iFGFR1-induced CX3CL1 secretion by epithelial cells mediates macrophage migration. by Johanna R. Reed (306158)

“…Exposure to conditioned medium from CX3CL1 siRNA HC-11/R1 cells significantly decreased RAW 264.7 cell migration. Furthermore, addition of 50ng/mL rmCX3CL1 to CX3CL1siRNA HC-11/R1 cells at the time of B/B treatment rescued the loss of RAW 264.7 cell migration in cells exposed to conditioned medium from CX3CL1siRNA HC-11/R1 cells. …”

Reduced <i>Fgf8</i> expression in <i>Six1</i>^{<i>Cko/Cko</i>} mutant (<i>Eya1</i>^<i>CreER</i><i>;Six1</i>^<i>fl/fl</i> given tamoxifen from E11.5–12.5... by Ting Zhang (102583)

“…Two-tailed Student’s t-test was used for statistical analysis. Scale bars: 20 μm in A,B, 100 μm in upper panels of C,D and 50 μm in lower panels of C,D.…”

Data_Sheet_2_Moringa oleifera leaf polysaccharide alleviates experimental colitis by inhibiting inflammation and maintaining intestinal barrier.zip by Hosameldeen Mohamed Husien (13120816)

“…The aim of this study to investigate the potential effect of MOLP on UC in a mouse model as well as the underlying mechanism. …”

Supplementary file 1_EEG activity over ipsilateral and contralateral M1 during simple and complex hand tasks: variations with motor learning.docx by Jun Zhao (59250)

“…This supports the idea that iM1 plays a dynamic, task-dependent role in skill acquisition, consistent with prior proposals that iM1 activation scales with task demands.…”

Parkin protects zebrafish from heat shock-induced cell death. by Mareike E. Fett (362814)

“…<p>(<b>A</b>) Basal cell death is slightly increased in parkin-deficient zebrafish. …”

Selective human inhibitors of ATR and ATM render <i>Leishmania major</i> promastigotes sensitive to oxidative damage by Raíssa Bernardes da Silva (4694260)

“…<i>major</i> cells following H₂O₂ exposure whilst also decreasing their evaluated IC₅₀ to H₂O₂ to less than half of that observed for non-treated cells. …”

Table_2_The different effects of molybdate on Hg(II) bio-methylation in aerobic and anaerobic bacteria.XLSX by Lanjing Wang (16944130)

“…It is widely known that, as a metabolic analog, molybdate can inhibit the sulfate reduction process and affect the growth and methylation of sulfate-reducing bacteria (SRB). …”

CEACAM3 signaling is required for the PMN cytokine response to <i>N. gonorrhoeae</i>. by Anna Sintsova (437622)

“…<p>Inhibition of Src-family kinases and Syk leads to decreased cytokine production by infected PMNs. (<b>A, B</b>) WT and CEABAC PMNs were left untreated or pre-incubated with (<b>A</b>) Src-family kinase inhibitor (PP2, 10 µM), or (<b>B</b>) Syk inhibitor (piceatannol, 50 µM). …”

DataSheet_1_Optimizing the manure substitution rate based on phosphorus fertilizer to enhance soil phosphorus turnover and root uptake in pepper (Capsicum).docx by Kai Sun (140584)

“…</p>Methods<p>This research conducts a pot experiment with varying manure substitution rates (0%, 10%, 20%, 30%, 40%, 50%, 75% and 100%) based on P nutrient content to elucidate the mechanisms through which manure substitution affects P uptake in pepper.…”

Image_2_Fluorescent Microplastic Uptake by Immune Cells of Atlantic Salmon (Salmo salar L.).JPEG by Isabel S. Abihssira-García (9663956)

“…Salmon immune cells showed a relatively low ability to phagocytose microplastics. …”

Data Sheet 1_Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling.docx by Lanlan Sun (1798921)

“…Additionally, the combination of CSA and Clo reduced MDA levels by 13.4%, increased SOD activity by 9.7% and GST activity by 26.7%, while elevating GSSG content by 31.3% compared to Clo alone, ultimately mitigating oxidative damage in maize plants. qRT-PCR analysis showed that the expression of five P450 genes (CYP72A5, CYP81A4, CYP81Q32, CYP81A9, CYP81A36), nine GST genes (GST30, GST31, GSTIV, GSTVI, GST21, GST7, GST37, GST25, IN2-1), and two UGT genes (UGT76C2, UGT83A1) significantly high increased by 6.74-, 10.27-, 4.98-, 10.56-, 25.67-, 16.70-, 46.92-,7.53-, 5.10-, 238.82-, 143.50-, 4.58-, 31.51-, 39.3-, 4.20-, 10.47-fold after CSA+Clo treatment compared to that in the Clo treatment. …”

