Disruption of <i>UBP5</i> significantly down-regulates the capsule production. by Wei Fang (116739)

“…After statistical analysis, the capsule production of <i>ubp5</i>Δ strain (7.7±0.48%) significantly decreased compared with either WT (43.4±6.41%) or reconstituted strain (37.4±8.01%) (<i>P</i><0.001). …”

The time Britain’s rivers spent in five-degree temperature brackets (1982–2011). by Art R. T. Jonkers (3342131)

“…<p>(A): proportion of the year during which river segments reside in each five-degree temperature bracket: 0–5°C (open downward triangle); 5–10°C (open circle); 10–15°C (solid square); 15–20°C (solid upward triangle); the two warmer brackets increase in time span(solid line fits), whereas the two colder ones decrease (dashed line fits); (B,C): mean day of the year (1–365) on which segments cross the lower bound of the two highest brackets, resp. first entering (in panel B) and finally leaving (in panel C); both dates shift outward at similar mean rates; error bars: +/- standard error of the mean.…”

Locus deletion on chromosome 10 in the Lin5FU500.4 mutant. by Jean-François Ritt (488623)

“…Comparative genomic hybridization (CGH) experiments between Lin5FU500.4 and the WT strain. Grey, equal amount of DNA between the strains; black, decrease in the copy number of 5 genes clustered on chromosome 10 was observed in Lin5FU500.4. …”

MF induced EGFR interaction. by Xia Wu (203682)

“…C: The DEP FI decrease percentages in EGFR monomer solution with pretreatment of PD of a serial of concentration. …”

Improvement of physical and sensory properties of whipping cream by replacing sucrose with rebaudioside A, isomalt and maltodextrin by Mohamad Hossein AHOUEI (5996381)

“…Samples containing different amounts of rebaudioside A, isomalt and maltodextrin (50% Rebaudioside A+50%Isomalt, 50% Rebaudioside A +50%Maltodextrin, 50% Rebaudioside A +25%Isomalt+25% Maltodextrin, 60% Rebaudioside A +40%Isomalt, 60% Rebaudioside A +40% Maltodextrin, 60% Rebaudioside A +20%Isomalt+20% Maltodextrin) were stored for two months. …”

Improvement of physical and sensory properties of whipping cream by replacing sucrose with rebaudioside A, isomalt and maltodextrin by Mohamad Hossein AHOUEI (5996381)

“…Samples containing different amounts of rebaudioside A, isomalt and maltodextrin (50% Rebaudioside A+50%Isomalt, 50% Rebaudioside A +50%Maltodextrin, 50% Rebaudioside A +25%Isomalt+25% Maltodextrin, 60% Rebaudioside A +40%Isomalt, 60% Rebaudioside A +40% Maltodextrin, 60% Rebaudioside A +20%Isomalt+20% Maltodextrin) were stored for two months. …”

sGC expression remained constant, but cGMP and P-VASP/VASP ratio was decreased in aging resistance arteries; and FeTMPyP treatment reversed aging-related downregulation of the P-VA... by Lu Ma (46360)

“…<p>(A, B, D) sGC α1, sGC β1, cGMP, VASP and P-VASP immunostaining in resistance arteries. …”

Influence of COS on the activation of NF-κB in retina and RGC-5 cells. by I-Mo Fang (470460)

“…(B) COS decreased the amount of activated NF-κB translocated into nucleus in PQ-stimulated RGC-5 in a time-dependent and (C) dose-dependent manner. …”

SARS-CoV-2 Nsp14 interacts with human SIRT1. by Marius Walter (13775591)

“…Both drugs were cytotoxic at high concentrations and the apparent decrease in SIRT1 binding correlated with a similar decrease in the input lanes. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC₅₀ = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC₅₀ value. …”

CTCF is responsible for upregulation of PRMT5 under hypoxia in breast cancer cells. by Srinivas Abhishek Mutnuru (22513457)

“…<b>C)</b> Immunoblot showing decrease in PRMT5 expression upon CTCF KD under hypoxia in MCF7 cells. …”

Effect of <i>P</i>. <i>lilacinum</i> on fecundity and fertility of <i>Ceratits capitata</i>. by Wafa Djobbi (5180810)

Elasticity values for variables for a simulated population of female fishers. by Roger A. Powell (21222116)