BX-C genes control DT tube tapering. by Ryo Matsuda (685668)

“…This could be attributed to competition between the overexpressed proteins and endogenous <i>abdA</i> or <i>AbdB</i> [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004929#pgen.1004929.ref046" target="_blank">46</a>], leading to a systemic decrease of tube diameter.…”

The inhibitory effect of hUC-MSCs on intrahepatic cholangiocarcinoma. by Juan Liu (6492)

“…This growth inhibition was not due to a lack of required nutrients due to consumption during preparation of the conditioned media since cell proliferation did not change when treated with 50% hUC-MSC conditioned media together with increasing concentrations of fetal calf serum (10%, 25%, and 50%) (D). …”

Antitumor Activity and Induction of TP53-Dependent Apoptosis toward Ovarian Clear Cell Adenocarcinoma by the Dual PI3K/mTOR Inhibitor DS-7423 by Tomoko Kashiyama (162572)

“…In mouse xenograft models, DS-7423 suppressed the tumor growth of OCCA in a dose-dependent manner. Flow cytometry analysis revealed a decrease in S-phase cell populations in all the cell lines and an increase in sub-G1 cell populations following treatment with DS-7423 in six of the nine OCCA cell lines tested. …”

Data_Sheet_1_Biological Characterization of Hepatitis B virus Genotypes: Their Role in Viral Replication and Antigen Expression.docx by María Mercedes Elizalde (5184335)

“…Genotype A2 expressed the lowest pgRNA levels, with a 70-fold decrease in relation to the other genotypes (p<0.0001), while genotype B2 showed the lowest Precore RNA levels, with a 100-fold reduction compared to genotype A2 (p<0.0001). …”

Antigen B from <i>Echinococcus granulosus</i> enters mammalian cells by endocytic pathways by Edileuza Danieli da Silva (5176148)

“…AgB uptake was observed in four different cell lines, NIH-3T3, A549, J774 and RH. Inhibition of caveolae/raft-mediated endocytosis causes about 50 and 69% decrease in AgB internalization by RH and A549 cells, respectively. …”

General effects of training. by Marieke van der Linden (268336)

BBR increases autophagic activity in cultured cells. by Wenxiao Jiang (777255)

“…<p><b>(A)</b> Western blotting of LC3B in HEK293 cells transfected with or without Htt and treated with BBR (0, 5, 25, 50, or 100 μM). …”

The attenuating effects of Msi1 knockdown on Hh signaling in MSC proliferation and apoptosis. by In-Sun Hong (284033)

“…Purmorphamine increased cell proliferation (<b>A</b>) and decreased TUNEL-positive cell numbers (<b>B</b>), while the 50 nM Msi1 siRNA transfection produced the opposite effects. …”

Characterizing suboptimal child passenger safety practices in crashes with fatalities: Child, driver, vehicle, neighborhood, and policy factors by Arthi S. Kozhumam (14176683)

“…We sought to identify child, driver, vehicle, neighborhood, and policy-level factors associated with suboptimal child passenger safety practices in motor vehicle collisions (MVCs) with a fatality. …”

Graphene Oxide Grid Preparation by Thomas G. Martin (2619529)

“…</p> <p>Areas of criticism are a slight decrease in the electron transparency compared to graphene and a variance in support layer thickness due to the possible deposition of multiple layers of flakes in a random manner. …”

Effects of NMU on ITH mediated by two types of FcεRI cross-linking. by Yoshiko Mizukawa (3153414)

“…(B) ITH was induced by injecting 0.2 μg of TNP-specific IgE into the footpads of B6 or <i>Nmu</i>^-/- mice followed by the injection of 25 ng of anti-mouse IgE. NMU (50 pmol) or vehicle (PBS) was injected one day before injection of mice with an anti-mouse IgE (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0160122#pone.0160122.s001" target="_blank">S1B Fig</a>). …”

Responses to growth factors. by Kazunari Mouri (265029)

Video1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.AVI by Jose M. Ferrero (6705797)

“…In order to investigate these mechanisms, we developed a novel computational model of acute myocardial ischemia which couples a) an electrophysiologically detailed human cardiomyocyte model that incorporates modifications to account for ischemia-induced changes in transmembrane currents, with b) a model of cardiac tissue and extracellular K⁺ transport. …”

DataSheet1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.docx by Jose M. Ferrero (6705797)

“…In order to investigate these mechanisms, we developed a novel computational model of acute myocardial ischemia which couples a) an electrophysiologically detailed human cardiomyocyte model that incorporates modifications to account for ischemia-induced changes in transmembrane currents, with b) a model of cardiac tissue and extracellular K⁺ transport. …”

Loss of <i>bmm</i> function in the somatic cells of the gonad with an independent GAL4 line affects whole-body triglyceride breakdown in males but not females. by Lianna W. Wat (8339454)

“…(C) Between 0 and 12 hours STV, the magnitude of triglyceride breakdown in <i>tj>UAS-bmm-RNAi</i> was similar to <i>tj>+</i> and <i>+>UAS-bmm-RNAi</i> control males; however, between 12 and 24 hours STV, there was no significant decrease in triglyceride levels in <i>tj>UAS-bmm-RNAi</i> males, in contrast to <i>tj>+</i> and <i>+>UAS-bmm-RNAi</i> control males, in which we observed a significant decrease in triglyceride storage STV (<i>p</i> = 9.7 × 10⁻⁴, 0.0018, and 0.099 for 0–12 hours and 0.37, 1.9 × 10⁻⁵, and 0.028 for 12–24 hours, respectively; one-way ANOVA followed by Tukey HSD test). …”

Image_1_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Image_2_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Image_3_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Image_4_Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.tif by Csilla Fazakas (218764)

Image_1_Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.tif by Csilla Fazakas (218764)