SCU decreases ischemia area, improves endothelium-dependent vasodilation and influence of PKG inhibitor in MIR rats. by Lin Li (28817)

Intraperitoneal and intravenous administration of the TRPV3 agonist carvacrol decreases core temperature in conscious mice and rats. by Viktor V. Feketa (821190)

Structurally distinct inhibitors of Chk1 decrease Chk1 nuclear fluorescence following heating in a low well volume. by Andrew J. Massey (239469)

Pirfenidone stabilized the mitochondrial membrane potential (MMP) and decreased intracellular ROS in renal proximal tubular cells. by Jun-Feng Chen (494741)

Hybrid stochastic framework predicts efficacy of prophylaxis against HIV: An example with different dolutegravir prophylaxis schemes by Sulav Duwal (152805)

“…Once daily PrEP with 50mg oral DTG prevented 99–100% infections, and 85% of infections when 50% of dosing events were missed. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Twenty-one of the most prevalent human autoimmune diseases, in approximately decreasing order of prevalence [49], [275]. by Kenneth Andrew Ross (591738)

Inhibition of VEGF and CaMKII in OS cells dramatically decreases tumor growth <i>in vivo</i>. by Paul G. Daft (720351)

DMB treatment decreased neuronal apoptosis in cerebral ischemia. by Huinan Zhang (849524)

Fixation becomes unlikely with decreasing fitness of mutant homozygotes, variance in allele frequency increases with migration rate. by Philipp M. Altrock (340203)

Effects of functionalized multi-walled carbon nanotubes on toxicity and bioaccumulation of lead in <i>Daphnia magna</i> by Min-Hee Jang (827908)

“…The negatively charged C-MWCNT showed a notable decrease in lead toxicity (LC₅₀ value increased from 0.15 mg L^-1 to 1.08 mg L^-1 in the presence of 10 mg L^-1 C-MWCNT), whereas the positively charged N-MWCNT had only a slight effect on lead toxicity (LC₅₀ value increased from 0.15 mg L^-1 to 0.16 mg L^-1 in the presence of 10 mg L^-1 N-MWCNT). …”

Anti-CXCR3 group decreased number of specific CD8⁺ T cells as well as polyfunctionality after infection with <i>T</i>. <i>cruzi</i>. by Camila Pontes Ferreira (6194006)

Tg2576 mice treated with OG showed markedly increased α-secretase cleavage of APP and significantly decreased levels of Aβ generation. by She-Qing Zhang (446556)

Digraph showing relationships (arrows) for which we need accurate information in order to accurately predict species–specific shorebird responses to climate change. by Hector Galbraith (636637)

Image_3_Evidence for Decreased Density of Calretinin-Immunopositive Neurons in the Caudate Nucleus in Patients With Schizophrenia.TIF by Istvan Adorjan (8466846)

“…As expected, small, medium and large CR-ip interneurons were detected in the CN. We found a 38% decrease in the density of all CR-ip interneurons (P < 0.01) that was driven by the loss of the small CR-ip interneurons (P < 0.01) in patients with SCH. …”

Image_2_Evidence for Decreased Density of Calretinin-Immunopositive Neurons in the Caudate Nucleus in Patients With Schizophrenia.TIF by Istvan Adorjan (8466846)

“…As expected, small, medium and large CR-ip interneurons were detected in the CN. We found a 38% decrease in the density of all CR-ip interneurons (P < 0.01) that was driven by the loss of the small CR-ip interneurons (P < 0.01) in patients with SCH. …”