pheromones) tend to target 1^st instar larvae and adults. A promising means of decreasing codling moth populations is entomopathogenic nematodes (EPNs), specifically the species <i>Steinernema carpocapsae </i>(<i>Sc</i>)<i>, </i>which was originally isolated from codling moth larvae. …”

Effect of miR-21 inhibition in cell growth, proliferation and invasion. by Ileabett M. Echevarría-Vargas (568974)

“…Columns represent the means of triplicates ± S.E.M.</p>…”

Polyethersulfone hollow fiber membranes: effect of the internal liquid and the addition of clay by Rodholfo da Silva Barbosa Ferreira (6721565)

“…The membranes were characterized by contact angle (flat membrane), scanning electron microscopy (SEM) and flow measurements. By means of the contact angle measurements it was seen that the presence of clay favored an increase the hydrophilicity of the membranes. …”

Physiotherapeutic approach and functional performance after breast cancer surgery by Mariana Tirolli Rett (4648900)

“…DASH score decreased significantly from 28.06 ± 16.1 to 15.71 ± 10.7 (p = 0.001) meaning an improvement in functional performance of UL. …”

Automated disk-shaped pattern selection of parietal, post-orbital head region of eight geckos at nine weeks. by Maria Kiskowski (6619301)

“…Horizontal bars indicate 0.5 cm. Geckos are ordered by decreasing fractional spot area of the pattern (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006943#pcbi.1006943.t002" target="_blank">Table 2</a> for definitions). …”

Molecular Dynamics Simulations of Small Clusters and Liquid Hydrogen Sulfide at Different Thermodynamic Conditions by M. Albertí (1406524)

The miR-150 target MYB partially mediates miR-150 induced myeloid differentiation. by Valerie A. Morris (462679)

“…MYB protein was decreased in both miR-150 and miR-15a/miR-16 expressing HL60 cells after 96 hours of ATRA treatment, but was decreased to the greatest extent in miR-150 expressing cells. …”

Supplementary materials: Real-world clinical outcomes and rationale for initiating abatacept as a first-line biologic for patients with anticitrullinated protein antibody- and rheu... by Alexandrina Balanean (20282985)