Data_Sheet_1_Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.docx by Csilla Fazakas (218764)

Image_3_Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.tif by Csilla Fazakas (218764)

Image_2_Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.tif by Csilla Fazakas (218764)

Rearrangement of actin cytoskeleton in treated and untreated MDA-MB 435 breast cancer cells by Robert F. Klees (62686)

“…</p><p></p> Cells were plated on fibronectin for 4 hours in the presence of either compound 9 (panel (c)), compound A5 (panel (d)), or compound A8 (panel (e)) at a final concentration of 15.2 ng/μl and were compared to the positive control (panel (a)) and the ethanol vehicle (panel (b)).Cells were fixed and stained for F-actin using TRITC-phalloidin. …”

Fishery-Induced Changes in the Subtropical Pacific Pelagic Ecosystem Size Structure: Observations and Theory by Jeffrey J. Polovina (404674)

“…<div><p>We analyzed a 16-year (1996–2011) time series of catch and effort data for 23 species with mean weights ranging from 0.8 kg to 224 kg, recorded by observers in the Hawaii-based deep-set longline fishery. …”

53 proteins change in abundance with age. by Stephanie M. Zimmerman (449532)

<i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality... by Ashwani Kumar (55732)

“…The mechanistic interpretation of developed models explains the role of different structural attributes in predicting the pIC₅₀ of pyrazole sulfonamides extracted from the crystal structure of Leishmania major N-myristoyltransferase (NMT) along with co-crystallized myristoyl-CoA and ligands NMT106, NMT157, NMT187 and NMT236 (PDB ID: 4A2Z, 4A30, 4A32, 2WSA). …”

The Protein <i>O</i>-glucosyltransferase Rumi Modifies Eyes Shut to Promote Rhabdomere Separation in <i>Drosophila</i> by Amanda R. Haltom (664189)

“…The intracellular accumulation of Eys and the IRS defect worsen in <i>rumi</i> mutants raised at a higher temperature, and are accompanied by a ∼50% decrease in the total level of Eys. …”

Presentation_1_Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans.pdf by Emilia Boiadjieva Knöpfel (6795341)

“…We show that neutral amino acid antiporter LAT2 (Slc7a8) and uniporter TAT1 (Slc16a10) are expressed on mouse ciliary epithelium and LAT2 also in lens epithelium. …”

Epidemiology of sepsis in Brazil: Incidence, lethality, costs, and other indicators for Brazilian Unified Health System hospitalizations from 2006 to 2015 by Ricardo Alfredo Quintano Neira (5100806)

“…A total of 29.1% of the hospitalizations had admission to the intensive care unit (ICU) with a mean ICU LOS of 8.0 days. …”

Data Sheet 1_HLA class, calcineurin inhibitor levels, and the risk of graft failure in kidney recipients with de novo donor-specific antibodies.pdf by Marc-Antoine Béland (20294229)

“…Additionally, the risk of graft loss decreased with increasing CNI trough levels following dnDSA detection (aHR 0.7 [0.6-0.9] for each increase in 1 ng/mL, p=0.02).…”

Data Sheet 2_HLA class, calcineurin inhibitor levels, and the risk of graft failure in kidney recipients with de novo donor-specific antibodies.pdf by Marc-Antoine Béland (20294229)

“…Additionally, the risk of graft loss decreased with increasing CNI trough levels following dnDSA detection (aHR 0.7 [0.6-0.9] for each increase in 1 ng/mL, p=0.02).…”

Data Sheet 1_Milciclib-mediated CDK2 inhibition to boost radiotherapy sensitivity in colorectal cancer.pdf by Junjie Ma (730463)

“…When combined with irradiation, Milciclib led to a 20% increase in the proportion of cells in the G1 phase and a 10% decrease in the G2 phase, suggesting an alteration in cell cycle distribution. …”

Table_1_The Impact of COVID-19 Confinement on Tinnitus and Hearing Loss in Older Adults: Data From the LOST in Lombardia Study.DOCX by Carlotta Micaela Jarach (12203687)

“…In 2020 compared to 2019, among individuals with tinnitus, those with increasing severity (5.0%) were similar to those decreasing it (5.3%). …”

Neural activity in the brains of workers exposed to high temperature or IAA. by Atsushi Ugajin (178472)

“…In the brains of heat-exposed bees, the dotted <i>Acks</i> signals were detected most densely in the Class II KCs (D and G) and moderately in the restricted area between the DLs and OLs (J), and much less densely in the Class I KCs (A), whereas there was some decrease in the <i>Acks</i> signals in the Class II KCs of antennae-deprived and heat-exposed workers (E and H). …”

Study group background characteristics. by Zicheng Hu (3825313)

“…The blood CD4+ T-cell concentrations in the 5 groups defined by these counts show the stepwise decrease from >500 to <50 CD4+ T-cells/μL dictated by the study design. …”

Crz signaling influences osmotic and ionic stresses. by Meet Zandawala (491178)

Static adhesion of tumor cells to protein-immobilized poly-dimethylsiloxane wells. by Sara P. Y. Che (718192)

“…The positive control had no antibody pretreatment, and isotype IgG pretreatment (50μg/ml) was used as a negative control. Blocking FVIIa binding to TF with the TF9-5B7 antibody significantly decreased adhesion to TFPI-coated wells compared to controls (* p < 0.05, n = 3). …”

Supplementary Information Files for Early childhood weight gain: latent patterns and body composition outcomes by Tom Norris (5153441)

“…Supplementary Information Files for Early childhood weight gain: latent patterns and body composition outcomes<br>Background: Despite early childhood weight gain being a key indicator of obesity risk, we do not have a good understanding of the different patterns that exist. …”

Phase difference, spatial synchrony, and phase coherence plots. by Yi Hu (58993)

“…The error bars are standard deviation from mean phase difference. <b>b/f</b>, Phase difference from Huangzhong and Fengxian (as a function of population size for neighboring counties, within 70 km of Huangzhong and 50 km of Fengxian). …”