Figure 1; Figure 2; Figure 3; Figure 4; Figure 5; Table 1; Table 2; Table 3; Table 4; SupTable 1; SupTable 2; SupTable 3 by Ramachandran Chelliah (3837415)

“…</b> <b>Canonical NF-κB activation pathway and its transcriptional role in inflammation-associated bone loss:</b> In resting cells, the NF-κB complex (typically RelA/p50) is sequestered in the cytoplasm by IκBα. …”

Image_1_Fermentation weight loss, fermentation quality, and bacterial community of ensiling of sweet sorghum with lactic acid bacteria at different silo densities.pdf by Haiwen Xu (10453244)

“…Overall, sweet sorghum silage showed satisfactory fermentation quality, with a density of no <650 kg/m³, and inoculating LAB improved fermentation quality and reduced FWL. …”

Data_Sheet_1_Selenoproteins Protect Against Avian Liver Necrosis by Metabolizing Peroxides and Regulating Receptor Interacting Serine Threonine Kinase 1/Receptor Interacting Serine... by Tong Li (206968)

“…To reveal the underlying mechanisms of liver necrosis, a pool of the corn–soy basal diet (10 μg Se/kg; no VE added), a basal diet plus all-rac-α-tocopheryl acetate (50 mg/kg), Se (sodium selenite at 0.3 mg/kg), or both of these nutrients were provided to day-old broiler chicks (n = 40/group) for 6 weeks. …”

Image_2_TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve disease.TIF by Andrew J. McNair (9093310)

“…SMAD2 antagonism by siRNA and the SMAD7 agonist asiaticoside decreased detection of pSMAD by at least 50%, significantly decreased expression of the aVIC gene markers ACTA2, TAGLN, and MYH10, and pαSMA, pAKT2, and pERK1, but had no effect on pS6K, pERK2, or pVIM expression in aVICs. …”

Table_1_TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve disease.docx by Andrew J. McNair (9093310)

“…SMAD2 antagonism by siRNA and the SMAD7 agonist asiaticoside decreased detection of pSMAD by at least 50%, significantly decreased expression of the aVIC gene markers ACTA2, TAGLN, and MYH10, and pαSMA, pAKT2, and pERK1, but had no effect on pS6K, pERK2, or pVIM expression in aVICs. …”

Image_3_TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve disease.TIF by Andrew J. McNair (9093310)

“…SMAD2 antagonism by siRNA and the SMAD7 agonist asiaticoside decreased detection of pSMAD by at least 50%, significantly decreased expression of the aVIC gene markers ACTA2, TAGLN, and MYH10, and pαSMA, pAKT2, and pERK1, but had no effect on pS6K, pERK2, or pVIM expression in aVICs. …”

Data_Sheet_2_TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve disease.docx by Andrew J. McNair (9093310)

“…SMAD2 antagonism by siRNA and the SMAD7 agonist asiaticoside decreased detection of pSMAD by at least 50%, significantly decreased expression of the aVIC gene markers ACTA2, TAGLN, and MYH10, and pαSMA, pAKT2, and pERK1, but had no effect on pS6K, pERK2, or pVIM expression in aVICs. …”

Image_1_TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve disease.TIF by Andrew J. McNair (9093310)

“…SMAD2 antagonism by siRNA and the SMAD7 agonist asiaticoside decreased detection of pSMAD by at least 50%, significantly decreased expression of the aVIC gene markers ACTA2, TAGLN, and MYH10, and pαSMA, pAKT2, and pERK1, but had no effect on pS6K, pERK2, or pVIM expression in aVICs. …”

Data_Sheet_1_TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve disease.docx by Andrew J. McNair (9093310)

“…SMAD2 antagonism by siRNA and the SMAD7 agonist asiaticoside decreased detection of pSMAD by at least 50%, significantly decreased expression of the aVIC gene markers ACTA2, TAGLN, and MYH10, and pαSMA, pAKT2, and pERK1, but had no effect on pS6K, pERK2, or pVIM expression in aVICs. …”